ChemicalBook > CAS DataBase List > 5-Bromo-2-fluoropyridine

5-Bromo-2-fluoropyridine

Product Name
5-Bromo-2-fluoropyridine
CAS No.
766-11-0
Chemical Name
5-Bromo-2-fluoropyridine
Synonyms
5-BROMO-2-FLUOROPYRIDINE;5-Brom-2-fluorpyridin;3-BROMO-6-FLUOROPYRIDINE;5-BROMO-2-FLUO;2-Fluoro-5-bromopyri;2-FLUORO-5-BORMOPYRIDINE;3-fluoro-5-bromopyridine;2-Floro-5-Bromo Pyridine;2-FLUORO-5-BROMO PYRIDINE;5-Bromo-2-fluoropyridine>
CBNumber
CB0344067
Molecular Formula
C5H3BrFN
Formula Weight
175.99
MOL File
766-11-0.mol
More
Less

5-Bromo-2-fluoropyridine Property

Boiling point:
162-164 °C750 mm Hg(lit.)
Density 
1.71 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.5325(lit.)
Flash point:
165 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-2.79±0.10(Predicted)
form 
Liquid
color 
Clear colorless yellow
Specific Gravity
1.710
BRN 
1363171
InChI
InChI=1S/C5H3BrFN/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey
MYUQKYGWKHTRPG-UHFFFAOYSA-N
SMILES
C1(F)=NC=C(Br)C=C1
CAS DataBase Reference
766-11-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37-37/39
RIDADR 
UN2810
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
520438
Product name
5-Bromo-2-fluoropyridine
Purity
99%
Packaging
5g
Price
$22.54
Updated
2025/07/31
TCI Chemical
Product number
B2705
Product name
5-Bromo-2-fluoropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$96
Updated
2025/07/31
TCI Chemical
Product number
B2705
Product name
5-Bromo-2-fluoropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$248
Updated
2025/07/31
TRC
Product number
F588785
Product name
2-Fluoro-5-bromopyridine
Packaging
10g
Price
$150
Updated
2021/12/16
Apolloscientific
Product number
PC10362
Product name
5-Bromo-2-fluoropyridine
Purity
99%
Packaging
5g
Price
$10
Updated
2021/12/16
More
Less

5-Bromo-2-fluoropyridine Chemical Properties,Usage,Production

Description

5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.

Chemical Properties

5-Bromo-2-fluoropyridine is a colourless or yellowish liquid compound with a density of 1.71 g/cm3 at 25° C; boiling point of 162-164° C (lit.) at 750 mmHg; stored at room temperature.

Uses

5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.

Synthesis

403-45-2

766-11-0

A. Synthesis of 2-fluoro-5-bromopyridine: 2.2 g (15.6 mmol) of 6-fluoronicotinic acid, 5.1 g of red mercuric oxide (HgO) and 1.2 ml of bromine were dissolved in 100 ml of carbon tetrachloride (CCl4) to form a suspension. The reaction was carried out under reflux conditions for 5 hours and subsequently cooled to room temperature. The reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated under vacuum. The residue was dissolved in hexane, filtered again and the filtrate was concentrated under vacuum to give 1.73 g (63% yield) of 2-fluoro-5-bromopyridine, the product being a light yellow oil.

References

[1] Patent: US5618821, 1997, A

5-Bromo-2-fluoropyridine Preparation Products And Raw materials

Raw materials

Hexane N,N-Dimethylformamide Potassium hydroxide Hydrogen peroxide Ethyl acetate 2-Amino-5-bromopyridine Tetrabutylammonium fluoride Sulfuric acid

