Imidapril
- Product Name
- Imidapril
- CAS No.
- 89371-37-9
- Chemical Name
- Imidapril
- Synonyms
- IMIDAPRIL;lmidaprfil;Imidapril HCl;Imidapril Hyd;Imidapril-d5 HCl;(S,S,S)-Imidapril;Imidapril USP/EP/BP;IMidapril (Tanatril);(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
- CBNumber
- CB1780943
- Molecular Formula
- C20H27N3O6
- Formula Weight
- 405.44
- MOL File
- 89371-37-9.mol
Imidapril Property
- Melting point:
- 195-197°C
- alpha
- D20 -71.7° (c = 0.5 in ethanol)
- Boiling point:
- 577.0±60.0 °C(Predicted)
- Density
- 1.266±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- form
- Solid
- pka
- 2.44±0.20(Predicted)
- color
- White to off-white
- CAS DataBase Reference
- 89371-37-9(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- API0006470
- Product name
- IMIDAPRIL
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $191.1
- Updated
- 2021/12/16
- Product number
- API0006470
- Product name
- IMIDAPRIL
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1593.9
- Updated
- 2021/12/16
- Product number
- 11104
- Product name
- ImidaprilHCl
- Packaging
- 50mg
- Price
- $1880
- Updated
- 2021/12/16
- Product number
- 1689B
- Product name
- Imidapril
- Packaging
- 10mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- 1689B
- Product name
- Imidapril
- Packaging
- 25mg
- Price
- $119
- Updated
- 2021/12/16
Imidapril Chemical Properties,Usage,Production
Description
Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at a considerably lower dose than enalapril. This stroke preventive effect has been suggested to be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.
Chemical Properties
White Solid
Originator
Tanabe (Japan)
Uses
Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive
Definition
ChEBI: Imidapril is a member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a dipeptide, a member of imidazolidines, a dicarboxylic acid monoester, a secondary amino compound, an ethyl ester and a N-acylurea.
brand name
Tanatril; Novarok
Imidapril Preparation Products And Raw materials
Raw materials
Preparation Products
Imidapril Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from Imidapril manufacturers
- Product
- Imidapril Hydrochloride 89371-37-9
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500kgs
- Release date
- 2021-10-18
- Product
- Imidapril 89371-37-9
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-09
- Product
- Imidapril 89371-37-9
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 20kg
- Release date
- 2018-07-27