Methyl(p-formylphenyl)acetate
- Product Name
- Methyl(p-formylphenyl)acetate
- CAS No.
- 96524-70-8
- Chemical Name
- Methyl(p-formylphenyl)acetate
- Synonyms
- Methyl 2-(4-formylphenyl);Methyl(p-formylphenyl)acetate;Methyl (4-formylphenyl)acetate;Methyl 2-(4-formylphenyl)acetate;Methyl 2-(4-formylphenyl)acetate 98%;4-Formylbenzeneacetic acid methyl ester;(4-Formylphenyl)acetic acid methyl ester;Benzeneacetic acid, 4-formyl-, methyl ester;tert-butyl4-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]piperazine-6-carboxylate
- CBNumber
- CB12484540
- Molecular Formula
- C10H10O3
- Formula Weight
- 178.18
- MOL File
- 96524-70-8.mol
Methyl(p-formylphenyl)acetate Property
- Boiling point:
- 285℃
- Density
- 1.157
- Flash point:
- 124℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- Off-white to yellow Solid
- InChI
- InChI=1S/C10H10O3/c1-13-10(12)6-8-2-4-9(7-11)5-3-8/h2-5,7H,6H2,1H3
- InChIKey
- YPJYQGMVBYQTTA-UHFFFAOYSA-N
- SMILES
- C1(CC(OC)=O)=CC=C(C=O)C=C1
Safety
- HS Code
- 2918290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M219563
- Product name
- Methyl2-(4-formylphenyl)acetate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-W019639
- Product name
- Benzeneaceticacid,4-formyl-,methylester
- Purity
- ≥98.0%
- Packaging
- 1g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- OR313093
- Product name
- Methyl2-(4-formylphenyl)acetate
- Purity
- 98%
- Packaging
- 1g
- Price
- $218
- Updated
- 2021/12/16
- Product number
- 2623-1-86
- Product name
- Methyl 2-(4-formylphenyl)acetate
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- CS-W019639
- Product name
- Benzeneaceticacid,4-formyl-,methylester
- Purity
- ≥98.0%
- Packaging
- 5g
- Price
- $285
- Updated
- 2021/12/16
Methyl(p-formylphenyl)acetate Chemical Properties,Usage,Production
Synthesis
155380-11-3
96524-70-8
General procedure for the synthesis of methyl 4-formylphenylacetate from methyl 2-(4-(hydroxymethyl)phenyl)acetate: a solution was formed by dissolving Dess-Martin Periodinane (1.5 eq.) in dichloromethane (0.3 M) at room temperature and protected by nitrogen with stirring. Subsequently, a dichloromethane (0.2 M) solution of methyl 2-(4-(hydroxymethyl)phenyl)acetate was added to this solution. After the reaction was carried out for 4 hours, the reaction mixture was diluted with ether (0.1 M). Next, the reaction mixture was poured into a saturated sodium bicarbonate (0.5 M) solution containing sodium thiosulfate (10.5 equivalents) and stirred for 30 minutes. The organic and aqueous phases were separated and the organic phase was washed sequentially with saturated sodium bicarbonate solution (1 liter), water (1 liter) and brine (1 liter). The washed organic phase was dried with sodium sulfate, filtered and concentrated in vacuum to afford the target product methyl 4-formylphenylacetate in 94% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 10.00 (s, 1H), 7.86 (d, 2H), 7.46 (d, 2H), 3.72 (m, 5H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 10, p. 2647 - 2652
[2] Patent: US2004/254156, 2004, A1. Location in patent: Page 22
[3] Patent: WO2013/149997, 2013, A1. Location in patent: Page/Page column 47
[4] Patent: WO2014/86924, 2014, A1. Location in patent: Page/Page column 74; 75
[5] Patent: WO2007/106016, 2007, A1. Location in patent: Page/Page column 68
Methyl(p-formylphenyl)acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl(p-formylphenyl)acetate manufacturers
- Product
- Methyl(p-formylphenyl)acetate 96524-70-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- Methyl(p-formylphenyl)acetate 96524-70-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Methyl(p-formylphenyl)acetate 96524-70-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10