XPhos Pd G1

Reaction

Product Name: XPhos Pd G1
CAS No.: 1028206-56-5
Chemical Name: XPhos Pd G1
Synonyms: XPhos Pd;XPhos Pd G1;XPhos precatalyst;XPhos Palladacycle;XPhos Palladacycle Gen. 1;[2-(2-Aminoethyl)phenyl](chloro)palladium-dicyclohexyl(2',4'...;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) ;[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1);Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II);Chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1’-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
CBNumber: CB12129212
Molecular Formula: C41H59ClNPPd
Formula Weight: 738.77
MOL File: 1028206-56-5.mol

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XPhos Pd G1 Property

Melting point:: 205-210°C
form: Powder
color: white
CAS DataBase Reference: 1028206-56-5

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-52/53
Safety Statements: 26-61
WGK Germany: 3
HS Code: 2843909000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 704954
Product name: Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
Packaging: 1g
Price: $219
Updated: 2024/03/01

Sigma-Aldrich

Product number: 704954
Product name: Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
Packaging: 25g
Price: $1556
Updated: 2024/03/01

Strem Chemicals

Product number: 46-0268
Product name: Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]
Packaging: 1g
Price: $168
Updated: 2021/12/16

Strem Chemicals

Product number: 46-0268
Product name: Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]
Packaging: 250mg
Price: $56
Updated: 2021/12/16

Sigma-Aldrich

Product number: 704954
Product name: Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
Packaging: 250mg
Price: $46.26
Updated: 2024/03/01

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XPhos Pd G1 Chemical Properties,Usage,Production

Reaction

Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
Catalyst for rapid C-N bond-forming process at low catalyst loading.
Catalyst for C-N cross-coupling reactions, at or below room temperature.
Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates

Uses

XPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer.

Uses

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Catalyst used for:

Amination / cyclization reactions
C-N bond-forming reactions via packed-bed microreactors
Boration of aryl chlorides
Arylation of oxazole
Cross-coupling reactions

Preparation

XPhos Pd G1 is an insoluble solid that can be prepared by cross-coupling reactions of imidazole derivatives with dioxane.

General Description

Material may contain up to 5% pentane

Physiological effects

XPhos Pd G1 has been shown to have anti-infectious properties against bacteria and viruses including influenza A, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and hepatitis B. It also has metabolic effects on the body by reducing levels of pyridine compounds and increasing pyrazolyl concentrations in the blood stream.

XPhos Pd G1 Preparation Products And Raw materials

Raw materials

Preparation Products

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XPhos Pd G1 Suppliers

China 100 United Kingdom 1 United States 6 Global 107

CMS Chemicals Limited

Tel: --
Fax: --
Email: cms.marketing@cms-chemicals.com
Country: United Kingdom
ProdList: 3708
Advantage: 60

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View Lastest Price from XPhos Pd G1 manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: XPhos Pd G1 1028206-56-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-04-21

Wuhan LPBchem Technology Co.,Ltd

Product: Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct /XPhos Pd G1 1028206-56-5
Price: US $10.00-10.00/g
Min. Order: 1g
Purity: 0.98
Supply Ability: 50kg
Release date: 2020-11-25

Career Henan Chemical Co

Product: Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) 1028206-56-5
Price: US $1.00/g
Min. Order: 1g
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-07

1028206-56-5, XPhos Pd G1Related Search:

Chloro(2-dicyclohexylphosphino-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98% [BrettPhos Palladacycle] XPhos Pd G3 SPhos Palladacycle Gen. 4 XPhos Pd G4 Xantphos Pd G3 BrettPhos Pd G3 XPhos Pd G2 RuPhos Pd G1 Methyl t--Butyl Ether Adduct SPhos Pd G2 BrettPhosPalladacycle Palladacycle Gen. 3 t-BuXphos Palladacycle Gen. 4 RuPhos Palladacycle Gen. 4 t-BuBrettPhos Palladacycle Gen. 3 SPhos Pd G3 SPhos Pd G1, Methyl t-Butyl Ether Adduct RuPhos Pd G2 tBuXPhos Pd G1

XPhos Palladacycle

XPhos precatalyst

[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1)

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II)

XPhos Pd G1

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct

XPhos Pd

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]

Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle]

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl]palladiuM(II)Methyl-t-butyletheradduct,Min.98%

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98%

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl] palladiuM(II) Methyl-t-butylether adduct,98% XPhos Palladacycle

Palladium, [2-[2-(amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-, (SP-4-4)-

(SP-4-4)-[2-[2-(Amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]palladium

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl] palladiuM(II) Methyl-t-butylether adduct [XPhos Palladacycle]

Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-, (SP-4-4)-

XPhos Palladacycle Gen. 1

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct / XPhos Pd G1

[2-(2-Aminoethyl)phenyl](chloro)palladium-dicyclohexyl(2',4'...

XPhos Pd G1 / Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct

1028206-56-5 Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-bip

(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium

Chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1’-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)

Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct

(SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-

1028206-56-5

C41H59ClNPPd

Buchwald Ligands&Precatalysts

Buchwald Precatalysts Series

Pd