Mozavaptan Hydrochloride

Product Name: Mozavaptan Hydrochloride
CAS No.: 138470-70-9
Chemical Name: Mozavaptan Hydrochloride
Synonyms: Mozavaptan HCl;OPC 31260 hydrochloride;Mozavaptan Hydrochloride;MOROBKPIULFQDC-UHFFFAOYSA-N;OPC 31260 hydrochloride >=98% (HPLC);5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine hydrochloride;N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide hydrochloride;N-[4-[[5-(Dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methylbenzamide hydrochloride;Benzamide,N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-,hydrochloride (1:1)
CBNumber: CB11508553
Molecular Formula: C27H29N3O2.ClH
Formula Weight: 464.006
MOL File: 138470-70-9.mol

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Mozavaptan Hydrochloride Property

storage temp.: 2-8°C
solubility: DMSO: ≥15mg/mL
form: powder
color: white to tan

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O1266
Product name: OPC 31260 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $95.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: O1266
Product name: OPC 31260 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $388
Updated: 2024/03/01

Cayman Chemical

Product number: 16664
Product name: Mozavaptan (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 16664
Product name: Mozavaptan (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $58
Updated: 2024/03/01

Cayman Chemical

Product number: 16664
Product name: Mozavaptan (hydrochloride)
Purity: ≥98%
Packaging: 50mg
Price: $126
Updated: 2024/03/01

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Mozavaptan Hydrochloride Chemical Properties,Usage,Production

Uses

Mozavaptan is a benzazepine derivative that antagonizes the binding of arginine vasopressin (AVP) to vasopressin receptors located in the liver (V1; IC50 = 1.2 μM) and kidney (V2; IC50 = 14 nM). At 10-100 μg/kg, mozavaptan can inhibit the antidiuretic action of AVP, promoting aquaresis when administered intravenously to rats. The therapeutic potential of mozavaptan in ectopic antidiuretic hormone syndrome, heart failure, and other complications related to hyponatremia has been studied.

Definition

ChEBI: Mozavaptane hydrochloride is a member of benzamides.

Biochem/physiol Actions

OPC 31260 is a vasopressin V2 selective antagonist. Arginine vasopressin (AVP) plays an important part in circulatory and water homeostasis. The V2 receptor subtype is important in water retention, cardiac remodeling in congestive heart failure (CHF), and renal hemodynamic alterations, and is considered a target for polysystic kidney disease. OPC-31260 has been shown to inhibit the development of polycystic kidney disease in several animal models.

Mozavaptan Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Mozavaptan Hydrochloride Suppliers

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138470-70-9, Mozavaptan Hydrochloride Related Search:

Trimethylamine hydrochloride Betaine hydrochloride Pyridine hydrochloride Dimethylamine hydrochloride Methylamine hydrochloride Cysteamine hydrochloride Mozavaptan Hydrochloride Mozavaptan

Mozavaptan Hydrochloride

N-[4-[[5-(Dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methylbenzamide hydrochloride

5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine hydrochloride

N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide hydrochloride

OPC 31260 hydrochloride

Mozavaptan HCl

MOROBKPIULFQDC-UHFFFAOYSA-N

OPC 31260 hydrochloride >=98% (HPLC)

Benzamide,N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-,hydrochloride (1:1)

138470-70-9

C27H29N3O2HCl