Star anise oil Content analysis Toxicity Usage limit Chemical properties Uses Production method
ChemicalBook > CAS DataBase List > 4-Methoxybenzyl alcohol

4-Methoxybenzyl alcohol

Star anise oil Content analysis Toxicity Usage limit Chemical properties Uses Production method
Product Name
4-Methoxybenzyl alcohol
CAS No.
105-13-5
Chemical Name
4-Methoxybenzyl alcohol
Synonyms
(4-METHOXYPHENYL)METHANOL;ANISYL ALCOHOL;ANISE ALCOHOL;ANISIC ALCOHOL;P-ANISYL ALCOHOL;FEMA 2099;ANISALKOHOL;P-ANISIC ALCOHOL;PAAL;ANIS ALCOHOL
CBNumber
CB1494730
Molecular Formula
C8H10O2
Formula Weight
138.16
MOL File
105-13-5.mol
More
Less

4-Methoxybenzyl alcohol Property

Melting point:
22-25 °C (lit.)
Boiling point:
259 °C (lit.)
Density 
1.113 g/mL at 25 °C (lit.)
vapor pressure 
0.24-0.53Pa at 25℃
FEMA 
2099 | ANISYL ALCOHOL
refractive index 
n20/D 1.544(lit.)
Flash point:
230 °F
storage temp. 
-20°C
solubility 
alcohol: freely soluble
form 
Liquid After Melting
pka
14.43±0.10(Predicted)
Specific Gravity
1.108
color 
Clear colorless to yellow
PH
6.3 (10g/l, H2O, 20℃)
Odor
at 100.00 %. sweet powdery hawthorn lilac rose floral hyacinth
Odor Type
powdery
explosive limit
0.9-7.3%(V)
Water Solubility 
insoluble
Merck 
14,665
JECFA Number
871
BRN 
636654
InChIKey
MSHFRERJPWKJFX-UHFFFAOYSA-N
LogP
-0.08-1.05 at 24-27℃
CAS DataBase Reference
105-13-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanol, 4-methoxy-(105-13-5)
EPA Substance Registry System
4-Methoxybenzenemethanol (105-13-5)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-63-62-41-37/38-20/21/22
Safety Statements 
26-36-45-36/37/39
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
RTECS 
DO8925000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29094990
Toxicity
LD50 orally in rats: 1.2 ml/kg (Woodart)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W209910
Product name
Anisyl alcohol
Purity
natural, ≥98%, FG
Packaging
100g
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
W209910
Product name
Anisyl alcohol
Purity
natural, ≥98%, FG
Packaging
1kg
Price
$1060
Updated
2024/03/01
Sigma-Aldrich
Product number
W209902
Product name
Anisyl alcohol
Purity
≥98%, FCC, FG
Packaging
1kg
Price
$90.8
Updated
2024/03/01
Sigma-Aldrich
Product number
W209902
Product name
Anisyl alcohol
Purity
≥98%, FCC, FG
Packaging
10Kg
Price
$590
Updated
2024/03/01
Sigma-Aldrich
Product number
W209902
Product name
Anisyl alcohol
Purity
≥98%, FCC, FG
Packaging
25kg
Price
$1470
Updated
2024/03/01
More
Less

