Uses
ChemicalBook > CAS DataBase List > p-Trifluoromethoxy phenol

p-Trifluoromethoxy phenol

Uses
Product Name
p-Trifluoromethoxy phenol
CAS No.
828-27-3
Chemical Name
p-Trifluoromethoxy phenol
Synonyms
4-(TRIFLUOROMETHOXY)PHENOL;TFMOPO;uoromethoxy)phenoL;TIMTEC-BB SBB006554;p-Trifluoromethoxy p;4-trifluoroMethoxylphenol;p-(Triflourmethoxy)phenol;P-(TRIFLUOROMETHOXY)PHENOL;PHENOL,4-(TRIFLUOROMETHOXY);4-(TrifluorMethoxy)benzolol
CBNumber
CB1268120
Molecular Formula
C7H5F3O2
Formula Weight
178.11
MOL File
828-27-3.mol
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p-Trifluoromethoxy phenol Property

Melting point:
17-18°C
Boiling point:
92 °C25 mm Hg(lit.)
Density 
1.375 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.447(lit.)
Flash point:
187 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform, Methanol
form 
Liquid
pka
9.30±0.13(Predicted)
Specific Gravity
1.375
color 
Clear brown
BRN 
1945934
InChIKey
NWVVVBRKAWDGAB-UHFFFAOYSA-N
CAS DataBase Reference
828-27-3(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-(trifluoromethoxy)-(828-27-3)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-27-36/37/39
RIDADR 
2927
WGK Germany 
2
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29095090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
339865
Product name
4-(Trifluoromethoxy)phenol
Purity
98%
Packaging
1g
Price
$24
Updated
2023/01/07
Sigma-Aldrich
Product number
339865
Product name
4-(Trifluoromethoxy)phenol
Purity
98%
Packaging
5g
Price
$43
Updated
2023/01/07
TCI Chemical
Product number
T1341
Product name
4-(Trifluoromethoxy)phenol
Purity
>95.0%(GC)
Packaging
5g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
T1341
Product name
4-(Trifluoromethoxy)phenol
Purity
>95.0%(GC)
Packaging
25g
Price
$26
Updated
2024/03/01
Alfa Aesar
Product number
A12695
Product name
4-(Trifluoromethoxy)phenol, 98%
Packaging
1g
Price
$34.1
Updated
2021/12/16
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p-Trifluoromethoxy phenol Chemical Properties,Usage,Production

Uses

4-(Trifluoromethoxy)phenol is used as a reactant in the preparation of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors.

Chemical Properties

clear brown liquid

Uses

4-(Trifluoromethoxy)phenol is used as a reactant in the preparation of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors.

Uses

4-(Trifluoromethoxy)phenol was employed in the catalytic enantioselective synthesis of esters.

Uses

Intermediates of Liquid Crystals

Synthesis Reference(s)

Journal of Medicinal Chemistry, 25, p. 1097, 1982 DOI: 10.1021/jm00351a018

p-Trifluoromethoxy phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from p-Trifluoromethoxy phenol manufacturers

Henan Fengda Chemical Co., Ltd
Product
p-Trifluoromethoxy phenol 828-27-3
Price
US $6.00-0.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-18
Shaanxi Dideu Medichem Co. Ltd
Product
p-Trifluoromethoxy phenol 828-27-3
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%
Supply Ability
2000tons
Release date
2020-01-16
Hebei Yanxi Chemical Co., Ltd.
Product
p-Trifluoromethoxy phenol 828-27-3
Price
US $20.00-8.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
30 tons per month
Release date
2023-10-08

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