ChemicalBook > CAS DataBase List > 5-Bromo-2-fluoropyridine
5-Bromo-2-fluoropyridine
- Product Name
- 5-Bromo-2-fluoropyridine
- CAS No.
- 766-11-0
- Chemical Name
- 5-Bromo-2-fluoropyridine
- Synonyms
- 5-BROMO-2-FLUOROPYRIDINE;5-Brom-2-fluorpyridin;3-BROMO-6-FLUOROPYRIDINE;5-BROMO-2-FLUO;2-Fluoro-5-bromopyri;2-FLUORO-5-BORMOPYRIDINE;3-fluoro-5-bromopyridine;2-FLUORO-5-BROMO PYRIDINE;5-Bromo-2-fluoropyridine>Pyridine, 5-bromo-2-fluoro-
- CBNumber
- CB0344067
- Molecular Formula
- C5H3BrFN
- Formula Weight
- 175.99
- MOL File
- 766-11-0.mol
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5-Bromo-2-fluoropyridine Property
- Boiling point:
- 162-164 °C750 mm Hg(lit.)
- Density
- 1.71 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.5325(lit.)
- Flash point:
- 165 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- -2.79±0.10(Predicted)
- form
- Liquid
- color
- Clear colorless yellow
- Specific Gravity
- 1.710
- BRN
- 1363171
- InChIKey
- MYUQKYGWKHTRPG-UHFFFAOYSA-N
- CAS DataBase Reference
- 766-11-0(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37-37/39
- RIDADR
- UN2810
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29339900
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 520438
- Product name
- 5-Bromo-2-fluoropyridine
- Purity
- 99%
- Packaging
- 5g
- Price
- $12.48
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2705
- Product name
- 5-Bromo-2-fluoropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $106
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2705
- Product name
- 5-Bromo-2-fluoropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $275
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L19537
- Product name
- 5-Bromo-2-fluoropyridine, 98%
- Packaging
- 5g
- Price
- $92.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L19537
- Product name
- 5-Bromo-2-fluoropyridine, 98%
- Packaging
- 25g
- Price
- $314.65
- Updated
- 2024/03/01
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5-Bromo-2-fluoropyridine Chemical Properties,Usage,Production
Description
5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.
Chemical Properties
5-Bromo-2-fluoropyridine is a colourless or yellowish liquid compound with a density of 1.71 g/cm3 at 25° C; boiling point of 162-164° C (lit.) at 750 mmHg; stored at room temperature.
Uses
5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.
5-Bromo-2-fluoropyridine Preparation Products And Raw materials
Raw materials
Hexane
N,N-Dimethylformamide
Potassium hydroxide
Hydrogen peroxide
Ethyl acetate
2-Amino-5-bromopyridine
Tetrabutylammonium fluoride
Sulfuric acid
Preparation Products
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View Lastest Price from 5-Bromo-2-fluoropyridine manufacturers
hebei hongtan Biotechnology Co., Ltd
- Product
- 2-Fluoro-5-bromopyridine 766-11-0
- Price
- US $30.00-20.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 1000kg
- Release date
- 2024-03-18
Henan Fengda Chemical Co., Ltd
- Product
- 5-Brom-2-fluorpyridin 766-11-0
- Price
- US $6.00-0.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-24
BTC Nantong Pharmaceuticals Technology Co.,Ltd
- Product
- 2-Fluoro-5-bromopyridine 766-11-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Kgs
- Release date
- 2022-08-19
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