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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

Product Name
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
CAS No.
1201187-44-1
Chemical Name
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Synonyms
tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate;Upadacitinib Impurity 3;Upadacitinib Intermediate4;Upadacitinib intermediate2;Intermediate of Upadacitinib (ABT-494);2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate;N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...;tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate;2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
CBNumber
CB13102742
Molecular Formula
C18H20N4O4S
Formula Weight
388.44
MOL File
1201187-44-1.mol
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Property

Density 
1.35±0.1 g/cm3(Predicted)
pka
9.45±0.43(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B809575
Product name
tert-ButylN-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
Packaging
250mg
Price
$220
Updated
2021/12/16
Chemenu
Product number
CM119289
Product name
2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity
95%+
Packaging
1g
Price
$310
Updated
2021/12/16
Chemenu
Product number
CM119289
Product name
2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity
95%+
Packaging
5g
Price
$858
Updated
2021/12/16
Crysdot
Product number
CD11333434
Product name
tert-Butyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
Purity
97%
Packaging
1g
Price
$1085
Updated
2021/12/16
Chemenu
Product number
CM119289
Product name
2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity
95%+
Packaging
10g
Price
$1788
Updated
2021/12/16
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemical Properties,Usage,Production

Uses

tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.

Uses

Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Suppliers

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View Lastest Price from tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate manufacturers

Henan Fengda Chemical Co., Ltd
Product
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate 1201187-44-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-10
Hangzhou ICH Biofarm Co., Ltd
Product
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate 1201187-44-1
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-09
Hangzhou ICH Biofarm Co., Ltd
Product
Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester 1201187-44-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2023-06-30

1201187-44-1, tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamateRelated Search:

tert-Butyl (4-methylpiperidin-4-yl)carbamate tert-Butyl 3-oxoazetidine-1-carboxylate tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Upadacitinib tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate tert-Butyl 3-phenyl-L-alaninate hydrochloride tert-Butyl 3-allyl-4-oxopyrrolidine-1-carboxylate (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester (3R,4S)-1-[(benzyloxy)carbonyl]-4-ethylpyrrolidine-3-carboxylic acid 5-[(4-methylphenyl)sulfonyl]-5H-Pyrrolo[2,3-b]pyrazin-2-amine 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate

  • tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
  • tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
  • Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester
  • tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
  • Intermediate of Upadacitinib (ABT-494)
  • 2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
  • Upadacitinib intermediate2
  • 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
  • N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...
  • Upadacitinib Impurity 3
  • Upadacitinib Intermediate4
  • N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester
  • 1201187-44-1