AG 825

Product Name: AG 825
CAS No.: 149092-50-2
Chemical Name: AG 825
Synonyms: AG 825;Zinc02572484;TYRPHOSTIN C15;AG 825 USP/EP/BP;TYRPHOSTIN AG 825;AG 825, ErbB2 inhibitor;AG 825 (Tyrphostin AG 825);AG 825 - CAS 149092-50-2 - Calbiochem;4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE;5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
CBNumber: CB1283828
Molecular Formula: C19H15N3O3S2
Formula Weight: 397.47
MOL File: 149092-50-2.mol

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AG 825 Property

storage temp.: −20°C
solubility: DMSO: soluble
form: Yellow solid
color: Light yellow to yellow
Sensitive: Light Sensitive

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T5443
Product name: Tyrphostin AG 825
Purity: ≥92.5%
Packaging: 2mg
Price: $52.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 121765
Product name: AG 825
Packaging: 2mg
Price: $172
Updated: 2024/03/01

Alfa Aesar

Product number: J65227
Product name: Tyrphostin C15
Packaging: 10mg
Price: $233.65
Updated: 2024/03/01

Cayman Chemical

Product number: 10010243
Product name: AG 825
Purity: ≥98%
Packaging: 1mg
Price: $28
Updated: 2024/03/01

Cayman Chemical

Product number: 10010243
Product name: AG 825
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

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AG 825 Chemical Properties,Usage,Production

Uses

A selective ErbB2 inhibitor

Uses

AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.

Definition

ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

Biological Activity

Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

storage

Store at +4°C

AG 825 Preparation Products And Raw materials

Raw materials

Preparation Products

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AG 825 Suppliers

China 60 Germany 4 India 1 Switzerland 2 United Kingdom 5 United States 23 USA 1 Global 96

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Suzhou Chireach Biomedical Technology Co., Ltd.

Tel: 0512-65856968
Fax: 0512-65647218
Email: sales@chireach.com
Country: China
ProdList: 59
Advantage: 70

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Synchem OHG

Tel: +49 5662 408730
Fax: +49 5662 4087320
Email: info@synchem.de
Country: Germany
ProdList: 4705
Advantage: 70

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7298
Advantage: 58

149092-50-2, AG 825Related Search:

AG 1478 HYDROCHLORIDE DAPH AG 18 LAVENDUSTIN A METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH TYRPHOSTIN A25 Canertinib 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol AG 213 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE PD168393 TYRPHOSTIN A51 CIVENTICHEM CV-409 AG 825 AG 99 4-METHYL-2-[(METHYLTHIO)METHYL]PHENOL AKOS BBS-00008114

TYRPHOSTIN AG 825

TYRPHOSTIN C15

AG 825

5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE

5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE

4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE

3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- 2-Propenamide

Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide

AG 825 (Tyrphostin AG 825)

(E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE

AG 825 - CAS 149092-50-2 - Calbiochem

Zinc02572484

2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-

AG 825 USP/EP/BP

3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide

AG 825, ErbB2 inhibitor

149092-50-2

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Kinase/Phosphatase Biology

Receptor Tyrosine Kinase Inhibitors

Epidermal Growth Factor Receptor (EGFR)

Protein Kinase