4-Methoxybenzyl alcohol Chemical Properties,Usage,Production

Star anise oil

Star anise oil, also known as anise oil, appears as colorless transparent or light yellow liquid at above 20°C. When the temperature will drop, there will be sheet crystal precipitate with anise aroma and sweetness of the anethole. It is slightly soluble in water and easily soluble in ethanol, ether and chloroform. It belongs to Illicium Linn, magnoliaceae. The fruit is an aggregate fruit, being octagonal, therefore it is commonly known as star anise, also known as aniseed. Star anise oil is a kind of aromatic oil with complex composition, being volatile oil and a little sticky. Its color is gray for the best case while is yellow for slightly worse cases. It tastes sweet and tingling with a strong aroma of star anise. It is agitated at a temperature of 10 to 15 °C upon stirring. Its main ingredient is trans-anethole with a content of up to 80%. It also contains α-pinene, limonene, linalool, safrole, anisic aldehyde, anisone, 4-terpineol, artemisia capillaris, anisaldehyde and other ingredients. Anise oil is a kind of aromatic oil which is strongly technical and is not easy to identify using chemical equipment. The current producing area is still mainly through the buyer with the naked eye and nose smell to identify the quality of star anise.
Anise oil, in the spice industry, is mainly used to extract anethole brain and re-synthesis of anisaldehyde and anisol alcohol (p-methoxybenzyl alcohol, 4-methoxybenzyl alcohol). Some of the spices are widely used in toothpaste, food and soap and cosmetics fragrance. The fruit is commonly used in people's food seasoning spices. At the same time, the anise oil is the major raw material for the synthesis of negative hormone estrone in the pharmaceutical industry. As the octagonal oil is lighter than water, so it can be suspended in the water. The water obtained after oil and water separation contains anise oil after the anise oil returns to the distillation pot for re-distillation to improve the oil yield.

Content analysis

According to the Total Alcohol Assay (OT-5): the amount of acetylated alcohol used for saponification was 1.5 g. The equivalent factor (e) in the calculation is 69.09, or by gas chromatographic nonpolar column method in GT-10-4.

Toxicity

ADI 1 mg/kg (CE);
LD50 1200 mg/kg (rat, oral);

Usage limit

FEMA (mg/kg): soft drink 7.4; cold drink 8.0; candy 11; baked goods 12; pudding class 1.9.
Take moderate as limit (FDA § 172.515, 2000).

Chemical properties

It appears as colorless to slightly yellow liquid or opaque crystals with the relative density of 1.110-1.120, refractive index of 1.543-1.545, the boiling point of about 258-259 °C, freezing point> 23.5 °C, the flash point of 100 °C above and insoluble in water. It is soluble in the same volume of 50% alcohol with an acidity value of 1.0.
It mainly has fennel aroma with a slight cream fragrance and fragrant background. Aromatic odor is mild and can stay long.

Uses

1. 4-Methoxybenzyl alcohol mainly used in floral flavor with fragrance flavor, such as hawthorn flowers, jasmine, acacia, shy flowers, acacia, lilac, lily of the valley, violet, magnolia, sunflower, daffodils and so on. It can also be used for the need for chypre spices with vanilla flavor to coordinate the aroma and increase the aroma of beans. It can also be used for chocolate, cocoa and fresh fruit flavor.
2. GB 2760-1996 provides as allowable food flavors. It is mainly used for the preparation of vanilla, chocolate, cocoa, almonds, peaches and other flavor.
3. It is used for the preparation of drugs and spices.
4. It is used as pharmaceutical intermediates.
5. 4-Methoxybenzyl alcohol has a slightly sweet aroma of anise, commonly used in the preparation of jasmine, lilac and other flavors, suitable for deployment of perfume. The goods are allowable food spices provided in China's GB2760-86. It is mainly used to formulate the flavor of vanilla, chocolate, cocoa, almonds and peaches. It can also be used in organic synthesis and as a solvent.
6. It is used as moxonidine intermediates.
7. It is alcohol synthesis spices. It is mainly used as the blending spices of jasmine, cloves, fragrant peas, gardenia and other flavors for perfume and other cosmetics.
8. It can provide the temporary protection for the carbohydrate anti-OH-group.

Production method

It is obtained through the anisaldehyde reduction. The anise, formaldehyde and sodium hydroxide are subject to Cannizzaro reaction in the ethanol to generate p-methoxybenzyl alcohol. After distilling to recycle the ethanol, the resulting oil layer is extracted with benzene, acidified with acetic acid, neutralized by sodium hydrogencarbonate to a weak basicity, washed with water to neutral, then distillation to recover benzene with the residue subjecting to distillation under reduced pressure to obtain p-methoxy Benzyl alcohol.
In methanol solution, apply potassium hydroxide solution for treatment of the mixture of anisaldehyde and formaldehyde, getting mixture of anole alcohol and formic acid. Apply benzene extraction and then purify through distillation.
Use platinum as a catalyst and ferrous chloride as a reductant, obtain it through anisidine hydrogenation.

