4,5-DIMETHOXY-2-IODOBENZOIC ACID
Uses- Product Name
- 4,5-DIMETHOXY-2-IODOBENZOIC ACID
- CAS No.
- 61203-48-3
- Chemical Name
- 4,5-DIMETHOXY-2-IODOBENZOIC ACID
- Synonyms
- 4,5-DIMETHOXY-2-IODOBENZOIC ACID;Benzoic acid, 2-iodo-4,5-dimethoxy-;2-iodo-4,5-dimethoxybenzenemacetic acid
- CBNumber
- CB1729812
- Molecular Formula
- C9H9IO4
- Formula Weight
- 308.07
- MOL File
- 61203-48-3.mol
4,5-DIMETHOXY-2-IODOBENZOIC ACID Property
- Melting point:
- 206-208°C
- Boiling point:
- 367.9±42.0 °C(Predicted)
- Density
- 1.790±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 3.01±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I705508
- Product name
- 2-Iodo-4,5-dimethoxybenzoicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 003984
- Product name
- 4,5-Dimethoxy-2-iodobenzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $54
- Updated
- 2021/12/16
- Product number
- 2621-H-02
- Product name
- 4,5-Dimethoxy-2-iodobenzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $92
- Updated
- 2021/12/16
- Product number
- 003984
- Product name
- 4,5-Dimethoxy-2-iodobenzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- 2621-H-02
- Product name
- 4,5-Dimethoxy-2-iodobenzoic acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $221
- Updated
- 2021/12/16
4,5-DIMETHOXY-2-IODOBENZOIC ACID Chemical Properties,Usage,Production
Uses
4,5-Dimethoxy-2-iodobenzoic acid is an organic intermediate that can be prepared by first iodinizing 3,4-dimethoxybenzaldehyde to prepare 2-iodo-4,5-dimethoxybenzaldehyde, and then oxidizing it to obtain 4,5-dimethoxy-2-iodobenzoic acid.
Synthesis
To a solution of 3,4-dimethoxybenzaldehyde (2.00 g, 12.0 mmol) in EtOH (100 mL) was added iodine (3.65 g, 14.4 mmol) and silver sulfate (4.49 g, 14.4 mmol) under nitrogen and the mixture was stirred for 3 hours at room temperature. The solvent was removed, water was added and the mixture was extracted with DCM. The organic extract was washed with brine, dried with sodium sulfate and the solvent was removed under reduced pressure. The residue was purified by fast chromatography using petroleum ether/ethyl acetate 2:1 (v:v) as eluent to give 2-iodo-4,5-dimethoxybenzaldehyde (2.81 g, 80%).LC-MS (ES-API); 8.52 min at room temperature; m/zC9H9IO3[M+H]+ calculated value 293.0, measured value 293.0.
At 0C. , a solution of KMnO4 (0.76 g, 4.79 mmol) in water (15 mL) was added dropwise to a stirred solution of 2-iodo-4,5-dimethoxybenzaldehyde (1.0 g, 3.42 mmol) in CH3CN (25 mL). The resulting mixture was stirred at room temperature overnight. After completion of the reaction, the pH was adjusted to <7 with 1 NHCl. The mixture was extracted with DCM, the organic layers were combined, washed with brine, dried over sodium sulfate, and evaporated to give 4,5-dimethoxy-2-iodobenzoic acid (0.89 g, 85%).
4,5-DIMETHOXY-2-IODOBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,5-DIMETHOXY-2-IODOBENZOIC ACID manufacturers
- Product
- 4,5-DiMethoxy-2-iodobenzoic acid 61203-48-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25