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CORTEXOLONE

Product Name
CORTEXOLONE
CAS No.
152-58-9
Chemical Name
CORTEXOLONE
Synonyms
11-DEOXYCORTISOL;CORTODOXONE;Deoxycortisol;11-DESOXYCORTISOL;11-deoxyhydrocortisone;11-desoxyhydrocortisone;17,21-DIHYDROXYPROGESTERONE;17-hydroxy-11-deoxycorticosterone;11-DEOXY-17-HYDROXYCORTICOSTERONE;4-Pregnene-17a,21-diol-3,20-dione
CBNumber
CB0493958
Molecular Formula
C21H30O4
Formula Weight
346.46
MOL File
152-58-9.mol
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CORTEXOLONE Property

Melting point:
205-208 °C
Boiling point:
401.19°C (rough estimate)
Density 
1.22±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
120 ° (C=1, Dioxane)
Flash point:
9℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
Dioxane (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
12?+-.0.60(Predicted)
color 
White to Off-White
Water Solubility 
44.08mg/L(37 ºC)
Merck 
14,2932
InChIKey
WHBHBVVOGNECLV-OBQKJFGGSA-N
CAS DataBase Reference
152-58-9(CAS DataBase Reference)
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
24/25-22-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
TU5011500
HS Code 
2937.23.5050
Toxicity
mouse,LD50,intravenous,100mg/kg (100mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04684,
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R200050
Product name
17-ALPHA,21-DIHYDROXYPREGN-4-ENE-3,20-DIONE
Purity
AldrichCPR
Packaging
1MG
Price
$29.8
Updated
2024/03/01
Sigma-Aldrich
Product number
R0500
Product name
Reichstein’s substance S
Purity
≥98%
Packaging
1g
Price
$59.2
Updated
2024/03/01
Sigma-Aldrich
Product number
D-061
Product name
11-Deoxycortisol solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$142
Updated
2024/03/01
TCI Chemical
Product number
C1478
Product name
Cortexolone
Purity
>98.0%(HPLC)
Packaging
1g
Price
$108
Updated
2024/03/01
TRC
Product number
D232600
Product name
11-DeoxyCortisol
Packaging
25mg
Price
$105
Updated
2021/12/16
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CORTEXOLONE Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

11-Deoxy Cortisol (Hydrocortisone EP Impurity F) is a glucocorticoid receptor binding.

Definition

ChEBI: 11-deoxycortisol is a deoxycortisol that is cortisol in which the hydroxy group at position 11 has been replaced by a hydrogen. It has a role as a mouse metabolite and a human metabolite. It is a glucocorticoid, a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone and a deoxycortisol.

CORTEXOLONE Preparation Products And Raw materials

Raw materials

Preparation Products

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CORTEXOLONE Suppliers

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View Lastest Price from CORTEXOLONE manufacturers

Henan Fengda Chemical Co., Ltd
Product
CORTEXOLONE 152-58-9
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
CORTEXOLONE 152-58-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
CORTEXOLONE 152-58-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-24

152-58-9, CORTEXOLONERelated Search:

Hydrocortisone acetate CORTISOL-9,11,12,12-D4 Hydrocortisone sodium succinate Hydrocortisone 21-hemisuccinate Cortexolone 21-acetate,CORTEXOLONE ACETATE 11-ALPHA-HYDROCORTISONE CORTEXOLONE CORTISONE Flurandrenolide 6BETA-HYDROXYCORTISOL Cortisone acetate Hydrocortisone Hydrocortisone-17-butyrate Hydrocortisone sodium phosphate CORTISOL 17-VALERATE 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE 4-PREGNEN-17,21-DIOL-3,11,20-TRIONE 21-GLUCOSIDURONATE 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE

  • (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
  • Hydrocortisone Impurity 6（Hydrocortisone EP Impurity F）
  • 11-DEOXYCORTISOL; CORTEXOLONE; REICHSTEIN'S SUBSTANCE S
  • 11-dioxy-cortiso
  • 11-dioxycortisol
  • 17,21-dihydroxy-pregn-4-ene-20-dione
  • 17-hydroxy-11-deoxycorticosterone
  • nsc-18317
  • CORTODOXONE
  • CORTEXOLONE
  • 17ALPHA,21-DIHYDROXY-4-PREGNENE-3,20-DIONE
  • 17ALPHA,21-DIHYDROXYPREGNA-4-ENE-3,20-DIONE
  • 11-DEOXY-17-HYDROXYCORTICOSTERONE
  • 11-DEOXYCORTISOL
  • 11-DESOXY-17-HYDROXYCORTICOSTERONE
  • 11-DESOXYCORTISOL
  • Reichstein S
  • 11-Deoxy-17-hydroxycorticosterone, 11-Deoxycortisol, 17α,21-Dihydroxy-4-pregnene-3,20-dione, 17α-Hydroxycortexone, 17,21-Dihydroxy-4-pregnene-3,20-dione, 17,21-Dihydroxyprogesterone, 4-Pregnene-17α,21-diol-3,20-dione, Cortexolone, Reichsteins Compound S
  • ReichsteinSubstanceS
  • 17α,21-Dihydroxypregn-4-ene-3,20-dione
  • Cortexolone,99%
  • Reichstein’s substanceS,11-Deoxy-17-hydroxycorticosterone, 11-Deoxycortisol, 17α,21-Dihydroxy-4-pregnene-3,20-dione, 17α-Hydroxycortexone, 17,21-Dihydroxy-4-pregnene-3,20-dione, 17,21-Dihydroxyproges
  • 11-Deoxy-17-hydroxycorticosterone 17alpha,21-Dihydroxy-4-pregnene-3,20-dione Reichstein's Substance S
  • 4-Pregnen-17a,21-diol-3,20-dione-d2
  • Pregn-4-ene-3,20-dione, 17,21-dihydroxy-
  • 11-Deoxycortisol solution
  • cortexolone solution,100ppm
  • 17α-Hydroxycortexone
  • 4-Pregnene-17α,21-diol-3,20-dione
  • Hydrocortisone impurity F (EP)
  • Hydrocortisone EP Impurity F
  • 11-deoxyhydrocortisone
  • 11-desoxyhydrocortisone
  • 17ALPHA-HYDROXYCORTEXONE
  • 17,21-DIHYDROXY-4-PREGNENE-3,20-DIONE
  • 17,21-DIHYDROXYPROGESTERONE
  • 4-PREGNENE-17ALPHA,21-DIOL-3,20-DIONE
  • 4-PREGNEN-17,21-DIOL-3,20-DIONE
  • 4-PREGNEN-17A 21-DIOL-3,20-DIONE
  • 4-PREGNEN-17ALPHA,21-DIOL-3,20-DIONE
  • (8R,9S,10R,13S,14S,17R)-17-HYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
  • REICHSTEIN'S COMPOUND ''S''
  • REICHSTEIN'S SUBSTANCE S
  • REICHSTEIN'S SUBSTANCE ''S''
  • REICHSTEIN'S SUBSTANCE 'S'
  • skf3050
  • 11-Desoxycortisone
  • 17alpha,21-Dihydroxypregn-4-ene-3,20-dione
  • 17,21-Dihydroxypregn-4-en-3,20-dione
  • 4-Pregnene-17a,21-diol-3,20-dione
  • 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • Deoxycortisol
  • Cortexolone &gt
  • 17,21-Dihydroxypregn-4-ene-3,20-dio
  • Hydrocortisone EP Impurity F (Reichsteins Substance S)
  • (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-
  • 152-58-9 CORTEXOLONE
  • 17α,21-dihydroxyprogesterone