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POLY(N-ISOPROPYL ACRYLAMIDE)

Product Name
POLY(N-ISOPROPYL ACRYLAMIDE)
CAS No.
25189-55-3
Chemical Name
POLY(N-ISOPROPYL ACRYLAMIDE)
Synonyms
PNIPAM;CHEBI:53234;nipam polymer;PNIPAm MW:500;PNIPAm MW:4000;PNIPAM MW:8500;PNIPAm MW:2000;PNIPAAm56KDa-COOH;POLY(N-ISOPROPYL ACRYLAMIDE);N-ISO-PROPYLACRYLAMIDE POLYMER
CBNumber
CB1188228
Molecular Formula
C6H11NO
Formula Weight
113.15764
MOL File
25189-55-3.mol
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POLY(N-ISOPROPYL ACRYLAMIDE) Property

Melting point:
96 °C(lit.)
Density 
1.386 g/cm3
Tg
130
storage temp. 
-20°C
form 
powder
color 
white to off-white
InChI
InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChIKey
QNILTEGFHQSKFF-UHFFFAOYSA-N
SMILES
C(NC(C)C)(=O)C=C
EPA Substance Registry System
2-Propenamide, N-(1-methylethyl)-, homopolymer (25189-55-3)
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Safety

WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900188
Product name
Poly(<I>N</I>-isopropyl acrylamide)
Purity
NHS ester end functionalized, average M<SUB>n</SUB> 5,000
Packaging
1 g
Price
$381
Updated
2025/07/31
Sigma-Aldrich
Product number
806366
Product name
Poly(<I>N</I>-isopropyl acrylamide)
Purity
carboxylic acid, thiol
Packaging
1 g
Price
$518.7
Updated
2025/07/31
Sigma-Aldrich
Product number
535311
Product name
Poly(N-isopropyl acrylamide)
Purity
Mn ~40,000
Packaging
10g
Price
$847
Updated
2025/07/31
Sigma-Aldrich
Product number
900188
Product name
Poly(N-isopropyl acrylamide)
Purity
NHS ester end functionalized, average Mn 5,000
Packaging
1g
Price
$368
Updated
2024/03/01
Sigma-Aldrich
Product number
901422
Product name
Poly(N-isopropylacrylamide)
Purity
average Mn 85,000
Packaging
10G
Price
$352
Updated
2023/06/20
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POLY(N-ISOPROPYL ACRYLAMIDE) Chemical Properties,Usage,Production

Chemical Properties

mp 96°C phase transitions at 32°C to insoluble phase

Uses

PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Uses

Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Definition

ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide.

General Description

Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications.

Solubility in organics

Acetone, THF, water (cold)

POLY(N-ISOPROPYL ACRYLAMIDE) Preparation Products And Raw materials

Raw materials

Preparation Products

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POLY(N-ISOPROPYL ACRYLAMIDE) Suppliers

Alfa Chemistry
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View Lastest Price from POLY(N-ISOPROPYL ACRYLAMIDE) manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
poly(n-isopropyl acrylamide) 25189-55-3
Price
US $5.90-3.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-13

25189-55-3, POLY(N-ISOPROPYL ACRYLAMIDE)Related Search:


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  • POLY(N-ISOPROPYL ACRYLAMIDE) ISO 9001:2015 REACH
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  • CHEBI:53234
  • PNIPAm MW:4000
  • PNIPAM MW:8500
  • PNIPAm MW:2000
  • PNIPAAm56KDa-COOH
  • PNIPAm MW:500
  • 25189-55-3
  • CH3C6H11NOnCH3
  • Acrylamides
  • Acrylics
  • Biomaterials
  • Hydrogels and Crosslinked Polymers
  • Hydrophilic Polymers
  • Materials Science
  • Polymer Science
  • Polymers