Chemical Properties

Anise Alcohol occurs in vanilla pods and in anise seeds. It is a colorless liquid with a sweet, floral, slightly balsamic odor.
Insoluble in water, poorly soluble in Propylene glycol and Glycerin soluble in alcohol and oils.

Chemical Properties

CLEAR COLOURLESS TO YELLOWISH LIQUID AFTER MELTING

Chemical Properties

Anisyl alcohol has a floral odor with sweet, fruity (peach) taste.

Occurrence

Reported found in anise (Pimpinella anisum L.), honey, Bourbon vanilla (Vanilla planifolia Andrews), Tahiti vanilla (Vanilla tahitensis Moore), Illicium verum and tomato.

Uses

4-Methoxybenzyl Alcohol is used in the preparation of semiconductors, nanosheets and nanocrystals. Also is used as a reagent for various chemical organic reactions such as in the synthesis of quinolines. It is used as a fragrance and flavorant. It is used to study the photo catalytic oxidation of 4-methoxybenzyl alcohol to p-anisaldehyde.

Uses

4-Methoxybenzyl alcohol was used to study the photocatalytic oxidation of 4-methoxybenzyl alcohol to p-anisaldehyde.

Definition

ChEBI: 4-Methoxybenzyl alcohol is a member of benzyl alcohols.

Preparation

By reduction from anisic aldehyde

Taste threshold values

Taste characteristics at 10 ppm: spice, anise, vanilla, balsamic and powdery

Synthesis Reference(s)

Synthetic Communications, 18, p. 613, 1988 DOI: 10.1080/00397918808064019
Tetrahedron Letters, 32, p. 3243, 1991 DOI: 10.1016/S0040-4039(00)79734-6

General Description

Anisyl alcohol is a volatile aromatic compound mainly found in vanilla extracts and anise oil. It is used as a flavoring agent and fragrance ingredient.

Hazard

Extremely toxic.

Contact allergens

As a fragrance allergen, anisyl alcohol has to be mentioned by name in cosmetics within the EU.

Safety Profile

Moderately toxic by ingestion. A skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALCOHOLS.

4-Methoxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Ferrous chloride p-Anisaldehyde Platinum

