Nodinitib-1

Product Name: Nodinitib-1
CAS No.: 799264-47-4
Chemical Name: Nodinitib-1
Synonyms: ML 130;Nodinitib-1;Noditinib-1;CID-1088438;Noditiniβ-1;ML-130;ML 130;130 (Nodinitib-1);ML130;CID-1088438;ML130 (Nodinitib-1);Nodinitib-1 USP/EP/BP
CBNumber: CB12591864
Molecular Formula: C14H13N3O2S
Formula Weight: 287.34
MOL File: 799264-47-4.mol

More

Less

Nodinitib-1 Property

Melting point:: 191-192 °C (decomp)
Boiling point:: 532.5±43.0 °C(Predicted)
Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO: >10mg/mL
form: powder
pka: 2.55±0.10(Predicted)
color: white to beige

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0379
Product name: Nodinitib-1
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $79.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0379
Product name: Nodinitib-1
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $523
Updated: 2024/03/01

Cayman Chemical

Product number: 11040
Product name: Nodinitib-1
Purity: ≥95%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 11040
Product name: Nodinitib-1
Purity: ≥95%
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 11040
Product name: Nodinitib-1
Purity: ≥95%
Packaging: 25mg
Price: $193
Updated: 2024/03/01

More

Less

Nodinitib-1 Chemical Properties,Usage,Production

Uses

Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.

Definition

ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.

Biological Activity

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.

Nodinitib-1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Nodinitib-1 Suppliers

Canada 1 China 66 India 2 United Kingdom 1 United States 16 Global 86

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Abcam

Tel: --
Fax: --
Email: us.orders@abcam.com
Country: United States
ProdList: 6001
Advantage: 50

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Creative Enzymes

Tel: --
Fax: --
Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

More

Less

View Lastest Price from Nodinitib-1 manufacturers

Career Henan Chemical Co

Product: Nodinitib-1 799264-47-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

799264-47-4, Nodinitib-1Related Search:

M348 ML-228 VU0456810 9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- ML-327 AG 1478 HYDROCHLORIDE Paclitaxel Trametinib Veliparib Olaparib ML402 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide ML-098 [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone 9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)- ML 339 ML 141 ML198

Nodinitib-1

1H-BenziMidazol-2-aMine, 1-[(4-Methylphenyl)sulfonyl]-

ML 130

1-[(4-Methylphenyl)sulfonyl]-1H-benziMidazol-2-aMine

Noditinib-1

ML130 (Nodinitib-1)

CID-1088438

1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-ylamine

ML130;CID-1088438

ML-130;ML 130

130 (Nodinitib-1)

Nodinitib-1 USP/EP/BP

Noditiniβ-1

1-Tosyl-1H-benzo[d]imidazol-2-amine

Nodinitib1,CID1088438,Inhibitor,NOD-like Receptor (NLR),Nodinitib 1,ML-130,ML 130,Nodinitib-1,CID 1088438,inhibit

1-(4-methylphenyl)sulfonylbenzimidazol-2-amine

ML130, NOD1 inhibitor

Nodinitib-1, 10 mM in DMSO

799264-47-4

API

NF-kB

Amines

Aromatics

Heterocycles

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds