AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]

Product Name: AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]
CAS No.: 9001-66-5
Chemical Name: AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]
Synonyms: AOC3;SSAO;KAOD;Renalase;Tyraminase;VAP-1 human;MAO (enzyme);E.C. 1.4.3.4;TYRAMINE OXIDASE;Spermine oxidase
CBNumber: CB0445553
Molecular Formula: C7H15N2O6P
Formula Weight: 254.177561
MOL File: 9001-66-5.mol

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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Property

Density: 0.319[at 20℃]
vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
form: lyophilized powder
color: White to off-white
biological source: human
Water Solubility: 102g/L at 30℃
InChI: InChI=1/C7H15N2O6P/c8-5(7(11)12)2-1-3-9-6(10)4-16(13,14)15/h5H,1-4,8H2,(H,9,10)(H,11,12)(H2,13,14,15)/t5-/s3
InChIKey: FCIHAQFHXJOLIF-GQMHJJTINA-N
SMILES: C(O)(=O)[C@@H](N)CCCNC(CP(O)(O)=O)=O |&1:3,r|
LogP: -3 at 23℃
CAS DataBase Reference: 9001-66-5

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Safety

Safety Statements: 23-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP3295
Product name: VAP-1 human
Purity: recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
Packaging: 10μG
Price: $367
Updated: 2025/07/31

Sigma-Aldrich

Product number: SRP6241
Product name: VAP-1 human
Purity: recombinant, expressed in CHO cells, ≥95% (SDS-PAGE)
Packaging: 10μG
Price: $363
Updated: 2024/03/01

Usbiological

Product number: 028151
Product name: Spermine Oxidase
Packaging: 96Tests
Price: $864
Updated: 2021/12/16

Usbiological

Product number: 028152
Product name: Spermine Oxidase
Packaging: 96Tests
Price: $879
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb531122
Product name: AOC3
Packaging: 10μg
Price: $1246.1
Updated: 2021/12/16

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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Chemical Properties,Usage,Production

Uses

Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions[1][2].

Definition

An enzyme that is distributedwidely among animals. It inactivates a number ofbiogenic amines by catalyzing the oxidative deam-ination of these compounds.

Flammability and Explosibility

Not classified

Biological Activity

The protein VAP-1 (vascular adhesion protein-1) belongs to the group of semicarbazide sensitive amine oxidases (SSAO) th at catalyze the formation of reactive oxygen species. It is a unique adhesion molecule th at participates in inflammatory leukocyte recruitment in blood vessels. It functions in leukocyte extravasation to inflamed tissues. In the human eye, it has been associated with ocular inflammatory diseases, such as uveitis, age-related macular degeneration, and diabetic retinopathy. Its expression has been observed to be altered in several diseases, such as rheumatoid arthritis, diabetes, and atherosclerosis.

References

[1] Shih JC, et al. Monoamine oxidase: from genes to behavior. Annu Rev Neurosci. 1999;22:197-217. DOI:10.1146/annurev.neuro.22.1.197
[2] Bortolato M, et al. Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1527-33. DOI:10.1016/j.addr.2008.06.002
[3] Youdim MB, et al. The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci. 2006 Apr;7(4):295-309. DOI:10.1038/nrn1883

AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Preparation Products And Raw materials

Raw materials

Preparation Products

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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Suppliers

China 74 Germany 1 Switzerland 1 United States 5 Global 81

Shanghai Baoman Biotechnology Co., Ltd.

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Syncozymes (Shanghai) Co.,Ltd.

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Nanjing Dulai Biotechnology Co., Ltd.

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Nanjing Sunlida Biological Technology Co., Ltd.

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Shanghai Macklin Biochemical Co.,Ltd.

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9001-66-5, AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]Related Search:

Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) METHYL ISOCYANOACETATE Tosylmethyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE PHENYLSELENOL 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Ferric acetylacetonate Cupric acetylacetonate COBALT(II) ACETYLACETONATE SALCOMINE Aluminum acetylacetonate Ethyl isocyanoacetate Benzyl isocyanide

AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]

TYRAMINE OXIDASE

PLASMA AMINE OXIDASE FROM BOVINE PLASMA;PAO

amine oxidase, flavin-containing

plasma amine oxidase from bovine plasma

tyramine oxidase from arthrobacter*species

Oxidase, monoamine

YRAMINE OXIDASE FROM ARTHROBACTER &

tyramine oxidase from arthrobacter sp.

SSAO

AOC3

VAP-1 human

Epinephrine oxidase

Flavin amine oxidase

MAO (enzyme)

Monoamine oxygenase

N1,N12-Diacetylspermine oxidase

Renalase

Serotonin deaminase

Spermidine oxidase

Spermine oxidase

Tryptamine oxidase

Tyraminase

E.C. 1.4.3.4

KAOD

Monoamine Oxidase Activity Microplate Assay Kit

9001-66-5

BioChemical

General Metabolic Enzymes I-Z

General Metabolic Enzymes

Metabolomics