ChemicalBook > CAS DataBase List > Sineptina

Sineptina

Product Name
Sineptina
CAS No.
1392-21-8
Chemical Name
Sineptina
Synonyms
KITASAMYCIN;LEUCOMYCIN HYDRATE;KITASAMYCIN BASE;c637;Ayermycin;Sineptina;Syneptine;ayermicina;guitamycin;FLUPHEZINE
CBNumber
CB1338872
Molecular Formula
C35H59NO13
Formula Weight
701.84186
MOL File
1392-21-8.mol
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Sineptina Property

Melting point:
128-145 °C
storage temp. 
Sealed in dry,2-8°C
solubility 
ethanol: 50 mg/mL, clear to slightly hazy, light-yellow
form 
Solid
color 
White to Off-White
Merck 
14,5453
InChIKey
XYJOGTQLTFNMQG-XMWOZFRUSA-N
CAS DataBase Reference
1392-21-8
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Safety

Safety Statements 
24/25
WGK Germany 
1
RTECS 
WG9400000
F 
10
HS Code 
29419090
Toxicity
mouse,LD50,intraperitoneal,1758mg/kg (1758mg/kg),Drugs in Japan Vol. -, Pg. 354, 1995.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
31721
Product name
Leucomycin hydrate
Packaging
250mg
Price
$114
Updated
2022/05/15
TRC
Product number
L330320
Product name
Leucomycins(>85%)
Packaging
5g
Price
$50
Updated
2021/12/16
TRC
Product number
L330320
Product name
Leucomycins(>85%)
Packaging
10g
Price
$85
Updated
2021/12/16
Usbiological
Product number
453649
Product name
Leucomycin A1
Packaging
1mg
Price
$581
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003149
Product name
LEUCOMYCIN HYDRATE
Purity
95.00%
Packaging
5G
Price
$810.6
Updated
2021/12/16
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Sineptina Chemical Properties,Usage,Production

Description

Kitasamycin, formerly called leucomycin, was found in the culture broth of Streptoverticillium kitasatoensis by Hata et al. of the Kitasato Institute, Japan, in 1953. This was the first macrolide antibiotic with a 16-membered lactone constituent. Kitasamycin is a complex of eight leucomycin A components and is used in its base and ester forms to treat gram-positive bacterial and gram-negative coccal infections, as well as infections of Mycoplasma, Spirochaeta, and Treponema by injection or by oral topical administration.

Chemical Properties

White or yellow crystalline powder, odorless, bitter taste. Easily soluble in methanol, ethanol, acetone, ether and chloroform, insoluble in water, oral LD50 in mice (3.8±0.3)g/kg, oral LD50 in rats >8g/kg.

Uses

Leucomycins (>85%) (cas# 1392-21-8) is a compound useful in organic synthesis.

Uses

Sineptina is a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. The complex contained over 14 components with analogues A1, A4, A5, and A13 being the most abundant analogues.Sineptina is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma.

Definition

ChEBI: Leucomycin V is a macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens. It has a role as a bacterial metabolite. It is a leucomycin and a macrolide antibiotic.

Pharmaceutical Applications

A naturally occurring product of Streptomyces kitasatoensis, available in Japan for parenteral and oral use, and as acetylkitasamycin for topical application. Elsewhere it is chiefly used in veterinary medicine.

Sineptina Preparation Products And Raw materials

Raw materials

Butyl acetate Starch

Preparation Products

ROKITAMYCIN
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Sineptina Suppliers

Americas 1 Australia 1 Belgium 1 Brazil 1 Canada 2 China 224 Czech Republic 1 Europe 3 France 3 Germany 5 India 9 Japan 4 Philippines 1 Spain 1 Switzerland 3 United Kingdom 6 United States 24 Global 290
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View Lastest Price from Sineptina manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sineptina 1392-21-8
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
≥1320u/mg
Supply Ability
1000KGS
Release date
2021-06-24
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Kitasamycin 1392-21-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-03
Hebei Chuanghai Biotechnology Co,.LTD
Product
Kitasamycin 1392-21-8
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-20

1392-21-8, SineptinaRelated Search:

Hyodeoxycholic acid HYPOCRELLIN A oleandomycin TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) METHYL ISOCYANOACETATE SALCOMINE Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Benzyl isocyanide Cupric acetylacetonate Aluminum acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TERT-BUTYL ISOCYANIDE PHENYLSELENOL 2,4-PENTANEDIONE, SILVER DERIVATIVE Ethyl isocyanoacetate N-BUTYLISOCYANIDE COBALT(II) ACETYLACETONATE

  • LEUCOMYCIN HYDRATE
  • KITASAMYCIN BASE
  • KITASAMYCIN
  • FORMACIDINE
  • ayermicina
  • 2-[6-[[5-[(4,5-dihydroxy-4,6-dimethyl-2-oxanyl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyl-2-oxanyl]oxy]-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
  • Leucomycin complex
  • Kitasamycin Solution, 1000ppm
  • Leucomycin hydrate, >=1300 units/mg
  • c637
  • selectomycin
  • Leucomycin Base
  • Acetylkitasamycin JPXIV
  • Leucomycins
  • Leucomycin (8CI, 9CI)
  • Ayermycin
  • Leucomycin A1
  • Sineptina
  • Stereomycine
  • Syneptine
  • Leucomycin hyd
  • Kitasamycin, mixture of isomers A0-A9
  • Leucomycins (>85%)
  • Leucomycin (technical)
  • Sineptina USP/EP/BP
  • TIANFU-CHE MCAS:1392-21-8 Sineptina
  • Leucomycin (Kitasamycin)
  • Leucomycin (8CI, 9CI, ACI)
  • guitamycin
  • Thiabendazole Impurity 6
  • Kitasamycin, mixture of analogues A0-A9 in methanol
  • Leucomycin hydrate in Acetonitrile
  • C14629600 Leucomycin (technical)
  • Leucomycin (technical mixture)
  • XA14629600ALLeucomycin (technical) 100μg/mLin
  • Leucomycin (technical) 100 μg/mL in Acetonitrile
  • FLUPHEZINE
  • 1392-21-8
  • 178234-34-7
  • C41H69NO13
  • C3742H6169NO1415
  • 70184
  • Antibiotics N-S
  • Antibiotics A to Z
  • Antibiotics
  • BioChemical