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ZK 112993

Product Name
ZK 112993
CAS No.
105114-63-4
Chemical Name
ZK 112993
Synonyms
ZK 112993;11β-(4-Acetylphenyl)-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
CBNumber
CB11351975
Molecular Formula
C29H32O3
Formula Weight
428.56258
MOL File
105114-63-4.mol
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Hazard and Precautionary Statements (GHS)

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ZK 112993 Chemical Properties,Usage,Production

Uses

ZK112993 is a potent progesterone receptor (PR) antagonist. ZK112993 significantly inhibits the growth of T61 human tumors in nude mice[1].

References

[1] C A Sartorius, et al. Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP. J Biol Chem. 1993 May 5;268(13):9262-6. PMID:8387487
[2] Claudia Lanari, et al.? Antiprogestins in breast cancer treatment: are we ready? Endocr Relat Cancer. 2012 May 3;19(3):R35-50. DOI:10.1530/ERC-11-0378

ZK 112993 Preparation Products And Raw materials

Raw materials

Preparation Products

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ZK 112993 Suppliers

TargetMol Chemicals Inc.
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15002134094
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marketing@targetmol.cn
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China
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29357
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TargetMol Chemicals Inc.
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+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
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105114-63-4, ZK 112993Related Search:


  • ZK 112993
  • 11β-(4-Acetylphenyl)-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
  • 105114-63-4