ChemicalBook > CAS DataBase List > ZK 112993
ZK 112993
- Product Name
- ZK 112993
- CAS No.
- 105114-63-4
- Chemical Name
- ZK 112993
- Synonyms
- ZK 112993;11β-(4-Acetylphenyl)-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
- CBNumber
- CB11351975
- Molecular Formula
- C29H32O3
- Formula Weight
- 428.56258
- MOL File
- 105114-63-4.mol
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ZK 112993 Chemical Properties,Usage,Production
Uses
ZK112993 is a potent progesterone receptor (PR) antagonist. ZK112993 significantly inhibits the growth of T61 human tumors in nude mice[1].
References
[1] C A Sartorius, et al. Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP. J Biol Chem. 1993 May 5;268(13):9262-6. PMID:8387487
[2] Claudia Lanari, et al.? Antiprogestins in breast cancer treatment: are we ready? Endocr Relat Cancer. 2012 May 3;19(3):R35-50. DOI:10.1530/ERC-11-0378
ZK 112993 Preparation Products And Raw materials
Raw materials
Preparation Products
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ZK 112993 Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29357
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19961
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
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