Imidapril

ChemicalBook > CAS DataBase List > Imidapril

Product Name: Imidapril
CAS No.: 89371-37-9
Chemical Name: Imidapril
Synonyms: IMIDAPRIL;lmidaprfil;Imidapril HCl;Imidapril Hyd;Imidapril-d5 HCl;(S,S,S)-Imidapril;Imidapril USP/EP/BP;IMidapril (Tanatril);(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
CBNumber: CB1780943
Molecular Formula: C20H27N3O6
Formula Weight: 405.44
MOL File: 89371-37-9.mol

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Imidapril Property

Melting point:: 195-197°C
alpha: D20 -71.7° (c = 0.5 in ethanol)
Boiling point:: 577.0±60.0 °C(Predicted)
Density: 1.266±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
form: Solid
pka: 2.44±0.20(Predicted)
color: White to off-white
CAS DataBase Reference: 89371-37-9(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0006470
Product name: IMIDAPRIL
Purity: 95.00%
Packaging: 10MG
Price: $191.1
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006470
Product name: IMIDAPRIL
Purity: 95.00%
Packaging: 100MG
Price: $1593.9
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 11104
Product name: ImidaprilHCl
Packaging: 50mg
Price: $1880
Updated: 2021/12/16

AvaChem

Product number: 1689B
Product name: Imidapril
Packaging: 10mg
Price: $59
Updated: 2021/12/16

AvaChem

Product number: 1689B
Product name: Imidapril
Packaging: 25mg
Price: $119
Updated: 2021/12/16

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Imidapril Chemical Properties,Usage,Production

Description

Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at a considerably lower dose than enalapril. This stroke preventive effect has been suggested to be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.

Chemical Properties

White Solid

Originator

Tanabe (Japan)

Uses

Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive

Definition

ChEBI: Imidapril is a member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a dipeptide, a member of imidazolidines, a dicarboxylic acid monoester, a secondary amino compound, an ethyl ester and a N-acylurea.

brand name

Tanatril; Novarok

Imidapril Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide Potassium tert-butoxide Ethyl butyrate Benzyl ester 4-Phenylbutyric acid Propionyl chloride Midazopril hydrochloride 1-Methylpyrazole-4-ethoxycarbonyl-5-ethoxycarbonylsulfonamide Bromobenzene Imidazolidine Aniline D-Alanine Tert-butyl ester Iodomethane (2S)-1-(3-Acetylthio-2-methyl-1-oxopropyl)-L-proline

Preparation Products

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View Lastest Price from Imidapril manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Imidapril Hydrochloride 89371-37-9
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500kgs
Release date: 2021-10-18

Shaanxi Dideu Medichem Co. Ltd

Product: Imidapril 89371-37-9
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-09

Career Henan Chemical Co

Product: Imidapril 89371-37-9
Price: US $20.00/KG
Min. Order: 1KG
Purity: 99.9%
Supply Ability: 20kg
Release date: 2018-07-27

89371-37-9, ImidaprilRelated Search:

Methanol Lithium diisopropylamide Basic Violet 1 Methyl acetate Acetonitrile Methyl acrylate Methylparaben Kresoxim-methyl Paraquat dichloride 1,1'-Carbonyldiimidazole 1-(2,6-Dimethylphenoxy)-2-propanamine Methyl Methyl bromide Carbonyl iron powder NICKEL CARBONYL 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE Imidapril Diacid N-ISOPROPYL-AMINO-ACETIC ACID ETHYL ESTER HCL

(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid

IMIDAPRIL

(4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Aci

4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)-

4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, [4S-[3[R*(R*)],4R*]]-

(4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Acid Hydrochloride

(4S)-3-[(2S)-2-[N-[(1S)-1-(Ethyoxycarbonyl)-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid

lmidaprfil

(4S)-3-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid

(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid

(S,S,S)-Imidapril

Imidapril HCl

IMidapril (Tanatril)

Imidapril-d5 HCl

Imidapril USP/EP/BP

Imidapril Hyd

89371-37-9

9371-37-9

C20H27N3O6

Chiral Reagents

Intermediates & Fine Chemicals

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