Preparation Products

5-BROMO-2-FLUOROPYRIDINE-3-CARBALDEHYDE
More
Less

5-Bromo-2-fluoropyridine Suppliers

Americas 1 Belgium 1 Canada 2 China 416 Europe 3 France 2 Germany 8 India 42 Italy 1 Japan 2 Jordan 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 17 United States 52 Global 552
Beijing DeLee Pharma Technology Co.,Ltd.
Tel
17316103847
Email
sales@deleepharma.com
Country
China
ProdList
230
Advantage
58
JIANGYIN RUISHIPHARM CO.,LIMITED
Tel
0510-0510-66227179 18921203887
Fax
+86-0510-66227179 QQ:2200317867
Email
sales@ruishipharm.com
Country
China
ProdList
749
Advantage
58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
6059
Advantage
65
Shanghai Taijilin Industrial Co., Ltd.
Tel
021-50630626 18964684208
Fax
021-50563898
Email
kate@tajilin.com
Country
China
ProdList
1291
Advantage
58
Ningbo Fuhe Chemical Co., Ltd.
Tel
0574-1806900 18069001216
Email
nbfjj@126.com
Country
China
ProdList
100
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2806
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Beijing Eternalchem Co,. Ltd.
Tel
010-59484199 18611897322
Email
sales@eternalchem.com
Country
China
ProdList
4383
Advantage
60
Nan Jing Dirise Chemcial Co.,LTD
Tel
025-52161033 15312098939
Fax
025-83254025
Email
sales@njdrschem.com
Country
China
ProdList
583
Advantage
64
Nanjing Lynsci Chemical Co., Ltd
Tel
+86-025-83208253 +86-13851694729
Fax
0086-25-83208253
Email
layefe@163.com
Country
China
ProdList
231
Advantage
62
shanghai Rainbow MediTech.Co.Ltd.
Tel
021-64968085,64968086-5815,5812; 13472757003
Fax
+86 21 64968087
Email
xiaoxia.zeng@rainbowpharma.cn
Country
China
ProdList
961
Advantage
65
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Shenyang Comrade Chemical Co., Ltd.
Tel
+86(24) 31938773(O)
Fax
qq:174941352
Email
sales@co-chem.com
Country
China
ProdList
225
Advantage
62
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
China Shenyang Tyschem CO. ,LTD
Tel
+86-024-83607930; 18640359690
Fax
024-83607930
Email
sales@honghuchem.com
Country
China
ProdList
256
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
More
Less

View Lastest Price from 5-Bromo-2-fluoropyridine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Bromo-2-fluoropyridine 766-11-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-15
Shaanxi Dideu New Materials Co. Ltd
Product
5-Bromo-2-fluoropyridine 766-11-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KGS
Release date
2025-05-29
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Fluoro-5-bromopyridine 766-11-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-02

766-11-0, 5-Bromo-2-fluoropyridineRelated Search:

2-Fluoropyridine 1-Hexadecylpyridinium bromide 3-Bromoanisole 2,6-Lutidine Ethyl bromodifluoroacetate 4-Bromobenzotrifluoride 4-BROMO-2-FLUOROPYRIDINE 97%,4-BROMO-2-FLUOROPYRIDINE 2-Fluoro-6-methylpyridine 5-Chloro-2-fluoropyridine 2-Fluoropyridine-6-carboxylic acid 2-Fluoro-3-nitropyridine 5-Bromo-2-fluoro-4-methyl-pyridine 5-Chloro-2-fluoro-3-methylpyridine 2-CHLORO-6-FLUOROPYRIDINE 3-Bromo-2-fluoro-5-methylpyridine 2-Fluoro-3-methylpyridine 3-Amino-2-fluoropyridine 3-Chloro-2-fluoro-pyridine

  • 5-BROMO-2-FLUOROPYRIDINE
  • 3-BROMO-6-FLUOROPYRIDINE
  • 2-FLUORO-5-BROMO PYRIDINE
  • 3-fluoro-5-bromopyridine
  • 5-Bromo-2-fluoropyridine,98%
  • 2-FLUORO-5-BORMOPYRIDINE
  • 5-BROMO-2-FLUOROPYRIDINE 99%
  • 5-BROMO-2-FLUO
  • 5-BroMo-2-fluoropyridine, 99% 5GR
  • 5-Bromo-2-fluoropyridine,99%
  • 2-Fluoro-5-bromopyri
  • - 5-2 - fluorine broMine pyridine
  • 2-Fluoro-5-bromopyridine 5-Bromo-2-fluoropyridine
  • 2--5-pyridyl broMidefluoride
  • 5-Bromo-2-fluoropyridine&gt
  • Pyridine, 5-bromo-2-fluoro-
  • 2-Fluoro-5-bromopyridine ISO 9001：2015 REACH
  • 5-Brom-2-fluorpyridin
  • 2-FLUORO 5-BROMOPYRIDINE (AS PER INVOICE
  • 2-Floro-5-Bromo Pyridine
  • 5-Bromo-2-fluoropyridine, 95%
  • 766-11-0
  • Fluoropyridines
  • Bromopyridines
  • Halopyridines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines
  • Variety of halogenated heterocyclic series
  • Halogenated
  • Organohalides
  • Bromopyridines
  • Fluoropyridines
  • Halopyridines
  • Boronic Acid
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Fluorine series
  • Pyridine Series
  • blocks
  • Bromides
  • Pyridines
  • Pyridine
  • pharmacetical
  • Pyridines derivates
  • Fluorin-contained pyridine series