ChemicalBook > CAS DataBase List > ATP disodium salt

ATP disodium salt

Product Name
ATP disodium salt
CAS No.
987-65-5
Chemical Name
ATP disodium salt
Synonyms
ADENOSINE TRIPHOSPHATE DISODIUM;ATP-NA2;ATP DISODIUM SALT;ADENOSINE TRIPHOSPHATE, DISODIUM SALT;ATP 2NA;ATP DISODIUM;Adenosine 5'-triphosphate disodium salt;Adetide;551.145;adetphos
CBNumber
CB1360204
Molecular Formula
C10H17N5NaO13P3
Formula Weight
531.18
MOL File
987-65-5.mol
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ATP disodium salt Property

Melting point:
188～190℃
Density 
1.85 at 20℃
vapor pressure 
0.1Pa at 20-50℃
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
crystalline
color 
White powder
PH Range
2.5 - 3.5
Water Solubility 
Soluble in water
Merck 
155
InChIKey
TTWYZDPBDWHJOR-IDIVVRGQSA-L
LogP
-2.66 at 24℃ and pH7
Surface tension
67.86mN/m at 1.019g/L and 20℃
CAS DataBase Reference
987-65-5(CAS DataBase Reference)
EPA Substance Registry System
Adenosine 5'-(tetrahydrogen triphosphate), disodium salt (987-65-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
AU7417000
F 
10-21
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A6559
Product name
Adenosine 5′-triphosphate disodium salt solution
Purity
Crystalline ATP, HPLC purified, aqueous solution for RNA transcription
Packaging
25μmol
Price
$123
Updated
2024/03/01
Sigma-Aldrich
Product number
119125
Product name
Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade - CAS 987-65-5 - Calbiochem
Purity
Lowmetalsgrade.Speciallyprocessedtoreducelevelsofcontaminatingmetals.
Packaging
1g
Price
$149
Updated
2024/03/01
Cayman Chemical
Product number
14498
Product name
Adenosine 5'-triphosphate (sodium salt)
Purity
≥95%
Packaging
5g
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
14498
Product name
Adenosine 5'-triphosphate (sodium salt)
Purity
≥95%
Packaging
10g
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
14498
Product name
Adenosine 5'-triphosphate (sodium salt)
Purity
≥95%
Packaging
25g
Price
$233
Updated
2024/03/01
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ATP disodium salt Chemical Properties,Usage,Production

Description

ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is an organic sodium salt. It consists of an ATP and a ({(2R,3S,4R,5R)-3,4-dihydroxy-5-(9h -purin-9-yl)oxolan-2-yl)methylphosphonatooxy)phosphonate. It has the role of providing a source of energy for cells and is a central component of energy storage and metabolism in the body. ATP disodium salt is an important endogenous signalling molecule in immunity and inflammation. It is an important component in the study of various physiological and biochemical processes. It is involved in a variety of cellular functions such as muscle contraction, nerve impulse transmission and membrane transport, making it a fundamental molecule for understanding biological mechanisms. It can also be used to photometrically determine Luc activity in cell extracts.

Chemical Properties

White powder

Uses

A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. ATP Disodium Salt is used in the synthetic preparation of ribose-modified deoxyadenosine bisphosphate analogues as P2Y1 receptor ligands.

Uses

In biochemical research. To inhibit enzymatic browning of raw edible plant materials, such as sliced apples, potatoes, etc.

Uses

Adenosine 5'-triphosphate disodium salt is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.ATP (Adenosine-Triphosphate) transports chemical energy within cells for metabolism. ATP (Adenosine-Triphosphate) is produced by photophosphoryla.

Biological Activity

P2 purinoceptor agonist.

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

in vitro

ATP disodium salt (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on activating the NLRP3 inflammasome in HGFs.
ATP disodium salt (2 mM; 0.5-24 hours) induces the secretion of interleukin 1β, KC, and MIP-2 from bone marrow-derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt stimulates cytokine and chemokine secretion, and inflammasome activation, directly and indirectly, induces in vitro neutrophil chemotaxis.

in vivo

ATP disodium salt (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.

storage

Store at -20°C

Toxicity evaluation

ATP disodium salt was administered by gavage to rats for 90 consecutive days at doses of 0 (control), 500, 1000, and 2000 mg kg BW?1·d?1 (n = 10 per sex/group). Subchronic administration of ATP was well tolerated at all dose levels. Body weights and feed consumption body weight gains were similar between ATP-treated and control rats. Minor differences were seen in hematology and blood chemistry; however, these changes were not dose-related and, therefore, not of biological or toxicological significance. Only one difference was observed in absolute organ weights; females of the high dose had increased kidney and increased relative kidney and liver weights; however, these differences were not seen in males nor appeared to be dose-related[1].

References

[1] Ralf Jger, John C. Fuller Jr., Martin Purpura . “Subchronic (90-Day) repeated dose toxicity study of disodium adenosine-5′-triphosphate in rats.” Regulatory Toxicology and Pharmacology 116 (2020): Article 104760.

