ChemicalBook > CAS DataBase List > Ethoxycarbonyl Isothiocyanate

Ethoxycarbonyl Isothiocyanate

Product Name
Ethoxycarbonyl Isothiocyanate
CAS No.
16182-04-0
Chemical Name
Ethoxycarbonyl Isothiocyanate
Synonyms
O-ethyl carbonisothiocyanatidate;ethyl N-carbothioylcarbamate;ETHYL ISOTHIOCYANATOFORMATE;Ethyl carbonisothiocyanatidate;NSC 158480;CARBETHOXYISOTHIOCYANATE;Ethoxycarbonyl Mustard Oil;ETHOXYCARBONYL ISOTHIOCYANATE;ETHYL ISOTHIOCYANATOFORMATE,98%;Ethyl isothiocyanatidocarbonate
CBNumber
CB1265381
Molecular Formula
C4H5NO2S
Formula Weight
131.15
MOL File
16182-04-0.mol
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Ethoxycarbonyl Isothiocyanate Property

Boiling point:
56 °C18 mm Hg(lit.)
Density 
1.112 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.500(lit.)
Flash point:
123 °F
storage temp. 
2-8°C
solubility 
Soluble in chloroform and ether.
form 
Oil
Specific Gravity
1.112
color 
Light Yellow
Sensitive 
Moisture Sensitive/Lachrymatory
BRN 
606091
InChIKey
BDTDECDAHYOJRO-UHFFFAOYSA-N
CAS DataBase Reference
16182-04-0(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
23-36/37/38-42
Safety Statements 
23-26-36/37/39-45
RIDADR 
UN 2929 6.1/PG 2
WGK Germany 
3
9-13-19-21
HazardClass 
3
PackingGroup 
III
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H331Toxic if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
196126
Product name
Ethoxycarbonyl isothiocyanate
Purity
98%
Packaging
5g
Price
$89.6
Updated
2024/03/01
Sigma-Aldrich
Product number
196126
Product name
Ethoxycarbonyl isothiocyanate
Purity
98%
Packaging
25g
Price
$260
Updated
2024/03/01
TCI Chemical
Product number
E0440
Product name
Ethoxycarbonyl Isothiocyanate
Purity
>95.0%(GC)
Packaging
5g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
E0440
Product name
Ethoxycarbonyl Isothiocyanate
Purity
>95.0%(GC)
Packaging
25g
Price
$88
Updated
2024/03/01
Alfa Aesar
Product number
L00911
Product name
Ethoxycarbonyl isothiocyanate, 97%
Packaging
5g
Price
$63.65
Updated
2024/03/01
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Ethoxycarbonyl Isothiocyanate Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Uses

Versatile reagent for organic synthesis.
Ethoxycarbonyl isothiocyanate is used as a building block in the synthesis of various heterocycles. It is also used for the synthesis of 1,2,4-oxadiazolidine-3,5-dione. It is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Uses

Ethoxycarbonyl isothiocyanate has been used in the synthesis of:

  • pyrazolo[1,5-a][1,3,5]triazine derivatives, potential inhibitors of protein kinase CK2
  • fused thiophene derivatives, having antibacterial and antifungal activities
  • 4-thiouracil derivatives
  • thiocarbamides from stannylarenes
  • 1,3,5-triazin-2-one-4-thiones from 2-amino-2-oxazolines
  • N-acylthioureas from aminodeoxy sugars

Application

Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives.
Ethoxycarbonyl isothiocyanate has been used in the synthesis of:
pyrazolo[1,5-a][1,3,5]triazine derivatives, potential inhibitors of protein kinase CK2
fused thiophene derivatives, having antibacterial and antifungal activities
4-thiouracil derivatives
thiocarbamides from stannylarenes
1,3,5-triazin-2-one-4-thiones from 2-amino-2-oxazolines
N-acylthioureas from aminodeoxy sugars

Synthesis Reference(s)

Using Schiff base as a phase transfer catalyst, ethoxycarbonyl isothiocyanate was synthesized by reacting ethyl chloroformate with sodium thiocyanate. www.semanticscholar.org

General Description

Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives.

Hazard

Lachrymator.

Ethoxycarbonyl Isothiocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethoxycarbonyl Isothiocyanate Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Noven Lifesciences Private Limited
Tel
--
Fax
--
Country
India
ProdList
21
Advantage
58
Noble Molecular Research
Tel
--
Fax
--
Country
India
ProdList
53
Advantage
58
V Indaf Overseas Pvt., Ltd.
Tel
--
Fax
--
Email
info@vindaf.com
Country
India
ProdList
117
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
Sai Sree Chemicals
Tel
--
Fax
--
Email
saisreechemicals205@gmail.com
Country
India
ProdList
89
Advantage
58
Quiver Technologies
Tel
--
Fax
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Country
India
ProdList
169
Advantage
58
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View Lastest Price from Ethoxycarbonyl Isothiocyanate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethoxycarbonyl Isothiocyanate 16182-04-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-03
Hebei Mojin Biotechnology Co., Ltd
Product
Ethoxycarbonyl Isothiocyanate 16182-04-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
ETHOXYCARBONYL ISOTHIOCYANATE 16182-04-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

16182-04-0, Ethoxycarbonyl IsothiocyanateRelated Search:


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