4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER

Product Name: 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER
CAS No.: 1015433-96-1
Chemical Name: 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER
Synonyms: METHYL 4,5-DIFLUORO-2-NITROBENZOATE;methyl 3,4-difluoro-6-nitro benzoate;4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER;Benzoic acid, 4,5-difluoro-2-nitro-, methyl ester;4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER ISO 9001：2015 REACH
CBNumber: CB11485007
Molecular Formula: C8H5F2NO4
Formula Weight: 217.13
MOL File: 1015433-96-1.mol

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4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER Property

Melting point:: 59-63°
Boiling point:: 288℃
Density: 1.471
Flash point:: 128℃
storage temp.: Sealed in dry,Room Temperature
Appearance: White to off-white Solid
InChI: InChI=1S/C8H5F2NO4/c1-15-8(12)4-2-5(9)6(10)3-7(4)11(13)14/h2-3H,1H3
InChIKey: JHWZADUIXGMAKM-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC(F)=C(F)C=C1[N+]([O-])=O

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M303773
Product name: Methyl4,5-Difluoro-2-nitrobenzoate
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 211000
Product name: Methyl4,5-difluoro-2-nitrobenzoate
Purity: 95%
Packaging: 100mg
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: PC53622
Product name: Methyl4,5-difluoro-2-nitro-benzoate
Purity: 95%
Packaging: 5g
Price: $160
Updated: 2021/12/16

AK Scientific

Product number: X4304
Product name: 4,5-Difluoro-2-nitrobenzoicacidmethylester
Packaging: 25g
Price: $249
Updated: 2021/12/16

Apolloscientific

Product number: PC53622
Product name: Methyl4,5-difluoro-2-nitro-benzoate
Purity: 95%
Packaging: 25g
Price: $479
Updated: 2021/12/16

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4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 4,5-difluoro-2-nitrobenzoate is mainly used as an intermediate in organic synthesis.

Synthesis

67-56-1

20372-63-8

1015433-96-1

Step 2 (Ib): to a solution of anhydrous methanol (MeOH, 1.0 L) of 4,5-difluoro-2-nitrobenzoic acid (Ia, 40.0 g, 196.947 mmol) was slowly added concentrated sulfuric acid (H2SO4, 60.0 mL), and the reaction mixture immediately became clear. The reaction system was heated to reflux with continuous stirring for 2 days. After completion of the reaction, methanol was removed by rotary evaporator under reduced pressure. The residue was liquefied with ethyl acetate (EtOAc) and water and the organic phase was collected. The organic phase was sequentially washed with saturated brine and dried over anhydrous magnesium sulfate (MgSO4). After filtration, the filtrate was treated with anhydrous sodium sulfate (Na2SO4), filtered again, and the filtrate was concentrated to give methyl 4,5-difluoro-2-nitrobenzoate as a light yellow solid with a yield of 39.71 g and 93% yield.

References

[1] Patent: WO2008/36843, 2008, A2. Location in patent: Page/Page column 33

4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER Suppliers

China 70 Germany 1 India 1 United Kingdom 2 United States 6 Global 80

Apin Chemicals Limited (UK)

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Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6184
Advantage: 60

Fluorochem Ltd.

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Email: enquiries@fluorochem.co.uk
Country: United Kingdom
ProdList: 6401
Advantage: 74

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View Lastest Price from 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER manufacturers

Henan Fengda Chemical Co., Ltd

Product: Methyl 4,5-difluoro-2-nitrobenzoate 1015433-96-1
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-13

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 4,5-Difluoro-2-nitrobenzoate 1015433-96-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%+
Supply Ability: 100 tons
Release date: 2020-01-13

Career Henan Chemical Co

Product: 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER 1015433-96-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

1015433-96-1, 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTERRelated Search:

4,5-dichloro-2-nitrobenzaldehyde Dimethyl carbonate 4,5-DIFLUORO-2-NITROBENZOIC ACID ETHYL ESTER Methyl 4-fluoro-2-nitrobenzoate 4,5-Difluoro-2-nitrobenzoic acid 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER 2-Amino-5-fluorobenzoic acid methyl ester Methyl 2-amino-4,5-difluorobenzoate 5-Fluoro-2-nitrobenzoic acid 4-Fluoro-2-nitrobenzoic acid 4-FLUORO-2-NITRO-BENZALDEHYDE 2-Amino-4,5-difluorobenzoic acid 4,5-DIFLUORO-2-NITROTOLUENE 2-NITRO-5-FLUOROBENZOIC ACID, METHYL ESTER 5-Fluoro-2-nitrobenzadehyde 4-FLUORO-2-NITROBENZYL ALCOHOL

4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER

METHYL 4,5-DIFLUORO-2-NITROBENZOATE

methyl 3,4-difluoro-6-nitro benzoate

Benzoic acid, 4,5-difluoro-2-nitro-, methyl ester

4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER ISO 9001：2015 REACH

1015433-96-1

Fluorine series

Aromatic Esters