2-Methoxy-4-nitroaniline
- Product Name
- 2-Methoxy-4-nitroaniline
- CAS No.
- 97-52-9
- Chemical Name
- 2-Methoxy-4-nitroaniline
- Synonyms
- FAST RED B BASE;FAST RED B;RED B BASE;2-AMINO-5-NITROANISOLE;RED B ASE;METHOXY-4-NITROANILINE;4-NITRO-ORTHO-ANISIDINE;AZOIC DIAZO COMPONENT 5;4-NITRO-2-METHOXYANILINE;2-Methoxy-4-nitrobenzenamine
- CBNumber
- CB1693973
- Molecular Formula
- C7H8N2O3
- Formula Weight
- 168.15
- MOL File
- 97-52-9.mol
2-Methoxy-4-nitroaniline Property
- Melting point:
- 140-142 °C(lit.)
- Boiling point:
- 337.07°C (rough estimate)
- Density
- 1,211 g/cm3
- refractive index
- 1.6010 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- 0.2g/l
- form
- Crystalline Powder
- pka
- 1.02±0.10(Predicted)
- color
- Yellow to orange
- PH
- 6.2 (0.2g/l, H2O, 20℃)
- Water Solubility
- slightly soluble
- BRN
- 879619
- InChIKey
- GVBHRNIWBGTNQA-UHFFFAOYSA-N
- CAS DataBase Reference
- 97-52-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 2-methoxy-4-nitro-(97-52-9)
- EPA Substance Registry System
- 2-Methoxy-4-nitroaniline (97-52-9)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-37/39-36/37
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 2
- RTECS
- BZ7170000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29222900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H351Suspected of causing cancer
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 112631
- Product name
- 2-Methoxy-4-nitroaniline
- Purity
- 98%
- Packaging
- 100g
- Price
- $60.2
- Updated
- 2024/03/01
- Product number
- M0118
- Product name
- 2-Methoxy-4-nitroaniline
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $18
- Updated
- 2024/03/01
- Product number
- M0118
- Product name
- 2-Methoxy-4-nitroaniline
- Purity
- >99.0%(GC)
- Packaging
- 500g
- Price
- $193
- Updated
- 2024/03/01
- Product number
- B24220
- Product name
- 2-Methoxy-4-nitroaniline, 99%
- Packaging
- 25g
- Price
- $18.65
- Updated
- 2024/03/01
- Product number
- B24220
- Product name
- 2-Methoxy-4-nitroaniline, 99%
- Packaging
- 100g
- Price
- $32.65
- Updated
- 2024/03/01
2-Methoxy-4-nitroaniline Chemical Properties,Usage,Production
Chemical Properties
2-Methoxy-4-nitroaniline is a yellow to orange crystalline powder. 2-Methoxy-4-nitroaniline (MONA) is a potential nonlinear optical (NLO) material, the N12–O19 bond length of MONA molecule is essentially controlled by the p-character of these hybrid orbitals and also by the nature of the N12–O19 bond. The molecular geometry of the compound is almost planar with the substituents[1].
Uses
2-Methoxy-4-nitroaniline is an important intermediate for preparing organic pigments and color bases of ice dyeing dyestuff. As a benzene dye intermediate, It is generally employed to prepare not only fast pigments but also as a printing and dyeing developer for cotton fabrics. In particular, 2-methoxy-4-nitroaniline is also important in production of some antineoplastic drugs[2-3].
Uses
2-Methoxy-4-nitroaniline is used as a photometric reagent for the determination of ethinylestradiol (ETE), a semi-synthetic estrogen that is widely used in oral contraceptives.
General Description
2-Methoxy-4-nitroaniline is an important inducer of CYP1A2 owing to its small molecular size.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
The metabolism of 2-methoxy-4-nitroaniline (MNA) occurs via the hydroxylation of the phenyl ring to form 6-hydroxy MNA in Harlan Sprague Dawley rats and B6C3F(1)/N mice.
Solubility in organics
The change trend of the solubility magnitude in different monosolvents from high to low was as follows: N-methylpyrrolidone (NMP) > dimethyl sulfoxide (DMSO) > 1,4-dioxane > ethyl acetate > acetonitrile > ethanol > methanol > n-propanol > isopropanol > ethylene glycol (EG) > n-butanol > water[2].
References
[1] Bao Y, et al. 2-Methoxy-4-nitroaniline Solubility in Several Monosolvents: Measurement, Correlation, and Solvent Effect Analysis. Journal of Chemical & Engineering Data, 2020; 65: 757–765.
[2] Degawa M, et al.2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver. Cancer Letters, 1995; 96: 95-98.
[3] Ravikumar C, et al. Electronic absorption and vibrational spectra and nonlinear optical properties of 4-methoxy-2-nitroaniline. Physical Chemistry Chemical Physics, 2010; 12: 9452-9460.
2-Methoxy-4-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxy-4-nitroaniline Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 2-Methoxy-4-nitroaniline manufacturers
- Product
- 2-Methoxy-4-nitroaniline 97-52-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-19
- Product
- Brilliant Red Developing Base 4B 97-52-9
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-08-27
- Product
- Brilliant Red Developing Base 4B 97-52-9
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-09-29