ChemicalBook > CAS DataBase List > 2-Iodobenzoic acid

2-Iodobenzoic acid

Product Name
2-Iodobenzoic acid
CAS No.
88-67-5
Chemical Name
2-Iodobenzoic acid
Synonyms
O-IODOBENZOIC ACID;2-IODO BENZONIC ACID;NSC 3772;usafek-572;USAF ek-572;'LGC' (4009);O-iodine acid;IodobenzoicAcid;2-lodhenxoieacid;2-iodo-benzoicaci
CBNumber
CB1126640
Molecular Formula
C7H5IO2
Formula Weight
248.02
MOL File
88-67-5.mol
More
Less

2-Iodobenzoic acid Property

Melting point:
160-162 °C(lit.)
Boiling point:
313.9±25.0 °C(Predicted)
Density 
2.25
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in dimethyl sulfoxide and methanol
pka
2.85(at 25℃)
form 
Powder, Crystals or Flakes
color 
Light yellow to orange-brown
Water Solubility 
sparingly soluble
Sensitive 
Light Sensitive
Merck 
14,5030
BRN 
1861406
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey
CJNZAXGUTKBIHP-UHFFFAOYSA-N
CAS DataBase Reference
88-67-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2-iodo-(88-67-5)
EPA Substance Registry System
Benzoic acid, 2-iodo- (88-67-5)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-36/37/38-20/21/22
Safety Statements 
26-39-24/25-22-36
WGK Germany 
3
RTECS 
DH2975000
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, LIGHT SENSITIVE
HS Code 
29163900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I7675
Product name
2-Iodobenzoic acid
Purity
98%
Packaging
25g
Price
$28.4
Updated
2024/03/01
Sigma-Aldrich
Product number
418463
Product name
2-Iodobenzoic acid
Purity
≥99%, purified by sublimation
Packaging
1G
Price
$34.6
Updated
2023/01/07
TCI Chemical
Product number
I0053
Product name
2-Iodobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
I0053
Product name
2-Iodobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
A10563
Product name
2-Iodobenzoic acid, 98+%
Packaging
25g
Price
$23.65
Updated
2024/03/01
More
Less

2-Iodobenzoic acid Chemical Properties,Usage,Production

Description

2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.

Chemical Properties

white crystal powder. Soluble in alcohol and ether, insoluble in water.

Uses

Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.

Preparation

2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.

Definition

ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.

Synthesis Reference(s)

Journal of the American Chemical Society, 93, p. 4841, 1971 DOI: 10.1021/ja00748a029

Purification Methods

Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1030.]

2-Iodobenzoic acid Preparation Products And Raw materials

Raw materials

Anthranilic acid

Preparation Products

2-IODOBENZOYL CHLORIDE Dess-Martin periodinane 2-Iodoxybenzoic acid 2'-IODOHIPPURIC ACID Flufenamic acid 2-Ethoxycarbonylphenylboronic acid pinacol ester
More
Less

2-Iodobenzoic acid Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 482 Europe 3 France 2 Germany 9 India 66 Japan 5 Poland 1 Slovakia 1 South Korea 2 Switzerland 1 The Netherlands 1 Ukraine 2 United Kingdom 14 United States 50 Global 645
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
RSA Corporation
Tel
--
Fax
--
Email
media@RSAgroup.ca
Country
United States
ProdList
343
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Lianyungang Ziyan Chemical Co., Ltd.
Tel
--
Fax
--
Email
ziyanchem@gmail.com
Country
United States
ProdList
360
Advantage
0
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
Labseeker Inc
Tel
--
Fax
--
Email
marketing@labseeker.com
Country
United States
ProdList
1495
Advantage
55
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Magical Scientific LLC
Tel
--
Fax
--
Country
United States
ProdList
703
Advantage
0
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Acros Organics USA
Tel
--
Fax
--
Email
eveleth@fisherchem.com
Country
United States
ProdList
3846
Advantage
81
OMKAR CHEMICALS & RESEARCH LABS..
Tel
--
Fax
--
Email
rishi@bom8.vsnl.net.in
Country
United States
ProdList
87
Advantage
51
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
MICAL specialty chemicals
Tel
--
Fax
--
Email
service@iodine.com
Country
United States
ProdList
33
Advantage
60
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
ProChem, Inc.
Tel
--
Fax
--
Email
prochem1@aol.com
Country
United States
ProdList
1691
Advantage
66
Esprit Chemical Company
Tel
--
Fax
--
Email
admin@esprixtech.com
Country
United States
ProdList
1616
Advantage
55
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Richman Chemical Inc.
Tel
--
Fax
--
Email
kac@richmanchemical.com
Country
United States
ProdList
692
Advantage
67
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
Magical Scientific LLP
Tel
--
Fax
--
Country
United States
ProdList
750
Advantage
43
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
More
Less

