ChemicalBook > CAS DataBase List > 5-IODO-2-METHOXYANILINE

5-IODO-2-METHOXYANILINE

Product Name: 5-IODO-2-METHOXYANILINE
CAS No.: 77770-09-3
Chemical Name: 5-IODO-2-METHOXYANILINE
Synonyms: 5-IODO-O-ANISIDINE;2-amino-4-iodoanisole;5-IODO-2-METHOXYANILINE;5-iodine-2-methoxyaniline;5-Iodo-2-methoxyaniline,97%;BenzenaMine, 5-iodo-2-Methoxy-;4-Methoxy-3-amino-1-iodobenzene;2-Amino-4-iodoanisole, 5-Iodo-o-anisidine;2-AMino-4-iodoanisole[5-Iodo-2-Methoxyaniline]
CBNumber: CB0473093
Molecular Formula: C7H8INO
Formula Weight: 249.05
MOL File: 77770-09-3.mol

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5-IODO-2-METHOXYANILINE Property

Melting point:: 85-87°C
Boiling point:: 304.3±32.0 °C(Predicted)
Density: 1.807±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.58±0.10(Predicted)
Appearance: Yellow to brown Solid
Water Solubility: Sparingly soluble in water 0.87 g/L @ 25°C.
Sensitive: Light Sensitive
CAS DataBase Reference: 77770-09-3

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Safety

Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39
HS Code: 2922290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 4656-H-05
Product name: 5-Iodo-2-methoxyaniline
Purity: 98%
Packaging: 5G
Price: $141
Updated: 2021/12/16

AK Scientific

Product number: X5382
Product name: 5-iodo-2-methoxyaniline
Packaging: 5g
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0024959
Product name: 5-IODO-2-METHOXYANILINE
Purity: 95.00%
Packaging: 1G
Price: $654.89
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0024959
Product name: 5-IODO-2-METHOXYANILINE
Purity: 95.00%
Packaging: 5G
Price: $965.35
Updated: 2021/12/16

Abosyn

Product number: 61-3212
Product name: 2-Amino-4-iodoanisole
Purity: 95+%
Packaging: 1g
Price: $45
Updated: 2021/12/16

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5-IODO-2-METHOXYANILINE Chemical Properties,Usage,Production

Uses

5-Iodo-2-methoxyaniline is used as a pharmaceutical intermediate.

Synthesis

52692-09-8

77770-09-3

GENERAL STEPS: To a dry round-bottomed flask fitted with a magnetic stirrer, a mixed solution of ethanol (75 mL) and ethyl acetate (30 mL) of 4-iodo-2-nitroanisole (16.2 g, 58 mmol) and tin(II) chloride dihydrate (65.5 g, 290 mmol) was added under nitrogen protection. The reaction mixture was heated and stirred at 70°C for 30 minutes. Subsequently, about half of the solvent was removed by evaporation and ether (100 mL) was added. The mixture was allowed to stand overnight in a refrigerator. The precipitate precipitated was collected by filtration and washed with ether. The resulting solid was dissolved in 15% aqueous sodium hydroxide solution (150 mL) and cooled in an ice bath. The mixture was extracted with dichloromethane, and the organic layer was sequentially washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give 5-iodo-2-methoxyaniline (9.5 g, 38 mmol, 66% yield) as a white solid.

References

[1] Synlett, 2012, vol. 23, # 8, p. 1205 - 1208
[2] Synlett, 2013, vol. 24, # 14, p. 1772 - 1776
[3] Russian Chemical Bulletin, 2013, vol. 62, # 4, p. 1103 - 1110
[4] Izv. Akad. Nauk, Ser. Khim., 2013, # 4, p. 1102 - 1110,9
[5] Journal of the Chemical Society, 1916, vol. 109, p. 1087

5-IODO-2-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-IODO-2-METHOXYANILINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-IODO-2-METHOXYANILINE 77770-09-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-IODO-2-METHOXYANILINE 77770-09-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-IODO-2-METHOXYANILINE 77770-09-3
Price: US $1.00/g
Min. Order: 1g
Purity: 96%-98%
Supply Ability: 1000KGS
Release date: 2019-12-24

77770-09-3, 5-IODO-2-METHOXYANILINERelated Search:

5-IODO-2-METHOXYANILINE 4-Iodo-2-nitroanisole 4-Iodoanisole 2-iodo-4-methoxyaniline 6-IODO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE 3-IODO-5-METHOXYANILINE 4-IODO-3-METHOXYANILINE HYDROCHLORIDE 3-IODO-4-METHOXYANILINE HYDROCHLORIDE,3-Iodo-4-methoxyaniline HCl 2-Iodo-3-methoxyaniline 4-Iodo-2-methoxyaniline 2-IODO-5-METHOXYANILINE 3-IODO-4-METHOXYANILINE,3-Iodo-p-anisidine BUTTPARK 120\07-78 3-(4-FLUOROBENZOYL)-5,7-DIIODO-1,3-BENZOXAZOL-2(3H)-ONE 6-IODO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE 5,7-DIIODO-1,3-BENZOXAZOL-2(3H)-ONE 5,7-DIIODO-3-[4-(TRIFLUOROMETHYL)BENZOYL]-1,3-BENZOXAZOL-2(3H)-ONE 5,7-DIIODO-3-(4-METHOXYBENZOYL)-1,3-BENZOXAZOL-2(3H)-ONE

5-Iodo-2-methoxyaniline,97%

5-IODO-2-METHOXYANILINE

5-IODO-O-ANISIDINE

2-amino-4-iodoanisole

BenzenaMine, 5-iodo-2-Methoxy-

2-Amino-4-iodoanisole, 5-Iodo-o-anisidine

2-AMino-4-iodoanisole[5-Iodo-2-Methoxyaniline]

4-Methoxy-3-amino-1-iodobenzene

5-iodine-2-methoxyaniline

77770-09-3

7770-09-3

C7H8INO