ChemicalBook > CAS DataBase List > tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

Product Name: tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
CAS No.: 1201187-44-1
Chemical Name: tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Synonyms: tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate;Upadacitinib Impurity 3;Upadacitinib Intermediate4;Upadacitinib intermediate2;Upadacitinib Intermediates;Intermediate of Upadacitinib (ABT-494);2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbama;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate;tert-butyl 5-tosyl-5H-pyrrolo[2,3-blpyrazin-2-ylcarbamate
CBNumber: CB13102742
Molecular Formula: C18H20N4O4S
Formula Weight: 388.44
MOL File: 1201187-44-1.mol

Less

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Property

Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Store at Room Tem.
pka: 9.45±0.43(Predicted)
InChI: InChI=1S/C18H20N4O4S/c1-12-5-7-13(8-6-12)27(24,25)22-10-9-14-16(22)19-11-15(20-14)21-17(23)26-18(2,3)4/h5-11H,1-4H3,(H,20,21,23)
InChIKey: NTMJGYRFMXFNIC-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NC1=CN=C2N(S(C3=CC=C(C)C=C3)(=O)=O)C=CC2=N1

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TRC

Product number: B809575
Product name: tert-ButylN-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
Packaging: 250mg
Price: $220
Updated: 2021/12/16

Chemenu

Product number: CM119289
Product name: 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity: 95%+
Packaging: 1g
Price: $310
Updated: 2021/12/16

Chemenu

Product number: CM119289
Product name: 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity: 95%+
Packaging: 5g
Price: $858
Updated: 2021/12/16

Crysdot

Product number: CD11333434
Product name: tert-Butyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
Purity: 97%
Packaging: 1g
Price: $1085
Updated: 2021/12/16

Chemenu

Product number: CM119289
Product name: 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Purity: 95%+
Packaging: 10g
Price: $1788
Updated: 2021/12/16

Less

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemical Properties,Usage,Production

Uses

tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.

Uses

Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Suppliers

China 245 India 6 United States 7 Global 258

Hangzhou Cheminspire Technology Co., Ltd.

Tel: 0571-89081561; 10006559855
Fax: 0571 89081561
Email: info@cheminspire.com
Country: China
ProdList: 412
Advantage: 58

Hangzhou Chemtrue Bio-Tech Co.,Ltd.

Tel: 0571-86828652 18857119830
Fax: 0571-83522824
Email: sales@chemtrue-bio.com
Country: China
ProdList: 252
Advantage: 58

Jiangsu Vcare PharmaTech Co., Ltd.

Tel: 025-58741518 13327700685
Fax: +86-25-58744115
Email: sales@vcarepharmatech.com
Country: China
ProdList: 308
Advantage: 61

Heading （Nanjing）Pharmtechnologies Co., Ltd.

Tel: 025-58467899-832 13382406280
Fax: 025-58467899
Email: liucheng@headingpharm.com
Country: China
ProdList: 45
Advantage: 58

Guangzhou Anyanren Pharmaceutical Technology Co., Ltd.

Tel: 18028661570
Email: 2412659056@qq.com
Country: China
ProdList: 291
Advantage: 58

Cangzhou Kangrui Medical Technology Co., LTD

Tel: 18632776803
Email: 355803330@qq.com
Country: China
ProdList: 630
Advantage: 58

Jinan Chenghui Shuangda biological Co., LTD

Tel: 0531-0531-58897003 15550412551
Fax: 0531-58897003
Email: market@jnchsd.com
Country: China
ProdList: 229
Advantage: 62

Chongqing Richem Biotechnology Co., Ltd.

Tel: 13983114937
Email: 382562851@qq.com
Country: China
ProdList: 78
Advantage: 58

Beijing Huikang Boyuan Chemical Tech Co., Ltd

Tel: 010-68862197 13810598707
Fax: 010-68882204
Email: sales@huikangchem.com
Country: China
ProdList: 109
Advantage: 61

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Sichuan Tongsheng Amino acids Co.,Ltd.

Tel: 0838-2274206 13908101207
Fax: +86-838-2274207
Email: sales@biots.cn
Country: China
ProdList: 279
Advantage: 66

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 13801208576
Fax: 010-64215766
Email: maggie@chinazhongshuo.com
Country: China
ProdList: 77
Advantage: 65

Changzhou Joyous Chemical Co., Ltd.

Tel: 0519-85607258 13912342323;
Fax: 0519-85607278
Email: sales@joyouschem.com
Country: China
ProdList: 294
Advantage: 60

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: 15928766785 15928766785
Fax: QQ961458712
Email: wupengcheng@astatech.cn
Country: China
ProdList: 1987
Advantage: 55

Suli Pharmaceutical Technology Co., Ltd.

Tel: 021-58086325-8060 13636568474
Fax: 021-51972827
Email: yingjie.zhang@suli.com
Country: China
ProdList: 100
Advantage: 58

Jinan XuanDe Chemical Co., Ltd.

Tel: 0531-88803958 18866891188
Fax: 0531-82777287
Email: 18853169188@163.com
Country: China
ProdList: 193
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Shandong Juntai Pharmaceutical Co., LTD.

