ChemicalBook > CAS DataBase List > (BOC-AMINOOXY)ACETIC ACID
(BOC-AMINOOXY)ACETIC ACID
- Product Name
- (BOC-AMINOOXY)ACETIC ACID
- CAS No.
- 42989-85-5
- Chemical Name
- (BOC-AMINOOXY)ACETIC ACID
- Synonyms
- BOC-AOA;BOC-AOA-OH;BOC-AOAC-OH;BOC-(NHOAC)-OH;BOC-NH-O-CH2COOH;RARECHEM EM WB 0063;N-Boc-(carboxymethox;T-BOC-AMINOOXYACETIC ACID;(BOC-AMINOOXY)ACETIC ACID;BOC-3-(AMINOOXY)ACETIC ACID
- CBNumber
- CB0356387
- Molecular Formula
- C7H13NO5
- Formula Weight
- 191.18
- MOL File
- 42989-85-5.mol
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(BOC-AMINOOXY)ACETIC ACID Property
- Melting point:
- ~115 °C (dec.)
- Density
- 1.214±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in methanol.
- pka
- 2.97±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- BRN
- 6137646
- InChI
- InChI=1S/C7H13NO5/c1-7(2,3)13-6(11)8-12-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
- InChIKey
- QBXODCKYUZNZCY-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CONC(OC(C)(C)C)=O
- CAS DataBase Reference
- 42989-85-5(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 8.51017
- Product name
- Boc-amino-oxyacetic acid
- Purity
- Novabiochem?
- Packaging
- 1g
- Price
- $75.1
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.51017
- Product name
- Boc-amino-oxyacetic acid
- Purity
- Novabiochem?
- Packaging
- 5G
- Price
- $305
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 15035
- Product name
- (Boc-aminooxy)acetic acid
- Purity
- ≥98.0% (T)
- Packaging
- 5g
- Price
- $238.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 15035
- Product name
- (Boc-aminooxy)acetic acid
- Purity
- ≥98.0% (T)
- Packaging
- 1g
- Price
- $255
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B3338
- Product name
- [(tert-Butoxycarbonyl)aminooxy]acetic Acid
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $17
- Updated
- 2024/03/01
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(BOC-AMINOOXY)ACETIC ACID Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
(Boc-aminooxy)acetic acid was employed to introduce a hydroxylamine moiety into peptides; reaction with an aldehyde to an oxime. It was used in the preparation of Boc-aminooxy tetra(ethylene glycol).
Uses
(Boc-aminooxy)acetic acid was used in the preparation of Boc-aminooxy tetra(ethylene glycol).
Uses
A Boc-protected bifunctional linking reagent
Synthesis
(Boc-aminooxy)acetic acid is prepared by the reaction of Di-tert-butyl dicarbonate and Aminooxyacetic acid. The specific synthesis steps are as follows:
A 500 mL round-bottom flask was charged with a suspension of aminooxyacetic acid (4 g, 36.6 mmol) in CH2Cl2 (100 mL).
The solution was cooled to 0° C. and triethylamine (16 mL, 114 mmol) was added dropwise while stiffing to dissolve all solids.
To this mixture was added a solution of di-tert-butyl dicarbonate (12 g, 55 mmol) in CH2Cl2 (20 mL).
The reaction was stirred for 30 min at 0° C., then continued for 1 h at rt.
The solution was washed with three 100 mL portions of water.
The aqueous portion was combined and extracted with two 100 mL portions of EtOAc; this EtOAc was discarded.
The pH of the aqueous portion was adjusted to 3.5 with 1 M HCl, then extracted with five 50 mL portions of EtOAc, adjusting to maintain pH 3.5 as needed.
The combined EtOAc was dried over Na2SO4, filtered, and the solvent removed in vacuo to afford a white crystalline powder (5.8 g, 83percent). TLC: (MeOH:CH2Cl2, 1:9) Rf=0.08. 1H NMR (400 MHz, CD3OD): δ 1.48 (s, 9H), 4.47 (s, 2H), 7.94 (s, 1H).
13C NMR (100 MHz, CD OD): δ, 27.1, 47.0, 72.3, 81.4, 157.8, 171.3.
Solubility in organics
Soluble in DCM, THF, DMF and DMSO
(BOC-AMINOOXY)ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (BOC-AMINOOXY)ACETIC ACID manufacturers
Xiamen Yunfan Biotech Co.,Ltd.
- Product
- Boc-AOATert-Boc-aminooxyacetic acid 42989-85-5
- Price
- US $0.00-0.00/g
- Min. Order
- 100g
- Purity
- 98%
- Supply Ability
- 1000kg/Month
- Release date
- 2024-05-14
Henan Aochuang Chemical Co.,Ltd.
- Product
- (BOC-AMINOOXY)ACETIC ACID 42989-85-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- (BOC-AMINOOXY)ACETIC ACID 42989-85-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
42989-85-5, (BOC-AMINOOXY)ACETIC ACIDRelated Search:
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