View Lastest Price from 2-Iodobenzoic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-Iodobenzoic acid 88-67-5
Price
US $100.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-24
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Iodobenzoic acid 88-67-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-16
Apeloa production Co.,Limited
Product
2-Iodobenzoic acid 88-67-5
Price
US $1.00/g
Min. Order
1g
Purity
0.98
Supply Ability
1000
Release date
2024-07-19

88-67-5, 2-Iodobenzoic acidRelated Search:

Salicylic acid Methyl 2-bromobenzoate o-Toluic acid Folic acid 2,4-Dichlorobenzoic acid 2-Nitrobenzoic acid Benzyl benzoate Glycine Thiosalicylic acid 2-Benzoylbenzoic acid 2,3,4-Trihydroxybenzoic acid Ethyl 2-(Chlorosulfonyl)acetate 3-HYDROXY-2,4,6-TRIIODOBENZOIC ACID Benzoic acid 2-Iodoanisole 2-Phenylphenol 2-Fluorobenzaldehyde 2-Fluorobenzoyl chloride

  • O-IODOBENZOIC ACID
  • RARECHEM AL BO 0686
  • 2-IODOBENZOIC ACID
  • 2-IODO BENZONIC ACID
  • BENZOIC ACID, 2-IODO-
  • 'LGC' (4009)
  • IODOBENZOIC-2 ACID
  • 2-IODOBENZOIC ACID pure
  • 2-(Hydroxycarbonyl)phenyliodine
  • 2-Iodobenzoic acid, 98% 100GR
  • 2-Iodobenzoic acid, 98% 25GR
  • o-Iodobenzenecarboxylic acid
  • O-iodine acid
  • NSC 3772
  • 2-Iodobenzoic Acid, 97+%
  • Adjacent iodine benzoic acid
  • 2-Iodobenzoic acid >=99%, purified by sublimation
  • 2-iodo-benzoicaci
  • Benzoic acid, o-iodo-
  • Kyselina o-jodbenzoova
  • kyselinao-jodbenzoova
  • o-iodo-benzoicaci
  • o-lodobenzoicacid
  • USAF ek-572
  • usafek-572
  • ACID O-IODOBENZOIC
  • o-Iodobenzoic Acid 2-Iodobenzoic acid
  • 2-IODOBENZOIC ACID, SUBLIMED, 99+%
  • IodobenzoicAcid
  • 2-Iodobenzoic acid, 98+%
  • ORTHO-IODOSOBENZOICACID
  • 2-IODOBENZOIC ACID 88-67-5
  • 2-IodobenzoicAcid&gt
  • 2-Iodobenzoic acid, 98%, for synthesis
  • 2-Iodobenzoic acid (Stellar-2003)
  • 2-IODOBENZOIC ACID For Synthesis
  • Aniodobenzoic acid
  • Metronidazole Impurity 16(Secnidazole)-d6
  • 2 Iodo Benzoic Acid (O-Iodobenzoic Acid)
  • 2-lodhenxoieacid
  • 2-Iodobenzoic Acid 97.5% For Synthesis
  • 88-67-5
  • 98-67-5
  • IC6H4COOH
  • 2IC6H4CO2H
  • CARBOXYLIC ACID
  • Organic Building Blocks
  • Building Blocks
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • Aromatics
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks
  • C7