Cholesteryl acetate

Product Name: Cholesteryl acetate
CAS No.: 604-35-3
Chemical Name: Cholesteryl acetate
Synonyms: Chol;ACETYL CHOLESTEROL;CHOLESTERYL ACETATE;CHOLESTEROL ACETATE;Chloesteryl acetate;Cholesterin acetate;Cholesterol 3-Acetate;Cholesterol 3β-Acetate;Perampanel Impurity 40;3β-acetoxy-5-cholestene
CBNumber: CB1346745
Molecular Formula: C29H48O2
Formula Weight: 428.69
MOL File: 604-35-3.mol

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Cholesteryl acetate Property

Melting point:: 112-114 °C (lit.)
alpha: -44 º (c=2, CHCl3)
Boiling point:: 483.49°C (rough estimate)
Density: 0.9935 (rough estimate)
refractive index: 1.5045 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: insoluble
form: Solid
color: White to Off-White
optical activity: [α]24/D 44°, c = 2 in chloroform
Water Solubility: insoluble
Merck: 14,2201
BRN: 2064235
Stability:: Hygroscopic
LogP: 10.542 (est)
CAS DataBase Reference: 604-35-3(CAS DataBase Reference)
NIST Chemistry Reference: Cholesteryl acetate(604-35-3)
EPA Substance Registry System: Cholest-5-en-3-ol (3.beta.)-, acetate (604-35-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
TSCA: Yes

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 151114
Product name: Cholesteryl acetate
Purity: 97%
Packaging: 25g
Price: $117
Updated: 2024/03/01

Sigma-Aldrich

Product number: 151114
Product name: Cholesteryl acetate
Purity: 97%
Packaging: 100g
Price: $328
Updated: 2024/03/01

Alfa Aesar

Product number: A15052
Product name: Cholesteryl acetate, 97+%
Packaging: 25g
Price: $56
Updated: 2023/06/20

Alfa Aesar

Product number: A15052
Product name: Cholesteryl acetate, 97+%
Packaging: 100g
Price: $109
Updated: 2023/06/20

Alfa Aesar

Product number: A15052
Product name: Cholesteryl acetate, 97+%
Packaging: 500g
Price: $458
Updated: 2023/06/20

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Cholesteryl acetate Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powder or needles

Uses

Cholesteryl acetate is used in cosmetics, wrist watches, thermometers, propane tank volume indicators, video displays, pharmaceuticals.

Uses

Cholesteryl acetate is derived from cholesterol, which is a major component of all biological membranes. Approximately 25% of total brain lipid is made up of cholesterol, which is the principal sterol of higher animals. Cholesterol is found in all body tissues, with particularly high concentrations in the brain, spinal cord, and animal fats or oils. Additionally, cholesterol is the main constituent of gallstones.

Preparation

Cholesteryl acetate can be synthesized by the reaction of cholesterol with acetic anhydride in the presence of a catalyst such as pyridine or sulfuric acid. The reaction proceeds as follows:
Cholesterol + Acetic anhydride → Cholesteryl acetate + Acetic acid
The reaction is typically carried out at room temperature or slightly elevated temperatures for several hours. The resulting cholesteryl acetate can be purified by recrystallization from a suitable solvent such as ethanol or acetone.

Definition

ChEBI: Cholesteryl acetate is a cholesterol ester obtained by formal acylation of the hydroxy group of cholesterol by acetic acid. It has a role as a human metabolite. It is a cholesteryl ester and an acetate ester.

Reactions

Monophthalic acid epoxidation of cholesteryl acetate:
A solution of 10 g (0.023 mole) of cholesteryl acetate (mp 112-114°) in ether (50 ml) is mixed with a solution containing 8.4 g (0.046 mole) of monophthalic acid (Chap. 17, Sec. II) in 250 ml of ether. The solution is kept at reflux for 6 hours and then the solvent is removed by distillation (steam bath). The residue is dried under vacuum and digested with 250 ml of dry chloroform. The mixture was filtered to give 6.7 g of phthalic acid (87% recovery). The solvent in the filtrate was evaporated under reduced pressure and the residue was crystallised from 30 ml of methanol to give 6.0 g (58% yield) of β-oxocholesterol acetate. Recrystallisation gives the pure product, melting point 111-112°. Concentration of the filtrate gives 1.55 g (15 per cent yield) of α-oxocholesterol acetate with a melting point of 101-103° after crystallisation from ethanol.

Purification Methods

Crystallise the acetate from n-pentanol or Me2CO. Also purify it by chromatography through silica gel and eluting with MeOH. [Beilstein 6 III 2607, 6 IV 4004.]

Cholesteryl acetate Preparation Products And Raw materials

Raw materials

Acetic anhydride Ammonium chloride Ethyl acetate Cholesterol Sodium bicarbonate Cobalt chloride Magnesium sulfate PETROLEUM ETHER

Preparation Products

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Cholesteryl acetate Suppliers

Belgium 1 Canada 2 China 189 Europe 3 France 1 Germany 7 India 10 Japan 5 Monaco 1 Switzerland 2 United Kingdom 14 United States 44 Global 279

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Japan

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Email: @TCIchemicals.com
Country: Japan
ProdList: 2741
Advantage: 58

Kanto Chemical Co., Inc.