Tel: 15853135817
Fax: 0531-66958526
Email: sales@h2opharm.com
Country: China
ProdList: 201
Advantage: 55

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 294
Advantage: 55

Sichuan Argalbio Technology Co,.Ltd

Tel: 028-028-60651388 13330964498
Email: slyu@hengkangtech.com
Country: China
ProdList: 378
Advantage: 58

Shanghai YuanQi Biotechnology Co., Ltd.

Tel: +86-2332782371 +86-18120098618
Email: sales@adobechem.com
Country: China
ProdList: 1250
Advantage: 50

Gansu HaoTian Chemical Technology Co., Ltd.

Tel: 0943-6900332 17789447501
Fax: 0931-8238232
Email: zhuanxiajiang@haotianpharm.com
Country: China
ProdList: 192
Advantage: 55

Nova(Shanghai) Pharmaceutical Co.,Ltd

Tel: 21-58226973 18917146209
Fax: +86-21-51685790
Email: Joseph@novapharmas.com
Country: China
ProdList: 476
Advantage: 55

ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD

Tel: 0571-87322520 18957127338
Fax: QQ:3007632051
Email: sales@zetchem.com
Country: China
ProdList: 467
Advantage: 55

Anqing CHICO Pharmaceutical Co., Ltd.

Tel: 13585175604 13057662806
Fax: +86-25-52261140
Email: sales@chicopharm.com
Country: China
ProdList: 500
Advantage: 65

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Suzhou PengXu PharmaTech Co., Ltd.

Tel: 15850786624
Email: sales@cqpharm.com
Country: China
ProdList: 88
Advantage: 58

Shanghai Rochi Pharmaceutical Co., Ltd.

Tel: 021-38751876 15000076078
Fax: 021-50275764
Email: Info@rochipharma.com
Country: China
ProdList: 611
Advantage: 55

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9279
Advantage: 55

Shandong Xuande Pharmaceutical Technology Co. LTD

Tel: 18866895588
Fax: 0531-82777287
Email: dingjiaying@shiningpharm.com
Country: China
ProdList: 163
Advantage: 55

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 2267
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Hubei widely chemical technology Co., Ltd.

Tel: 027-59402396 13419635609
Fax: 027-83989310
Email: 13419635609@163.com
Country: China
ProdList: 1991
Advantage: 55

Wuhan Wsem Biological Co., Ltd.

Tel: 027-83778876 13667159345
Fax: 027-83778876
Email: 13667159345@163.com
Country: China
ProdList: 1997
Advantage: 55

Adobe Chem Co., Ltd.

Tel: 2332782371
Fax: QQ: 2332782371
Email: adobechem@qq.com
Country: China
ProdList: 7980
Advantage: 58

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Chiral Quest (Suzhou) Co., Ltd.

Tel: 0512-62956066 18112603058
Email: kendoll@cqpharm.com
Country: China
ProdList: 96
Advantage: 58

CHENGHUI PHARMACEUTICAL GROUP LTD

Tel: 531-58897070 15254140813
Fax: 0531-58897046
Email: market@jnchsd.com
Country: China
ProdList: 235
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 1788
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Shanghai jing Hao pharmaceutical technology co., LTD

Tel: 021-68900963 15618693615
Fax: 021-68900963
Email: sales@jinghaopharma.com
Country: China
ProdList: 300
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10267
Advantage: 58

Suzhou Southeast Pharmaceutical Co., Ltd.

Tel: 18915562593 / 0512－62729923 13915545693
Fax: 0517-86993111
Email: info@szsep.com
Country: China
ProdList: 64
Advantage: 58

Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd.

Tel: 0531-58897130 15508676053
Email: drug_impurity@sdcclh.com
Country: China
ProdList: 2268
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 13316949107 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 9564
Advantage: 58

Less

View Lastest Price from tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid 1,1-dimethylethyl ester 1201187-44-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-09-19

Wuhan Biocar Pharmacy CO.,Ltd.

Product: tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate 1201187-44-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 600kg
Release date: 2025-02-25

Henan Aochuang Chemical Co.,Ltd.

Product: tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate 1201187-44-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

1201187-44-1, tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamateRelated Search:

tert-Butyl (4-methylpiperidin-4-yl)carbamate tert-Butyl 3-oxoazetidine-1-carboxylate tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Upadacitinib tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate tert-Butyl 3-phenyl-L-alaninate hydrochloride tert-Butyl 3-allyl-4-oxopyrrolidine-1-carboxylate (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester (3R,4S)-1-[(benzyloxy)carbonyl]-4-ethylpyrrolidine-3-carboxylic acid 5-[(4-methylphenyl)sulfonyl]-5H-Pyrrolo[2,3-b]pyrazin-2-amine 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate

Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester

tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate

Intermediate of Upadacitinib (ABT-494)

2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate

Upadacitinib intermediate2

2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...

Upadacitinib Impurity 3

Upadacitinib Intermediate4

N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester

Upadacitinib Intermediates

1,1-Dimethylethyl N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbama

5-toluenesulfonyl-5H-pyrrolo [2,3-B] pyrazine-2-aminoformic acid tert butyl ester

tert-butyl 5-tosyl-5H-pyrrolo[2,3-blpyrazin-2-ylcarbamate

1201187-44-1