ChemicalBook > CAS DataBase List > PROTAC CRBN Degrader-1
PROTAC CRBN Degrader-1
- Product Name
- PROTAC CRBN Degrader-1
- CAS No.
- 2358775-70-7
- Chemical Name
- PROTAC CRBN Degrader-1
- Synonyms
- CRBN PROTAC?14a;PROTAC CRBN Degrader-1;N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide
- CBNumber
- CB88054807
- Molecular Formula
- C53H72N8O13S
- Formula Weight
- 1061.25
- MOL File
- Mol file
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PROTAC CRBN Degrader-1 Property
- Boiling point:
- 1241.2±65.0 °C(Predicted)
- Density
- 1.294±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 200 mg/mL (188.46 mM)
- pka
- 10.74±0.40(Predicted)
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PROTAC CRBN Degrader-1 Chemical Properties,Usage,Production
Description
CRBN PROTAC? 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation.
storage
Store at -20°C
PROTAC CRBN Degrader-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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