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Email: reag-info@gms.kanto.co.jp
Country: Japan
ProdList: 6756
Advantage: 74

Wako Pure Chemical Industries, Ltd.

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Email: labchem-tec@wako-chem.co.jp
Country: Japan
ProdList: 6819
Advantage: 80

Nacalai Tesque, Inc.

Tel: --
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Email: info-tech@nacalai.co.jp
Country: Japan
ProdList: 6046
Advantage: 75

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View Lastest Price from Cholesteryl acetate manufacturers

Changsha YuTeng New Materials Co., Ltd.

Product: Plant-origin Cholesterol Acetate 604-35-3
Price: US $0.00/g
Min. Order: 500g
Purity: 99%
Supply Ability: 10 kg
Release date: 2024-08-30

Zhengzhou Anbu Chem Co.,Ltd

Product: Cholesteryl acetate 604-35-3
Price: US $0.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2023-06-13

Zhengzhou Anbu Chem Co.,Ltd

Product: Cholesteryl acetate 604-35-3
Price: US $0.00/KG
Min. Order: 0.10000000149011612KG
Purity: 98%
Supply Ability: 100KGS
Release date: 2023-04-14

604-35-3, Cholesteryl acetateRelated Search:

POLY(VINYL ACETATE) Sodium acetate Amyl acetate 1-Methoxy-2-propyl acetate Cholesterol Triacetin Glatiramer acetate Benzyl acetate Ethylene glycol monoethyl ether acetate Pralmorelin 5-Chlorovaleric acid Vinyl acetate [(3S,8S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 2,4-dichlorobenzoate Ammonium acetate Trenbolone acetate Tocopheryl acetate Diphenolic acid 4-(Diethylamino)salicylaldehyde

3-BETA-HYDROXY-5-CHOLESTENE 3-ACETATE

3BETA-ACETOXY-5-CHOLESTENE

CHOLESTEROL ACETATE

CHOLESTERYL ACETATE

(3beta)-Cholest-5-en-3-ol acetate

5-CHOLESTEN-3BETA-OL 3-ACETATE

5-CHOLESTEN-3-BETA-OL ACETATE

5-CHOLESTEN-3B-OL 3-ACETATE

ACETYL CHOLESTEROL

ACETIC ACID CHOLESTEROL ESTER

ACETIC ACID (3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER

(3β)-cholest-5-en-3-ylethanoate

3beta-Acetoxycholest-5-ene

3β-acetoxy-5-cholestene

5-Cholesten-3B-ol, acetate

Cholest-5-en-3beta-ol acetate

Cholest-5-en-3beta-yl acetate

Cholest-5-en-3-ol (3beta)-, acetate

Cholest-5-en-3-ol(3.beta.)-,acetate

CHOLESTERYL ACETATE extrapure

3β-Acetoxy-5-cholestene, 3β-Hydroxy-5-cholestene 3-acetate, 5-Cholesten-3β-ol 3-acetate

(3β)-3-Cholesteryl=acetate

3β-Acetoxy-5(6)-cholestene

Acetic acid cholest-5-en-3β-yl ester

Cholesteryl acetate,3β-Acetoxy-5-cholestene, 3β-Hydroxy-5-cholestene 3-acetate, 5-Cholesten-3β-ol 3-acetate

Cholesterol Acetate (C2)

(3β)-Cholest-5-en-3-ol Acetate

Chol

Cholesterol 3-Acetate

Cholesterol 3β-Acetate

Acetic Acid Cholesterol Ester Acetyl Cholesterol

3b-Acetoxycholest-5-ene

Acetic acid cholesteryl ester

Chloesteryl acetate

CHOLESTERYL ACETATE(REAGENT / STANDARD GRADE)

Cholesteryl acetate, 97+%

3-(-)-Cholesteryl acetate

3β-Acetoxycholest-5-ene

Cholest-5-en-3β-ol acetate

CHOLESTERYL ACETATE (CHOLESTEROL ACETATE)

cholest-5-en-3-ol(3β)-,acetate

Cholest-5-en-3-yl acetate

Cholesterin acetate

3β-Hydroxy-5-cholestene 3-acetate

5-Cholesten-3β-ol 3-acetate

[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate

CHOLESTERYL ACETATE(RG)

5-Cholesten-3beta-Ol 3-Acetat

CHOLESTERYL ACETATE 97%

Cholesterol Acetate &gt

Cholest-5-en-3-ol (3β)-, 3-acetate

9a,11a-dimethyl-1-(6-methylheptan-2-yl)-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl acetate

[(10R,13R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate

(-)-Cholesteryl acetate

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate

Plant-origin Cholesterol Acetate

Perampanel Impurity 40

5-CHOLESTEN-3β-OL ACETATE