ChemicalBook > CAS DataBase List > 7-Azaindole

7-Azaindole

Product Name
7-Azaindole
CAS No.
271-63-6
Chemical Name
7-Azaindole
Synonyms
1H-PYRROLO[2,3-B]PYRIDINE;NSC 67063;NSC 77951;7-azindole;7-AZAINDOLE;7-Azaindole99%;7-Dideazapurine;7-Aza-7H-indole;7-AZAINDOLE 98%;7-Azaindole,98%
CBNumber
CB1664663
Molecular Formula
C7H6N2
Formula Weight
118.14
MOL File
271-63-6.mol
More
Less

7-Azaindole Property

Melting point:
105-107 °C (lit.)
Boiling point:
270 °C (753.1004 mmHg)
Density 
1.1151 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
270°C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol
pka
7.69±0.20(Predicted)
form 
Powder
color 
White to off-white
BRN 
109667
InChIKey
MVXVYAKCVDQRLW-UHFFFAOYSA-N
CAS DataBase Reference
271-63-6(CAS DataBase Reference)
NIST Chemistry Reference
1H-Pyrrolo[2,3-b]pyridine(271-63-6)
EPA Substance Registry System
1H-Pyrrolo[2,3-b]pyridine (271-63-6)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-41-37/38-22
Safety Statements 
39-26-36/37/39
WGK Germany 
3
RTECS 
UY8710000
HazardClass 
IRRITANT
HS Code 
29339990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A95502
Product name
7-Azaindole
Purity
98%
Packaging
1g
Price
$47.8
Updated
2024/03/01
TCI Chemical
Product number
P1117
Product name
1H-Pyrrolo[2,3-b]pyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
P1117
Product name
1H-Pyrrolo[2,3-b]pyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$126
Updated
2024/03/01
Alfa Aesar
Product number
L07983
Product name
7-Azaindole, 98%
Packaging
1g
Price
$25.65
Updated
2024/03/01
Alfa Aesar
Product number
L07983
Product name
7-Azaindole, 98%
Packaging
5g
Price
$66.65
Updated
2024/03/01
More
Less

7-Azaindole Chemical Properties,Usage,Production

Chemical Properties

Brown-Cyrstalline Solid

Uses

7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in the treatment.
A heterocyclic molecule that can be utilized as a pharmaceutical building block.
Starting material in a recent synthesis of azaserotonin.

Application

7-Azaindole is a heterocyclic organic compound, which is an organic synthesis intermediate and a pharmaceutical intermediate. It is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, p38 kinase inhibitors, thrombin inhibitors, etc.

Preparation

Synthesis of 7-azaindole: in a single-necked flask, add 2.0 g of 2-amino-3-methylpyridine and 2.5 g of N-Methylformanilide into 40 mL of dichloromethane, and add 3.15 g of PCl with stirring under an ice-water bath. After 4 hours of reaction, the reaction system was slowly poured into 40 mL of ammonia water, and the insoluble matter was removed by suction filtration. The organic layer was separated, washed twice with water, dried over anhydrous sodium sulfate, and evaporated to dryness to obtain 2.91 g of 7-azaindole as a pale yellow solid, with a yield of 70%.

Definition

ChEBI: 1H-pyrrolo[2,3-b]pyridine is a pyrrolopyridine.

Purification Methods

Recrystallise it repeatedly from EtOH, then sublime it in a vacuum [Tokumura et al. J Am Chem Soc 109 1346 1987]. The N-acetate has m 65-66o (from *C6H6), and the picrate has m 232-233o (from Me2CO) [Clemo & Swan J Chem Soc 603 1945, Beilstein 23 III/IV 1105.]

7-Azaindole Preparation Products And Raw materials

Raw materials

Preparation Products

2-(2,3-DIHYDRO-1BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ETHANAMINE 6-BROMO-1H-PYRROLO[2,3-B]PYRIDINE 4-IODO-7-AZAINDOLE 1H-Pyrrolo[2,3-b]pyridine, 4-nitro-, 7-oxide 4-Bromo-7-azaindole 4-Chloro-7-azaindole 7-OXIDE-7-AZAINDOLE 5-Bromo-7-azaindole 2-(2,3-DIHYDRO-1-BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ACETONITRILE 1,7-DIDEAZAADENINE 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO-
More
Less

