3-(Trifluoromethyl)benzylamine

Product Name: 3-(Trifluoromethyl)benzylamine
CAS No.: 2740-83-2
Chemical Name: 3-(Trifluoromethyl)benzylamine
Synonyms: [3-(TRIFLUOROMETHYL)PHENYL]METHANAMINE;RARECHEM AL BW 0022;TIMTEC-BB SBB006691;3-(Trifluoromethyl)b;M-TRIFLUOROMETHYL BENZYLAMINE;3-(TRIFLUOROMETHYL)BENZYLAMINE;3-(Trifluoromethyl)benzylamine98%;3-(Trifluoromethyl)benzylamine 98%;3-(Trifluoromethyl)benzylamine, 97+%;3-(Trifluoromethyl)benzenemethanamine
CBNumber: CB0665638
Molecular Formula: C8H8F3N
Formula Weight: 175.15
MOL File: 2740-83-2.mol

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3-(Trifluoromethyl)benzylamine Property

Melting point:: 176.5-178.5 °C
Boiling point:: 93-97 °C (22 mmHg)
Density: 1.222 g/mL at 25 °C(lit.)
refractive index: n20/D 1.463(lit.)
Flash point:: 160 °F
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 8.69±0.10(Predicted)
form: Liquid
Specific Gravity: 1.222
color: Clear colorless to yellow
Water Solubility: insoluble
Sensitive: Air Sensitive
BRN: 1102465
InChI: InChI=1S/C8H8F3N/c9-8(10,11)7-3-1-2-6(4-7)5-12/h1-4H,5,12H2
InChIKey: YKNZTUQUXUXTLE-UHFFFAOYSA-N
SMILES: C1(CN)=CC=CC(C(F)(F)F)=C1
CAS DataBase Reference: 2740-83-2(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 22-34
Safety Statements: 26-36/37/39-45
RIDADR: UN 2735 8/PG 3
WGK Germany: 2
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: III
HS Code: 29214980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 263494
Product name: 3-(Trifluoromethyl)benzylamine
Purity: 98%
Packaging: 5g
Price: $67.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 263494
Product name: 3-(Trifluoromethyl)benzylamine
Purity: 98%
Packaging: 25g
Price: $221
Updated: 2025/07/31

TRC

Product number: T896668
Product name: 3-(Trifluoromethyl)benzylamine
Packaging: 500mg
Price: $60
Updated: 2021/12/16

TRC

Product number: T896668
Product name: 3-(Trifluoromethyl)benzylamine
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 007603
Product name: 3-(Trifluoromethyl)benzylamine
Purity: 98%
Packaging: 25g
Price: $45
Updated: 2021/12/16

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3-(Trifluoromethyl)benzylamine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellowish liquid

Uses

3-(Trifluoromethyl)benzylamine has been used in the preparation of 6-substituted purines.

Synthesis

402-23-3

227616-77-5

2740-83-2

437761-03-0

Synthesis of (6S)-3-{[(benzyloxy)carbonyl][3-(trifluoromethyl)benzyl]amino}-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-A]pyrimidine-6-carboxylic acid from 3-(trifluoromethyl)benzyl bromide and (S)-3-(((benzyloxy)carbonyl)amino)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine -6-carboxylic acid (12a) was performed in the following general steps: to a mixture of acid 1i (4.50 g, 13.7 mmol) in 70 mL THF at 0 °C was added 3-(trifluoromethyl)benzyl bromide (8.35 mL, 54.7 mmol), NaH (60% dispersed in oil, 1.64 g, 41.4 mmol) and TBAI (100 mg, catalytic amount). The reaction mixture was stirred at room temperature for 15 h. The reaction was then quenched by the addition of 50 mL of H2O. The volatile solvent was removed by rotary evaporation and the resulting aqueous solution was partitioned with Et2O. The organic phase was extracted with 20% saturated NaHCO3 solution (3 times). The combined organic extracts were acidified with 1N HCl and extracted with EtOAc (5 times). The combined organic extracts were washed with brine, dried (Na2SO4), and concentrated to give 6.18 g (93% yield) of 3-(trifluoromethyl)benzylamine (12a), a product that could be used in the next step without further purification.

References

[1] Patent: US2003/64962, 2003, A1

3-(Trifluoromethyl)benzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(Trifluoromethyl)benzylamine Suppliers

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View Lastest Price from 3-(Trifluoromethyl)benzylamine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-(Trifluoromethyl)benzylamine 2740-83-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-(Trifluoromethyl)benzylamine 2740-83-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 3-(Trifluoromethyl)benzylamine 2740-83-2
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-09

2740-83-2, 3-(Trifluoromethyl)benzylamineRelated Search:

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3-(Trifluoromethyl)benzylamine 98%

3-(Trifluoromethyl)benzylamine98%

Benzenemethanamine, 3-(trifluoromethyl)-

1-[3-(trifluoromethyl)phenyl]methanamine

3-(Trifluoromethyl)benzenemethanamine

3-(Trifluoromethyl)b

3-(Aminomethyl)benzotrifluoride, [3-(Trifluoromethyl)phenyl]methylamine

3-(TrifluoroMethyl)benzylaMine, 98% 5GR

M-TRIFLUOROMETHYL BENZYLAMINE

TIMTEC-BB SBB006691

RARECHEM AL BW 0022

[3-(TRIFLUOROMETHYL)PHENYL]METHANAMINE

3-(TRIFLUOROMETHYL)BENZYLAMINE

3-(TRIFLUOROMETHYL)-BENZYLAMINE FOR SYNT

3-(Trifluoromethyl)benzylamine, 97+%

[3-(trifluoromethyl)phenyl]methylammonium

2740-83-2

C8H9F3N

AMINE

C8

Amines

Building Blocks

Nitrogen Compounds

Organic Building Blocks

Fluorine series

Anilines, Aromatic Amines and Nitro Compounds

Amine

Amines

C8

Nitrogen Compounds