ATP disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ATP disodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.
Product
Adenosine 5'-triphosphate disodium salt,ATP-Na2; 5'-ATP-Na2 987-65-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.0%min. HPLC
Supply Ability
10000
Release date
2024-09-20
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Adenosine 5-Triphosphate Disodium Salt 987-65-5
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-19
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Adenosine Disodium Triphosphate 987-65-5
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-28

987-65-5, ATP disodium saltRelated Search:

Ethylenediaminetetraacetic acid disodium salt Cyclic AMP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) Sodium chloride Clodronate disodium Pamidronate disodium salt Dibutyryl adenosine cyclophosphate calcium Adenosine triphosphate Sodium Phosphate, Dibasic ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& Cytidine 5'-triphosphate disodium salt Cytidine-5'-triphosphate disodium salt dihydrate ADENOSINE 5'-DIPHOSPHATE DI(MONOCYCLOHEXYLAMMONIUM) SALT Sodium Monofluorophosphate Adenosine-5'-diphosphate trilithium salt NADP sodium salt Guanosine-5'-triphosphoric aicd disodium salt Uridine-5'-triphosphoric acid trisodium salt Atp Disodium Salt

  • ADENOSINE TRIPHOSPHATE DISODIUM
  • ADENOSINE TRIPHOSPHATE, DISODIUM SALT
  • ADENYLPYROPHOSPHORIC ACID DISODIUM SALT
  • ADENOSINE-5'-TRIPHOSPHATE HYDRATE DISODIUM SALT
  • ADENOSINE-5'-TRIPHOSPHATE NA2-SALT
  • ADENOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM
  • ADENOSINE-5'-TRIPHOSPHORIC ACID DISODIUM DIHYDROGEN SALT
  • ADENOSINE 5'-TRIPHOSPHORIC ACID DISODIUM SALT
  • ADENOSINE-5'-TRIPHOSPHATE TRIHYDRATE DISODIUM SALT
  • Adenosine -5'- Triphosphate Disodium Salt（ATP-Na2）
  • disodiumatp
  • disodiumdihydrogenatp
  • adenoshine-5'-triphosphate di-sodium salt
  • ADENOSINE 5'-TRIPHOSPHATE DISODIUMGRADE II FROM
  • ADENOSINE 5'-TRIPHOSPHATE DISODIUMGRADE I FROM
  • ADENOSINE 5'-TRIPHOSPHATE DISODIUMSIGMAU LTRA FROM
  • ADENOSINE 5'-TRIPHOSPHATE DISODIUM CELL CULTURE TES
  • ADENOSINE-5'-TRIPHOSPHORIC ACID DISODIUM SALT BIOSYNTH
  • Adenosine5-TriphosphoricAcidDisodiumSalt(Atp)
  • Atp,Disodium,Trihydrate
  • ADENOSINE-5-DIPHOSPHORIC ACID DI SODIUIM SALT (A.T.P.)
  • Adenosintriphosphat
  • Adenosintriphosphate
  • Adenosine 5'-triphosphate disodiuM salt SynonyMs ATP disodiuM salt
  • ADENOSINE TRIPHOSPHATE DISODIUM SALT (ATP NA)
  • 5'ADENOSINETRIPHOSPHORIC ACID DISODIUM SALT HYDRATE
  • Adenosine-5'-triphosphoric
  • adenosine 5'-triphosphate disodium salt solution
  • Adenosine Disodium Triphosphate Tablets
  • Adenosine 5'-(tetrahydrogen triphosphate), sodium salt (1:2)
  • HEPES FREE ACID HIGH PURITY GRADE
  • ATPNa2 ( Adenosine-5'-triphosphate,disodium salt,trihydrate)
  • Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade
  • 5'-ATP,Na3
  • Adenosine Triphosphate Disdium Salt
  • ADENOSINE-5'-PHOSPHORIC ACID, DISODIUM SALT
  • ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE) DISODIUM
  • ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE) DISODIUM SALT
  • ADENOSINE 5'-TRIPHOSPHATE (ATP) STANDARD DISODIUM SALT
  • ADENOSINE 5'-TRIPHOSPHATE, DISODIUM
  • ADENOSINE 5'-TRIPHOSPHATE DISODIUM SALT TRIHYDRATE
  • ADENOSINE 5'-TRIPHOSPHATE, DISODIUM, TRIHYDRATE
  • 5'-ADENOSINETRIPHOSPHORIC ACID DISODIUM SALT
  • 5'-ATP 2NA 3H2O
  • ATP 2NA
  • ATP, 2NA, TRIHYDRATE
  • ATP DISODIUM
  • ATP DISODIUM SALT
  • ATP DISODIUM SALT TRIHYDRATE
  • ATP-NA2
  • ATP, NA2H2
  • ATP TRIHYDRATE
  • ATP TRIHYDRATE DISODIUM SALT
  • adetphos
  • disodiumadenosine5’-triphosphate
  • disodiumadenosinetriphosphate
  • Adenosine 5'-triphosphate disodium salt
  • ADENOSINE TRIPHOSPHATE DISODIUM (ATP DISODIUM SALT)