5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE

Product Name: 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
CAS No.: 63810-78-6
Chemical Name: 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
Synonyms: 5-Bromo-4-chloro-2-(methylthio)pyrimidine;5-Bromo-4-chloro-2-(methy...;Pyrimidine, 5-bromo-4-chloro-2-(methylthio)-;5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE;5-Bromo-4-chloro-2-(methylthio)pyrimidine >5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%;5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB1663121
Molecular Formula: C5H4BrClN2S
Formula Weight: 239.52
MOL File: 63810-78-6.mol

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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Property

Melting point:: 45.0 to 49.0 °C
Boiling point:: 309.5±22.0 °C(Predicted)
Density: 1.83±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: -1.97±0.29(Predicted)
color: White to Almost white
InChI: InChI=1S/C5H4BrClN2S/c1-10-5-8-2-3(6)4(7)9-5/h2H,1H3
InChIKey: XVRYJQACDDVZEI-UHFFFAOYSA-N
SMILES: C1(SC)=NC=C(Br)C(Cl)=N1
CAS DataBase Reference: 63810-78-6

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Safety

Risk Statements: 34-22
Safety Statements: 26-36/37/39-45
RIDADR: 2923
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S445827
Product name: 5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: S445827
Product name: 5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE
Purity: Aldrich
Packaging: 50mg
Price: $29.8
Updated: 2024/03/01

TCI Chemical

Product number: B4406
Product name: 5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity: >98.0%(GC)
Packaging: 1g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: B4406
Product name: 5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity: min. 98.0 %
Packaging: 5G
Price: $162
Updated: 2025/07/31

TCI Chemical

Product number: B4406
Product name: 5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity: min. 98.0 %
Packaging: 5G
Price: $162
Updated: 2025/07/31

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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

81560-03-4

63810-78-6

Step 3, Preparation of 5-bromo-4-chloro-2-methylthiopyrimidine: 5-bromo-2-(methylthio)pyrimidin-4(3H)-one (110 g) was dissolved in pyridine (400 g) and heated to 80°C. Phosphorus trichloride (100 g) was added dropwise with stirring. After the dropwise addition, the reaction temperature was maintained and stirring was continued for 5 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and subsequently placed in an ice bath. The pH was adjusted to 8-9 with saturated sodium bicarbonate solution and then extracted with ethyl acetate (500 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure to remove the solvent. The residue was recrystallized by a solvent mixture of petroleum ether and ethyl acetate (1:3, v/v) to give a pale yellow solid powder (98 g) in 83% yield.

References

[1] Patent: CN107488175, 2017, A. Location in patent: Paragraph 0008; 0010
[2] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982, vol. 36, # 1 B, p. 15 - 18

5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Preparation Products And Raw materials

Raw materials

Phosphorus oxitrichloride 2-Thiouracil Bromine Acetic acid Iodomethane

Preparation Products

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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Suppliers

Americas 1 China 153 Europe 1 Germany 1 India 7 Japan 1 United Kingdom 4 United States 23 Global 191

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View Lastest Price from 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-13

Dideu Industries Group Limited

Product: 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-01

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

63810-78-6, 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINERelated Search:

2,4-Diamino-6-hydroxypyrimidine 5-BROMO-4-CHLORO-2-METHANESULFONYL-PYRIMIDINE 5-BROMO-2-(METHYLTHIO)PYRIMIDINE 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 4-Chloro-2-methylthiopyrimidine 5-Bromopyrimidine

5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE

5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%

5-Bromo-4-chloro-2-(methylthio)pyrimidine

Pyrimidine, 5-bromo-4-chloro-2-(methylthio)-

5-Bromo-4-chloro-2-(methy...

5-Bromo-4-chloro-2-(methylthio)pyrimidine &gt

5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE ISO 9001：2015 REACH

63810-78-6

Heterocycle-Pyrimidine series