ChemicalBook > CAS DataBase List > Fumaryl chloride

Fumaryl chloride

Product Name
Fumaryl chloride
CAS No.
627-63-4
Chemical Name
Fumaryl chloride
Synonyms
tl189;TL 189;fumaryl;FumarylChoride;Fumarylchlorid;FUMARYL CHLORIDE;fumaroylchloride;Fumaroyl chloride;FUMARYL DICHLORIDE;chloruredefumaryle
CBNumber
CB1854022
Molecular Formula
C4H2Cl2O2
Formula Weight
152.96
MOL File
627-63-4.mol
More
Less

Fumaryl chloride Property

Melting point:
-2 °C
Boiling point:
161-164 °C(lit.)
Density 
1.415 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.499(lit.)
Flash point:
165 °F
storage temp. 
2-8°C
form 
Liquid
Specific Gravity
1.415 (20/4℃)
color 
Clear yellow
Water Solubility 
decomposes
Sensitive 
Moisture Sensitive
BRN 
1721342
InChIKey
ZLYYJUJDFKGVKB-OWOJBTEDSA-N
CAS DataBase Reference
627-63-4(CAS DataBase Reference)
NIST Chemistry Reference
Fumaryl chloride(627-63-4)
EPA Substance Registry System
2-Butenedioyl dichloride, (2E)- (627-63-4)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
20/21/22-34-37-29-36/37-14
Safety Statements 
26-36/37/39-45-8-27
RIDADR 
UN 1780 8/PG 2
WGK Germany 
3
RTECS 
LT2800000
21
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29171990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
151386
Product name
Fumaryl chloride
Purity
95%
Packaging
25g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
151386
Product name
Fumaryl chloride
Purity
95%
Packaging
5g
Price
$26
Updated
2022/05/15
TCI Chemical
Product number
F0152
Product name
Fumaryl Chloride
Purity
>95.0%(GC)(T)
Packaging
25g
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
F0152
Product name
Fumaryl Chloride
Purity
>95.0%(GC)(T)
Packaging
500g
Price
$387
Updated
2024/03/01
Alfa Aesar
Product number
A14540
Product name
Fumaryl chloride, 95%
Packaging
25g
Price
$45.65
Updated
2024/03/01
More
Less

Fumaryl chloride Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

Chemical intermediate for pharmaceuticals, dyestuffs, and insecticides.

Uses

Fumaryl chloride was used in the preparation of high molecular weight poly(propylene fumarate). The photodissociation dynamics of fumaryl chloride was studied. It is used in agrochemicals and pharmaceuticals manufacturing. Also used as an intermediate for dyes, textile auxiliaries and peroxide compounds. It is an acid halide building block.

Preparation

Fumaryl chloride has been prepared from fumaric acid and phthaloyl chloride, from maleic acid by the action of thionyl chloride in the presence of zinc chloride, and from maleic anhydride by the use of phthaloyl chloride in the presence of zinc chloride.
Org. Synth. 1940, 20, 51
DOI: 10.15227/orgsyn.020.0051

General Description

Fumaryl chloride appears as a straw colored fuming liquid with a pungent odor. Vapors irritate the eyes and mucous membranes. Corrosive to metals and tissue.

Reactivity Profile

Fumaryl chloride is incompatible with strong oxidizing agents, alcohols, amines and other bases. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Corrosive to eyes and skin.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Moderately toxic by ingestion, inhalation, and skin contact. A skin, eye, and mucous membrane irritant. A corrosive agent. Will react with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of phosgene and HCl.

