ChemicalBook > CAS DataBase List > SB 204741

SB 204741

Product Name
SB 204741
CAS No.
152239-46-8
Chemical Name
SB 204741
Synonyms
SB 204741;1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea;3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA;N-(1-METHYL-1H-5-INDOLYL)-N'-(3-METHYL-5-ISOTHIAZOLYL)UREA;1-(1-Methyl-1H-indol-5-yl)-3-(3-Methylisothiazol-5-yl)urea;N-(1-METHYL-1H-INDOLYL-5-YL)-N''-(3-METHYL-5-ISOTHIAZOLYL)UREA;Urea, N-(1-methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)-;human,inhibit,SB204741,5-HT Receptor,Inhibitor,remodeling,Serotonin Receptor,selective,SB 204741,isoproterenol-induced,affinity,SB-204741,5-hydroxytryptamine Receptor,myocardial
CBNumber
CB1207574
Molecular Formula
C14H14N4OS
Formula Weight
286.35
MOL File
152239-46-8.mol
More
Less

SB 204741 Property

Melting point:
>195°C (dec.)
storage temp. 
2-8°C
solubility 
DMSO: ~18 mg/mL, soluble
form 
solid
color 
orange
Stability:
Hygroscopic
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S0693
Product name
SB 204741
Purity
>98% (HPLC)
Packaging
10mg
Price
$214
Updated
2024/03/01
Sigma-Aldrich
Product number
S0693
Product name
SB 204741
Purity
>98% (HPLC)
Packaging
50mg
Price
$858
Updated
2024/03/01
Tocris
Product number
1372
Product name
SB 204741
Purity
≥99%(HPLC)
Packaging
10
Price
$162
Updated
2021/12/16
Tocris
Product number
1372
Product name
SB 204741
Purity
≥99%(HPLC)
Packaging
50
Price
$682
Updated
2021/12/16
TRC
Product number
S155025
Product name
SB 204741
Packaging
100mg
Price
$120
Updated
2021/12/16
More
Less

SB 204741 Chemical Properties,Usage,Production

Uses

SB 204741 is a potent, selective SR-2B antagonist.

Definition

ChEBI: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea is a member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. It has a role as a receptor modulator and a serotonergic antagonist. It is a member of ureas, a member of indoles and a member of 1,2-thiazoles.

Biological Activity

Potent and selective 5-HT 2B receptor antagonist (pA 2 = 7.95). Displays ≥ 135-fold selectivity over 5-HT 2C (pK i = 5.82), 5-HT 2A (pK i < 5.2), 5-HT 1A , 1D , 1E , 5-HT 3 and 5-HT 4 receptors.

storage

Room temperature

SB 204741 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

SB 204741 Suppliers

China 51 Germany 1 Switzerland 1 United Kingdom 4 United States 9 USA 1 Global 67
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4397
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
4966
Advantage
55
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2988
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30238
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Hengyang Jiaxuan Biotechnology Co. LTD
Tel
18684598761
Fax
QQ：675042965
Email
675042965@qq.com
Country
China
ProdList
308
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Nanjing zehe Pharmaceutical Technology Co., Ltd
Tel
17768115366
Email
henry124604479@163.com
Country
China
ProdList
255
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，
Tel
028-83243028 19136088901
Email
sinostandards@163.com
Country
China
ProdList
4985
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
7977
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44458
Advantage
58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
4415
Advantage
58
Nantong Hi-Future Biotechnology Co., Ltd
Tel
18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
3033
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
Tel
+86-027-59232304 15387063101
Email
2881924050@qq.com
Country
China
ProdList
9956
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
WEITIXIHAUGONG
Tel
0371-53370800 18037197114
Email
2853031799@qq.com
Country
China
ProdList
9998
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
Shanghai jerryxing Biomedical Technology Co., Ltd
Tel
17721492509
Email
643638326@qq.com
Country
China
ProdList
5345
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
29971
Advantage
58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd
Tel
17316404525
Email
209533805@qq.com
Country
China
ProdList
9765
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
Tel
13915962545
Email
2881759498@qq.com
Country
China
ProdList
3660
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58
Nantong HI-FUTURE Biology Co., Ltd.
Tel
+undefined18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
3135
Advantage
58
Shanghai yiji industries Co., Ltd.
Tel
--
Fax
--
Email
yiji01@foxmail.com
Country
China
ProdList
6289
Advantage
50
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Beijing Dongge Boye Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1861586486@qq.com
Country
CHINA
ProdList
6648
Advantage
58
Qingdao Jieshikang Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
jskangchina@163.com
Country
CHINA
ProdList
4012
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6158
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
--
Fax
--
Email
kexianxun@gmail.com
Country
China
ProdList
1037
Advantage
50
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Shanghai Silk Dragon Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
3988
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Beijing Baiao Innovation Technology Co., Ltd.
Tel
--
Fax
--
Email
3007606172@qq.com
Country
CHINA
ProdList
6002
Advantage
58
Shanghai Yuda Industrial Co., Ltd.
Tel
--
Fax
--
Email
lucy@runwelltac.com
Country
CHINA
ProdList
6105
Advantage
58
Beijing Taize Jiaye Technology Development Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6050
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67
More
Less

View Lastest Price from SB 204741 manufacturers

Career Henan Chemica Co
Product
SB 204741 152239-46-8
Price
US $1.00/KG
Min. Order
1KG
Purity
MIn98%HPLC/LC
Supply Ability
100KGS
Release date
2020-10-29

152239-46-8, SB 204741Related Search:

Sb-742457 SBI-0206965 SB9200 GSK-CXCR2 SBI-993 SB-649868 SB1317 SB 203580 SB1317 5-AMINO-3-METHYLISOTHIAZOLE HYDROCHLORIDE SB 204741 3-METHYLISOTHIAZOLE 5-AMINO-1-N-METHYLINDOLE

  • SB 204741
  • N-(1-METHYL-1H-5-INDOLYL)-N'-(3-METHYL-5-ISOTHIAZOLYL)UREA
  • N-(1-METHYL-1H-INDOLYL-5-YL)-N''-(3-METHYL-5-ISOTHIAZOLYL)UREA
  • 1-(1-Methyl-1H-indol-5-yl)-3-(3-Methylisothiazol-5-yl)urea
  • 3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA
  • 1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea
  • Urea, N-(1-methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)-
  • human,inhibit,SB204741,5-HT Receptor,Inhibitor,remodeling,Serotonin Receptor,selective,SB 204741,isoproterenol-induced,affinity,SB-204741,5-hydroxytryptamine Receptor,myocardial
  • 152239-46-8
  • API