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PROTAC BRD9 Degrader-1

Product Name
PROTAC BRD9 Degrader-1
CAS No.
2097971-01-0
Chemical Name
PROTAC BRD9 Degrader-1
Synonyms
PROTAC BRD9 Degrader-1;2-(4-{2-[N-(1,1-dioxo-1λ?-thian-4-yl)carbamimidoyl]-5-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridin-7-yl}-2-methoxyphenoxy)-N-[4-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamido)butyl]acetamide;Acetamide, N-[4-[[2-[4-[4,5-dihydro-2-[imino[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]methyl]-5-methyl-4-oxothieno[3,2-c]pyridin-7-yl]-2-methoxyphenoxy]acetyl]amino]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CBNumber
CB24845078
Molecular Formula
C42H45N7O12S2
Formula Weight
903.98
MOL File
2097971-01-0.mol
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PROTAC BRD9 Degrader-1 Property

Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 150 mg/mL (165.93 mM)
pka
10.68±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0028482
Product name
PROTACBRD9Degrader-1
Purity
99.37%
Packaging
5mg
Price
$900
Updated
2021/12/16
ChemScene
Product number
CS-0028482
Product name
PROTACBRD9Degrader-1
Purity
99.37%
Packaging
10mg
Price
$1500
Updated
2021/12/16
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PROTAC BRD9 Degrader-1 Chemical Properties,Usage,Production

Uses

PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology[1].

IC 50

BRD9: 13.5 nM (IC50); BRD4: 3.78 μM (IC50); CRBN-DDB1: 48.9 nM (IC50)

References

[1] Remillard D, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743. DOI:10.1002/anie.201611281

PROTAC BRD9 Degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTAC BRD9 Degrader-1 Suppliers

China 15 United States 2 Global 17
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1615
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054;
Email
trendseenbio@gmail.com
Country
China
ProdList
9069
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
China
ProdList
10024
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32034
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58

2097971-01-0, PROTAC BRD9 Degrader-1Related Search:

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  • PROTAC BRD9 Degrader-1
  • Acetamide, N-[4-[[2-[4-[4,5-dihydro-2-[imino[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]methyl]-5-methyl-4-oxothieno[3,2-c]pyridin-7-yl]-2-methoxyphenoxy]acetyl]amino]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
  • 2-(4-{2-[N-(1,1-dioxo-1λ?-thian-4-yl)carbamimidoyl]-5-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridin-7-yl}-2-methoxyphenoxy)-N-[4-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamido)butyl]acetamide
  • 2097971-01-0