LYN PEPTIDE INHIBITOR
- Product Name
- LYN PEPTIDE INHIBITOR
- CAS No.
- 222018-18-0
- Chemical Name
- LYN PEPTIDE INHIBITOR
- Synonyms
- LYN PEPTIDE INHIBITOR;M.W. 2370.91 C115H184N30O24;L-Prolinamide, N-(1-oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-
- CBNumber
- CB1355822
- Molecular Formula
- C115H184N30O24
- Formula Weight
- 2370.92
- MOL File
- 222018-18-0.mol
LYN PEPTIDE INHIBITOR Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- Sequence
- Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
N-Bromosuccinimide Price
- Product number
- 2265
- Product name
- Lynpeptideinhibitor
- Packaging
- 1
- Price
- $371
- Updated
- 2021/12/16
- Product number
- PEP0004504
- Product name
- LYN PEPTIDE INHIBITOR
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.72
- Updated
- 2021/12/16
- Product number
- B5285
- Product name
- Lynpeptideinhibitor
- Packaging
- 1mg
- Price
- $549
- Updated
- 2021/12/16
LYN PEPTIDE INHIBITOR Chemical Properties,Usage,Production
Uses
Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to?βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of ?asthma, allergic, and other eosinophilic disorders[1].
IC 50
IL-5; IL-3
References
[1] T Adachi, et al. The mapping of the Lyn kinase binding site of the common beta subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J Immunol. 1999 Feb 1;162(3):1496-501. PMID:9973406
[2] T Adachi, et al. A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. J Immunol. 1999 Jul 15;163(2):939-46. PMID:10395690
LYN PEPTIDE INHIBITOR Preparation Products And Raw materials
Raw materials
Preparation Products
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