PROTAC ERRα Degrader-1

Product Name: PROTAC ERRα Degrader-1
CAS No.: 2306388-84-9
Chemical Name: PROTAC ERRα Degrader-1
Synonyms: PROTAC ERRα Degrader-1;1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[2-[[(2E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-1-oxo-2-propen-1-yl]amino]ethyl]-2-oxo-
CBNumber: CB18054808
Molecular Formula: C54H49Cl2F6N7O8
Formula Weight: 1108.91
MOL File: 2306388-84-9.mol

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PROTAC ERRα Degrader-1 Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 11.80±0.46(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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PROTAC ERRα Degrader-1 Chemical Properties,Usage,Production

Description

ERRα Degrader-1 is a Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader.

Description

ERRα Degrader-1 is a Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader.

Uses

PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader[1].

IC 50

ERRα; MDM2

References

[1] Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772. DOI:10.1021/acsmedchemlett.9b00025

PROTAC ERRα Degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTAC ERRα Degrader-1 Suppliers

China 6 United States 1 Global 7

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
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Jilin Province Woda Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
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ShenZhen Trendseen Biological Technology Co.,Ltd.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Adooq Bioscience LLC

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PROTAC ERRα Degrader-1

1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[2-[[(2E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-1-oxo-2-propen-1-yl]amino]ethyl]-2-oxo-

2306388-84-9