Preparation Products

Anisyl acetate
More
Less

4-Methoxybenzyl alcohol Suppliers

Americas 1 Australia 1 Belgium 5 Canada 2 China 434 Europe 6 France 5 Germany 12 India 73 Ireland 1 Italy 2 Japan 6 Poland 1 Slovakia 1 South Korea 3 Spain 3 Switzerland 2 Ukraine 1 United Kingdom 21 United States 80 USA 1 Global 661
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
AccuStandard Inc
Tel
--
Fax
--
Email
info@bester.nl
Country
United States
ProdList
5300
Advantage
76
Auro Chemicals
Tel
--
Fax
--
Email
customerservice@aurochemicals.com
Country
United States
ProdList
246
Advantage
58
Advanced Biotech - ABT
Tel
--
Fax
--
Country
United States
ProdList
260
Advantage
58
Penta Manufacturing Company (a division of Penta International Corporation)
Tel
--
Fax
--
Email
@pentamfg.com
Country
United States
ProdList
901
Advantage
58
Nice Group Inc
Tel
--
Fax
--
Email
Amy@nicegroupinc.com
Country
United States
ProdList
134
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Citrus and Allied Essences Ltd.
Tel
--
Fax
--
Email
galloca@citrusandallied.com
Country
United States
ProdList
90
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Taytonn ASCC Pte Ltd
Tel
--
Fax
--
Email
info@taytonnascc.com
Country
United States
ProdList
742
Advantage
58
Lluch Essence S.L.
Tel
--
Fax
--
Email
web@lluche.com
Country
United States
ProdList
2352
Advantage
58
Prodasynth
Tel
--
Fax
--
Email
info@prodasynth.com
Country
United States
ProdList
423
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Elan Chemical Inc.
Tel
--
Fax
--
Email
sales@elan-chemical.com
Country
United States
ProdList
114
Advantage
65
Excellentia International
Tel
--
Fax
--
Email
info@excellentiaint.com
Country
United States
ProdList
567
Advantage
58
Jiangyin Healthway International Trade Co., Ltd
Tel
--
Fax
--
Email
info@healthwaychem.com
Country
United States
ProdList
1006
Advantage
58
Fleurchem, Inc.
Tel
--
Fax
--
Email
info@fleurchem.com
Country
United States
ProdList
790
Advantage
58
Alfrebro LLC/ Archer Daniels Midland Company
Tel
--
Fax
--
Email
sforbis@alfrebro.com
Country
United States
ProdList
768
Advantage
58
M&U International LLC
Tel
--
Fax
--
Email
sales@mu-intel.com
Country
United States
ProdList
2011
Advantage
58
Global Essence Inc.
Tel
--
Fax
--
Email
info@globalessenceuk.com
Country
United States
ProdList
758
Advantage
58
The Lermond Company
Tel
--
Fax
--
Email
info@lermond.com
Country
United States
ProdList
763
Advantage
58
R C Treatt and Co Ltd
Tel
--
Fax
--
Email
enquiries@treatt.com
Country
United States
ProdList
1690
Advantage
58
WholeChem, LLC
Tel
--
Fax
--
Email
info@wholechem.com
Country
United States
ProdList
814
Advantage
58
Elan Inc.
Tel
--
Fax
--
Email
dpimentel@elan-chemical.com
Country
United States
ProdList
116
Advantage
58
Advanced Biotech. Inc.
Tel
--
Fax
--
Email
info@adv-bio.com
Country
United States
ProdList
1121
Advantage
58
Moellhausen S.P.A.
Tel
--
Fax
--
Country
United States
ProdList
1676
Advantage
58
PerfumersWorld Ltd.
Tel
--
Fax
--
Email
pwenquiries@perfumersworld.com
Country
United States
ProdList
723
Advantage
58
NATURAL ADVANTAGE
Tel
--
Fax
--
Email
customerservice@natural-advantage.net
Country
United States
ProdList
401
Advantage
51
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
Sunaux International
Tel
--
Fax
--
Email
johnjft@sunaux.com
Country
United States
ProdList
581
Advantage
58
Pell Wall Perfumes
Tel
--
Fax
--
Email
//pellwall.com/contact-us/
Country
United States
ProdList
559
Advantage
58
Indukern, S.A. F&F Ingredients Division
Tel
--
Fax
--
Email
info@indukern.es
Country
United States
ProdList
1321
Advantage
58
Odowell Co.,ltd
Tel
--
Fax
--
Email
info@odowell.com
Country
United States
ProdList
62
Advantage
58
Vigon International
Tel
--
Fax
--
Email
sales@vigon.com
Country
United States
ProdList
1776
Advantage
58
Beijing Lys Chemicals Co, LTD.
Tel
--
Fax
--
Email
jiayanyong@lyschem.com
Country
United States
ProdList
710
Advantage
58
Augustus Oils Ltd
Tel
--
Fax
--
Email
essentials@augustus-oils.ltd.uk
Country
United States
ProdList
1404
Advantage
58
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
Ernesto Ventós S.A.
Tel
--
Fax
--
Email
info@ventos.com
Country
United States
ProdList
2257
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
More
Less

View Lastest Price from 4-Methoxybenzyl alcohol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Methoxybenzyl alcohol 105-13-5
Price
US $0.00/kg
Min. Order
1000kg
Purity
98.0%
Supply Ability
100ton/month
Release date
2023-01-14
Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-Methoxybenzyl alcohol 105-13-5
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-18
Hebei Weibang Biotechnology Co., Ltd
Product
4-Methoxybenzyl alcohol 105-13-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01

