ChemicalBook > CAS DataBase List > FIBROBLAST GROWTH FACTOR, BASIC, HUMAN

FIBROBLAST GROWTH FACTOR, BASIC, HUMAN

Product Name
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN
CAS No.
106096-93-9
Chemical Name
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN
Synonyms
BFGF;DRK1;kcb-1;HBFGF;FGF-2;KCNB1;RHFGFB;RHBFGF;NBBFGF;fce26184
CBNumber
CB1291397
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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FIBROBLAST GROWTH FACTOR, BASIC, HUMAN Property

storage temp. 
-20°C
form 
lyophilized powder
color 
white to faint yellow cast
CAS DataBase Reference
106096-93-9
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
LK3641325
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP4039
Product name
Fgf-2 from rat
Purity
recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
Packaging
50μG
Price
$347
Updated
2024/03/01
Sigma-Aldrich
Product number
SRP4037
Product name
FGF-2 human
Purity
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
Packaging
50μg
Price
$339
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB4501621
Product name
Anti-KV2.1 antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μg
Price
$506
Updated
2024/03/01
Sigma-Aldrich
Product number
F5392
Product name
Fibroblast Growth Factor-Basic from bovine pituitary
Purity
FGF-Basic, suitable for cell culture
Packaging
1μg
Price
$332.4
Updated
2024/03/01
Sigma-Aldrich
Product number
F0291
Product name
hBFGF
Purity
FGF-Basic, recombinant, expressed in E. coli, suitable for cell culture
Packaging
25μg
Price
$308
Updated
2024/03/01
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FIBROBLAST GROWTH FACTOR, BASIC, HUMAN Chemical Properties,Usage,Production

Uses

Fibroblast growth factor-basic (FGF-Basic) is required for the maintenance of human embryonic stem cells in culture, and various other stem cell lines, such as mesenchymal stem (stroma) cells (MSC).

General Description

Fibroblast growth factor-basic (FGF-Basic) is found in basement membranes and sub-endothelial extracellular matrix. FGF-Basic is induced early in the development of the embryo where it is necessary (but not sufficient) for pluripotency and self-renewal of embryonic stem cells (ESC) and lineage defined stem cells; wherein it functions to support proliferation and inhibit differentiation. Self-renewal of hESC depends upon activation of the Activin/Nodal/Smad2,3 branch and suppression of the BMP/GDF/Smad5 branch of the TGFβ-family cell signaling program. FGF-Basic is a competence factor for Nodal support of pluripotency. Activin-A is necessary and sufficient to maintain stemness. It induces the expression of both Nodal and FGF-Basic in human ES cells.

Biochem/physiol Actions

FGF2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) interacts with FGFR1 (fibroblast growth factor receptor 1), FGFR2 and FGFR3. It stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. FGF2 also determines the fate of neural precursor cells and promotes neuronal axon regeneration. It plays an important role in spinal cord injury repair. FGF2 is known to stimulate angiogenesis and is associated with cancer development. High levels of FGF2 are present in the kidney of children with HIV (human immunodeficiency virus)-renal diseases. The FGF2 mRNA is a target of miRNA miR-503.

FIBROBLAST GROWTH FACTOR, BASIC, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FIBROBLAST GROWTH FACTOR, BASIC, HUMAN manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN 106096-93-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-10-11

106096-93-9, FIBROBLAST GROWTH FACTOR, BASIC, HUMANRelated Search:

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  • FIBROBLAST GROWTH FACTOR, BASIC, RECOMBINANT
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  • FGF-2, BOVINE
  • FGF-2, HUMAN
  • FGF-2, HUMAN, RECOMBINANT
  • FGF-BASIC
  • FGF-BASIC (HUMAN)
  • FGF-BASIC PEPTIDE
  • FGF-B HUMAN
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  • BOVINE FIBROBLAST GROWTH FACTOR BASIC
  • BFGE HUMAN
  • BFGF
  • BFGF BOVINE
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  • BASIC FIBROBLAST GROWTH FACTOR (FGF 2) HUMAN
  • BASIC FGF
  • BASIC FGF, HUMAN
  • BASIC FIBROBLAST GROWTH FACTOR, HUMAN
  • Anti-KV2.1 antibody produced in rabbit
  • DRK1
  • KCNB1
  • Potassium channel Kv2.1
  • Potassium voltage-gated channel subfamily B member 1
  • ANTI-FGF2-T254 antibody produced in rabbit
  • Fgf-2 from rat
  • FGF-2, Basic, Human, Recombinant,
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