ChemicalBook > CAS DataBase List > TRYPROSTATIN A

TRYPROSTATIN A

Product Name
TRYPROSTATIN A
CAS No.
171864-80-5
Chemical Name
TRYPROSTATIN A
Synonyms
TPS-A;TRYPROSTATIN B;TRYPROSTATIN A;Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-[[6-methoxy-2-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]methyl]-, (3S,8aS)-
CBNumber
CB1458246
Molecular Formula
C22H27N3O3
Formula Weight
381.47
MOL File
Mol file
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TRYPROSTATIN A Property

Melting point:
119-120 °C
Boiling point:
666.4±55.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
pka
12.99±0.40(Predicted)
form 
White powder.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0004339
Product name
TRYPROSTATIN A
Purity
95.00%
Packaging
5MG
Price
$496.63
Updated
2021/12/16
Arctom
Product number
AS236598
Product name
TryprostatinA
Packaging
5mg
Price
$506
Updated
2021/12/16
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TRYPROSTATIN A Chemical Properties,Usage,Production

Uses

Tryprostatin A is an inhibitor of the mammalian cell cycle. Tryprostatins A can be isolated from the secondary metabolites of a marine fungal strain BM939[1].

Definition

ChEBI: Tryprostatin A is a cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at positions 2 and 6 on the indole ring by prenyl and methoxy groups respectively. It has a role as a breast cancer resistance protein inhibitor. It is a dipeptide, a member of indoles, a pyrrolopyrazine, an aromatic ether and an indole alkaloid. It is functionally related to a brevianamide F.

References

[1] CHENG-BIN CUI, et al. Tryprostatins A and B, Novel Mammalian Cell Cycle Inhibitors Produced by Aspergillus fumigatus. The Journal of Antibiotics. 1995, 48.

TRYPROSTATIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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171864-80-5, TRYPROSTATIN ARelated Search:

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  • TRYPROSTATIN A
  • TRYPROSTATIN B
  • TPS-A
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-[[6-methoxy-2-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]methyl]-, (3S,8aS)-
  • 171864-80-5