105-13-5, 4-Methoxybenzyl alcoholRelated Search:

2-Isopropyl-N,2,3-trimethylbutyramide (Trifluoromethoxy)benzene Phenethyl alcohol Anise oil 4-Methoxybenzylamine Ethyl acetate Anisole 4-Methoxybenzylchloride 4-Nitrobenzyl alcohol Benzyl alcohol p-Anisidine 4-Methoxybenzoic acid 4'-Methoxyacetophenone 4-Methoxybenzyl cyanide Methoxypropiophenone 4-Formylbenzoic acid 4-Methoxyphenethylamine 4-Methoxybenzoyl chloride

  • 4-Methoxybenzylalkohol
  • ANISALKOHOL
  • 4-METHOXYBENZYL ALCOHOL / 4-METHOXYPHENYLMETHANOL
  • 4-methoxy-benzenemethano
  • 4-Methoxybenzenemethanol
  • 4-methoxy-Benzenemethanol
  • Benzenemethanol,4-methoxy-
  • Benzyl alcohol, p-methoxy-
  • p-Anisol alcohol
  • p-anisolalcohol
  • p-Methioxybenzylalcohol
  • 38) 4-METHOXY BENZYL ALCOHOL
  • p-ANISYL ALCOHOL pure
  • 4-Methoxybenzyl alcohol, Reagent Grade
  • 4-Methoxybenzyl alcohol, p-Anisyl alcohol, Anis alcohol, Anise alcohol
  • p-Anisyl alcohol, Anis alcohol, Anise alcohol
  • 4-(Hydroxymethyl)anisole
  • 4-Methoxy-a-hydroxytoluene
  • p-Anisalcohol
  • Anysyl alcohol
  • 4-Methoxybenzyl alcohol (p-Anisic alcohol, 99.0%)
  • 4-Methoxybenzyl alcohol,98%
  • METHOXYBENZYL ALCOHOL, 4- (ANISYL ALCOHOL)(SG)
  • p-Anisyl alcohol 2g [105-13-5]
  • Anisyl alcohol,4-Methoxybenzyl alcohol, p-Anisyl alcohol, Anis alcohol, Anise alcohol
  • 4-Methoxybenzyl alco
  • Of Methoxybenzyl alcohol
  • 4-Methoxybenzyl alcohol, 98% 100GR
  • 4-Methoxybenzyl alcohol, 98% 500GR
  • Anise Alcohol Anisyl Alcohol
  • 4-Methoxybenzyl alcohol 105-13-5 p-Anisyl alcohol
  • 4-ANISE ALCOHOL 105-13-5 4-Methoxybenzyl alcohol
  • Anisyl alcohol solution
  • 4-ANISE ALCOHOL
  • 4-ANISYL ALCOHOL
  • 4-ANISIC ALCOHOL
  • (4-METHOXYPHENYL)METHANOL
  • 4-METHOXYBENZYL ALCOHOL
  • ANISYL ALCOHOL
  • ANISIC ALCOHOL
  • ANISE ALCOHOL
  • ANIS ALCOHOL
  • P-ANISE ALCOHOL
  • P-ANISYL ALCOHOL
  • P-ANISIC ALCOHOL
  • PARA METHOXY BENZYL ALCOHOL
  • P-METHOXYBENZYL ALCOHOL
  • RARECHEM AL BD 0083
  • METHOXYBENZYL ALCOHOL
  • METHOXYBENZYLALCOHOL(4-)
  • FEMA 2099
  • p-methoxy-benzylalcoho
  • P-methoxyphenylcarbinol
  • p-Anise alcohol(4-methoxybenzyl alcohol)
  • ANISYL ALCOHOL 98+% FCC
  • ANISYL ALCOHOL NATURAL 98+%
  • 4-Methoxybenzylacohol
  • 4-Methoxybenzyl alcohol, 98% (4-Anisalkohol)