Fumaryl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Fumaryl chloride Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653715
Email
xingui2022@126.com
Country
China
ProdList
10015
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5113
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL:0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6116
Advantage
58
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ:2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6501
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-(0)57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29793
Advantage
60
Foshan DaoQi Biological Co., Ltd.
Tel
18062666947
Fax
18062666959
Email
2355880548@qq.com
Country
China
ProdList
4228
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Rionlon ( Tianjin ) Industry Co.,Ltd.
Tel
13512289226
Email
yangli@rionlon.com
Country
China
ProdList
37
Advantage
58
Rionlon ( Tianjin ) Pharmaceutical Co., Ltd.
Tel
0086-13512289226
Email
yangli@rionlon.com
Country
CHINA
ProdList
28
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29810
Advantage
58
Yikang Chemical(Hubei)Co., LTD
Tel
027-18971353-902 18971353902
Email
2242508613@qq.com
Country
China
ProdList
7867
Advantage
58
Antai Fine Chemical Technology Co.,Limited
Tel
18503026267
Email
info@antaichem.com
Country
CHINA
ProdList
9636
Advantage
58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com
Country
China
ProdList
5738
Advantage
58
DONBOO AMINO ACID COMPANY
Tel
+8613063595538
Email
donboo@donboo.com
Country
China
ProdList
9363
Advantage
58
Quzhou mingfeng chemical co., ltd
Tel
0570-3062502 13819002126
Fax
0570-3063388
Email
41774453@qq.com
Country
China
ProdList
4357
Advantage
58
Shandong Tianming Biotechnology Development Co. Ltd
Tel
400-9019001
Country
China
ProdList
15069
Advantage
58
WUHAN JIXINYIBANG BIOTECHNOLOGY .,LTD
Tel
027-59768661 13297943853
Email
1704244976@qq.com
Country
China
ProdList
4992
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
10006
Advantage
58
Jiangsu Pules Bio-tech Co.,Ltd
Tel
0513-66017706 18551496367
Email
2186883463@qq.com
Country
China
ProdList
4727
Advantage
58
Pand (Shanghai) international trade Co., LTD
Tel
18662931292 18662931292
Email
3404730042@qq.com
Country
China
ProdList
4854
Advantage
58
Shanghai Hongboshangyi Pharmaceutical Technology Co. , Ltd.
Tel
021-58999902
Email
huangjiahui@prssh.com
Country
China
ProdList
2311
Advantage
58
Hangzhou Bingochem Co., Ltd.
Tel
0571-8512-5372
Email
sales@bingochem.com
Country
China
ProdList
21669
Advantage
58
JIANGSU BSECHEM CHEMICAL TECHNOLOGY Co., Ltd
Tel
15651337098
Email
15651337098@163.com
Country
China
ProdList
4429
Advantage
58
Jiangsu Raien Environmental Protection Technology Co., Ltd
Tel
0513-0513-66814573 16651336298
Email
16651336298@163.com
Country
China
ProdList
4210
Advantage
58
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Tel
18117346937 18117346937
Email
18117346937@163.com
Country
China
ProdList
4713
Advantage
58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
Tel
+8618950047208
Email
ellena@amitychem.com
Country
China
ProdList
19684
Advantage
58
More
Less

View Lastest Price from Fumaryl chloride manufacturers

Career Henan Chemical Co
Product
Fumaryl chloride 627-63-4
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

627-63-4, Fumaryl chlorideRelated Search:


  • Dichlorid kyseliny fumarove
  • trans-Butenedioyl chloride
  • FUMAROYL DICHLORIDE
  • FUMARYL CHLORIDE
  • FUMARYL DICHLORIDE
  • trans-2-Butenedioyl dichloride
  • Fumarylchloride,95%
  • FumarylChoride
  • 2-Butenedioyl dichloride, (2E)-
  • 2-Butenedioyl dichloride
  • (E)-2-Butenedioyl dichloride
  • (E)-2-Butenedioic acid dichloride
  • Fumaric acid dichloride
  • FuMaryl chloride, 95% 25ML
  • FUMARYL CHLORIDE FOR SYNTHESIS
  • trans-butenedioyl dichloride
  • (2E)-2-Butenedioyl dichloride
  • (E)-1,4-Dioxo-2-butenyldichloride
  • (e)-2-butenedioyldichlorid
  • (E)-butenedioyldichloride
  • 2-Butenedioyl dichloride, (E)-
  • Chlorure de fumaryle
  • chloruredefumaryle
  • dichloridkyselinyfumarove
  • Fumaroyl chloride
  • fumaroylchloride
  • fumaryl
  • Fumarylchlorid
  • TL 189
  • tl189
  • FumarylChloride&gt
  • (E)-But-2-enedioyl dichloride
  • 627-63-4
  • C4H2Cl2O2
  • CHCOC12
  • ClCOCHCHCOCl
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Building Blocks
  • Carbonyl Compounds
  • Organic Building Blocks
  • Acid Halides
  • FM - FZ
  • Alphabetic
  • Acid Halides
  • Carbonyl Compounds
  • Organic Building Blocks