PROTAC FLT-3 degrader 1

Product Name: PROTAC FLT-3 degrader 1
CAS No.: 2230826-81-8
Chemical Name: PROTAC FLT-3 degrader 1
Synonyms: FLT-3 degrader 1;PROTAC FLT-3 degrader 1;PROTACFLT-3degrader1/FLT3PROTAC;(2S,4R)-1-[(2S)-2-{3-[2-(2-{[4-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}phenyl)-7-thia-2,5-diazatricyclo[6.4.0.02,?]dodeca-1(8),3,5,9,11-pentaen-10-yl]oxy}ethoxy)ethoxy]propanamido}-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
CBNumber: CB95540575
Molecular Formula: C52H61N9O9S2
Formula Weight: 1020.23
MOL File: 2230826-81-8.mol

More

Less

PROTAC FLT-3 degrader 1 Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 150 mg/mL (147.03 mM; Need ultrasonic)
form: Solid
pka: 12.59±0.70(Predicted)
color: White to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0082105
Product name: PROTACFLT-3degrader1
Purity: 98.70%
Packaging: 1mg
Price: $780
Updated: 2021/12/16

ChemScene

Product number: CS-0082105
Product name: PROTACFLT-3degrader1
Purity: 98.70%
Packaging: 5mg
Price: $2000
Updated: 2021/12/16

ChemScene

Product number: CS-0082105
Product name: PROTACFLT-3degrader1
Purity: 98.70%
Packaging: 10mg
Price: $3200
Updated: 2021/12/16

More

Less

PROTAC FLT-3 degrader 1 Chemical Properties,Usage,Production

Biological Activity

PROTAC FLT-3 degrader 1 is a von Hippel-Lindau-based PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

References

[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.

PROTAC FLT-3 degrader 1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PROTAC FLT-3 degrader 1 Suppliers

China 16 United States 1 Global 17

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7777
Advantage: 56

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1636
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Wuhan Yuxiang Medical Technology Co., Ltd.

Tel: 13971275651
Email: sales@whyxpharma.com
Country: China
ProdList: 1836
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 9069
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 5001
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 36699
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: hanfangpharma@126.com; 18616537568
Email: hanfangpharma@126.com
Country: China
ProdList: 25801
Advantage: 58

2230826-81-8, PROTAC FLT-3 degrader 1Related Search:

PROTAC B-Raf degrader 1 PROTAC BRD9 Degrader-1 PROTAC ERRα Degrader-1 PROTAC K-Ras Degrader-1 PROTAC FAK degrader 1 PROTAC CRBN Degrader-1 Protein degrader 1 (TFA) PROTAC BET degrader-2 PROTAC RIPK degrader-2 PROTAC Bcl2 degrader-1 PROTAC 11 CDK9-PROTAC PROTAC ERRα Degrader-2 PROTAC FKBP Degrader-3 PROTAC CDK2/9 Degrader-1 GNE-987 PROTAC BRD4 Degrader-5 PROTAC ER Degrader-4

PROTAC FLT-3 degrader 1

PROTACFLT-3degrader1/FLT3PROTAC

FLT-3 degrader 1

(2S,4R)-1-[(2S)-2-{3-[2-(2-{[4-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}phenyl)-7-thia-2,5-diazatricyclo[6.4.0.02,?]dodeca-1(8),3,5,9,11-pentaen-10-yl]oxy}ethoxy)ethoxy]propanamido}-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide

2230826-81-8