PROTAC ER Degrader-3

Product Name: PROTAC ER Degrader-3
CAS No.: 2158322-29-1
Chemical Name: PROTAC ER Degrader-3
Synonyms: PROTAC ER Degrader-3;Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-...;Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-N-methyl-, 1,1-dimethylethyl ester
CBNumber: CB55419815
Molecular Formula: C71H77N7O12
Formula Weight: 1220.43
MOL File: 2158322-29-1.mol

More

Less

PROTAC ER Degrader-3 Property

Boiling point:: 1264.4±65.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.38±0.15(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

PROTAC ER Degrader-3 Chemical Properties,Usage,Production

Description

PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

References

[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

PROTAC ER Degrader-3 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PROTAC ER Degrader-3 Suppliers

China 4 United States 2 Global 6

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1456
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18478
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 9470
Advantage: 58

2158322-29-1, PROTAC ER Degrader-3Related Search:

PROTAC Bcl2 degrader-1 PROTAC BET degrader-2 PROTAC 11 PROTAC FLT-3 degrader 1 PROTAC CRBN Degrader-1 PROTAC B-Raf degrader 1 PROTAC BRD9 Degrader-1 PROTAC ERRα Degrader-1 PROTAC K-Ras Degrader-1 PROTAC FAK degrader 1 CDK9-PROTAC PROTAC ERRα Degrader-2 PROTAC FKBP Degrader-3 PROTAC CDK2/9 Degrader-1 GNE-987 PROTAC BRD4 Degrader-5 PROTAC ER Degrader-4 PROTAC IRAK4 degrader-1

PROTAC ER Degrader-3

Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-...

Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-N-methyl-, 1,1-dimethylethyl ester

2158322-29-1