7-Azaindole Suppliers

Americas 1 Belgium 3 Canada 1 China 442 Europe 4 France 2 Germany 10 India 74 Ireland 1 Japan 6 Poland 1 Slovakia 1 South Korea 2 Switzerland 6 Ukraine 2 United Kingdom 25 United States 92 Global 673
Terma Medicare India Pvt Ltd
Tel
021-52530655 18930806002
Email
yuli@semsstar.com
Country
China
ProdList
135
Advantage
58
ABACHEM
Tel
13816002712
Fax
021-51159188
Email
liu_wj@abachem.com
Country
China
ProdList
46
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-8237592 15562613975
Fax
0531-82375893
Email
3416953599@qq.com
Country
China
ProdList
1193
Advantage
58
LEWOO PHARMATECH (SHANGHAI) CO.,LTD
Tel
15800805830
Fax
021 67898603
Email
miao@lewoopharma.com.cn
Country
China
ProdList
895
Advantage
58
Shanghai Kaipu New Biotechnology Co. , Ltd.
Tel
17821452002
Email
info@shanghaikaipuxin.com
Country
China
ProdList
37
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169097
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
412
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ChangShu Haitian Fine Chemicals Co.,Ltd
Tel
13913622609
Fax
86-512-52893680
Email
sales@haitianchem.cn
Country
China
ProdList
223
Advantage
61
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Bellen Chemistry Co., Ltd.
Tel
010-60400361
Fax
+ 86 10 8947 5062
Email
info@bellenchem.com
Country
China
ProdList
1984
Advantage
65
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1321
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4271
Advantage
65
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Changzhou Standard Chemicals Ltd.
Tel
0519-85607885 13776800733
Fax
+86 519 8552788
Email
email@standardschem.com
Country
China
ProdList
114
Advantage
62
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
1003
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3205
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4001
Advantage
55
Suzhou Guide Fine Material Co.Ltd.
Tel
136-16210669 13914021065
Fax
0512-66627360
Email
sales@guide-chemicals.com
Country
China
ProdList
294
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1927
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
More
Less

View Lastest Price from 7-Azaindole manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
7-Azaindole 271-63-6
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
3000kg
Release date
2024-03-22
Hunan aslsen technology co.,ltd
Product
7-Azaindole 271-63-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2024-03-21
Henan Fengda Chemical Co., Ltd
Product
7-azaindole 271-63-6
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22

271-63-6, 7-Azaindole Related Search:

Pyridine Indometacin Indoline Indole-3-butyric acid Indole-3-acetic acid 7-Benzyloxyindole 7-Fluoroindole 7-Aminoindole 7-Fluorooxindole 7-FLUOROINDOLINE 6-Azaindole 1H-Pyrrolo[3,2-c]pyridine, 5-Azaindole 5-BROMO AZAINDOLE 4-Azaindole 5-Chloro-7-azaindole 2-AMINO-9H-PYRIDO[2,3-B]INDOLE 4,7-Diazaindole 7-Chloro-6-azaindole, 97%

  • 1,7-Diaza-1H-indene
  • 7-Aza-7H-indole
  • 7-Aza-1-pyrindine
  • 7H-Pyrrolo[2,3-b]pyridine
  • Pyrrolo(2,3-b)pyridine
  • 7-AZAINDOLE CRYSTALLINE
  • 7-AZAINDOLE 98%
  • 7-Azaindole99%
  • 7-Azaindole,98%
  • 1H-Pyrrolo[2,3-b]pyridin
  • 7-Dideazapurine
  • 7-Azaindole, 98% 5GR
  • NSC 67063
  • NSC 77951
  • 7-AZAINDOLE FOR SYNTHESIS 1 G
  • 7-Azaindole SynonyMs 1H-Pyrrolo[2,3-b]pyridine
  • 7-Azaindole, 97+%
  • 1H-PYRROLO[2,3-B]PYRIDINE, HYDRATE
  • 7-AZAINDOLE
  • 7-AZAINDOLE, 1H-PYRROLO[2,3,B]PYRIDINE
  • TIMTEC-BB SBB004295
  • 1 H-PYRROLO[2,3:B]PYRIDINE
  • 1H-PYRROLO[2,3-B]PYRIDINE
  • 1H-PYRROLO[2,3]PYRIDINE
  • 1,7-Diazaindene
  • 1,7-Dideazapurine
  • 1H-Pyrrolo[2,3-b]pyridine&gt
  • 7-Azaindole 7-Aza-7H-indole
  • 7-Azaindole CAS NO.271-63-6
  • 1H-Pyrrolo[2,3-b]pyridine (6CI, 8CI, 9CI, ACI)
  • Atogepant Impurity 8
  • 7-azindole
  • 271-63-6
  • 205-981-0
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • blocks
  • IndolesOxindoles
  • Heterocycles
  • Indole Derivatives
  • Pharmaceutical intermediate
  • Heterocycles series
  • Indole
  • Heterocyclic Compounds
  • Indole Series
  • Heterocycle-Indole series
  • Heterocycle-Pyridine series
  • buildingblock
  • Halogenated Heterocycles ,Thiazoles
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals