GNE-987

Product Name: GNE-987
CAS No.: 2313234-00-1
Chemical Name: GNE-987
Synonyms: GNE-987;PROTAC BRD4 Degrader-3;(2S,4R)-1-[(2S)-2-(11-{[8-(3,5-difluoropyridin-2-yl)-4-(methanesulfonylmethyl)-15-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,?.013,1?]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-5-yl]formamido}undecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)phenoxy]pyrrolidine-2-carboxamide
CBNumber: CB95821290
Molecular Formula: C55H65F2N9O9S2
Formula Weight: 1098.29
MOL File: 2313234-00-1.mol

More

Less

GNE-987 Property

Density: 1.42±0.1 g/cm3(Predicted)
pka: 14.01±0.40(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

GNE-987 Chemical Properties,Usage,Production

Uses

PROTAC BRD4 Degrader-3 (compound 1004.1) is an efficacious PROTAC connected by ligands for von Hippel-Lindau and BRD4[1].

IC 50

BRD4

References

[1] Peter Dragovich, et al. (4-hydroxypyrrolidin-2-yl)-hydroxamate compounds and methods of use thereof. WO2019084030A1.

GNE-987 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GNE-987 Suppliers

China 8 United States 1 Global 9

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054;
Email: trendseenbio@gmail.com
Country: China
ProdList: 9069
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29496
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2772
Advantage: 58

2313234-00-1, GNE-987Related Search:

PROTAC B-Raf degrader 1 PROTAC BRD9 Degrader-1 PROTAC ERRα Degrader-1 PROTAC K-Ras Degrader-1 PROTAC FAK degrader 1 CDK9-PROTAC PROTAC ERRα Degrader-2 PROTAC FKBP Degrader-3 PROTAC Bcl2 degrader-1 PROTAC BET degrader-2 PROTAC 11 PROTAC CDK2/9 Degrader-1 PROTAC CRBN Degrader-1 PROTAC FLT-3 degrader 1 PROTAC IRAK4 degrader-1 PROTAC BRD4 Degrader-2 PROTAC BRD4 Degrader-5 PROTAC BRD4 Degrader-1

GNE-987

PROTAC BRD4 Degrader-3

(2S,4R)-1-[(2S)-2-(11-{[8-(3,5-difluoropyridin-2-yl)-4-(methanesulfonylmethyl)-15-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,?.013,1?]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-5-yl]formamido}undecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)phenoxy]pyrrolidine-2-carboxamide

2313234-00-1

C55H65F2N9O9S2