9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

Product Name: 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
CAS No.: 206184-49-8
Chemical Name: 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
Synonyms: Tenofovir CRS;Tenofovir(H2O);Unii-99yxe507il;PMPA Monohydrate;Tenofovir (15 mg);Tenofovir (hydrate);R-PMPA of Tenofovir;Tenofovir (1643601);Tenofovir Monohydrate;Tenofovir hydrate (1:1)
CBNumber: CB1855342
Molecular Formula: C9H16N5O5P
Formula Weight: 305.23
MOL File: 206184-49-8.mol

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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Property

Melting point:: 270-274oC
storage temp.: 2-8°C
solubility: Aqueous Acid (Slightly), DMSO (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Safety

HS Code: 2933599550

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1592
Product name: Tenofovir
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 1G
Price: $160
Updated: 2022/05/15

Sigma-Aldrich

Product number: 1643601
Product name: Tenofovir
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15MG
Price: $400
Updated: 2022/05/15

TRC

Product number: T185533
Product name: TenofovirMonohydrate
Packaging: 2.5g
Price: $145
Updated: 2021/12/16

ChemScene

Product number: CS-1874
Product name: Tenofovir Hydrate
Purity: ≥98.0%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ApexBio Technology

Product number: B1252
Product name: Tenofovir Hydrate
Packaging: 50mg
Price: $221
Updated: 2021/12/16

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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Chemical Properties,Usage,Production

Chemical Properties

WHITE POWDER SOLID

Uses

Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.

Uses

antineoplastic, thymidylate synthase inhibitor

Definition

ChEBI: A hydrate that is the monohydrate form of anhydrous tenovir.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tenofovir is a nucleotide analog reverse transcriptase inhibitor, and is widely used as an antiretroviral agent, for the treatment of HIV infection.

Biological Activity

tenofovir hydrate is an inhibitor of reverse transcriptase used for the treatment of the human immunodeficiency virus 1(hiv-1) and hepatitis b [1].tenofovir hydrate is an antiviral pro-drug and the class of nucleoside reverse transcriptase inhibitor. in addition, tenofovir hydrate has been reported to have a dependent relation between intracellular the drug concentrations and prevent function of hiv-1infection with ec50 values of 29 fmol/106, 40 fmol/106 , 77 fmol/106 and 411 fmol/106 cells for inoculum size 1, 5, 20 and 100 respectively. and the ec90 values of tenofovir hydrate are 267 fmol/106, 348 fmol/106, 640 fmol/106 and 2866 fmol/106 cells for virus inoculums size 1, 5, 20 and 100, respectively [1].

References

[1] duwal s1, schütte c, von kleist m.pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against hiv-1 infection. plos one. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. epub 2012 jul 11.

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Suppliers

China 132 India 8 United Kingdom 1 United States 18 Global 159

Huangshi Fuertai Pharmaceutical Tech Co., Ltd.

Tel: 0714-3293168-6021 13995956430
Fax: 0714-6392351
Email: fuertaixia@foxmail.com
Country: China
ProdList: 38
Advantage: 58

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
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MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
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HBCChem, Inc.

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Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
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Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9346
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Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
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Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10276
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View Lastest Price from 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate manufacturers

Hangzhou ICH Biofarm Co., Ltd

Product: 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98% HPLC
Supply Ability: 100kg
Release date: 2023-07-12

Career Henan Chemical Co

Product: 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

206184-49-8, 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrateRelated Search:

N-(n-Butyl)thiophosphoric triamide Hexamethylphosphoramide Glycine OLEYLOXYETHYL PHOSPHORYLCHOLINE Bucladesine MELIBIOSE Adenine Bensulfuron methyl Trimethyl phosphite Propyl gallate Thiophanate-methyl Kresoxim-methyl Methylparaben Choline glycerophosphate 6-Aminocaproic acid Propyl butyrate Dibutyryl adenosine cyclophosphate calcium Tenofovir disoproxil fumarate

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

Unii-99yxe507il

Tenofovir Monohydrate

Tenofovir (15 mg)

Tenofovir (hydrate)

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate

PMPA Monohydrate

(R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid hydrate

(r)-[[2-(6-amino-9h-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid monohydrate

[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methylphosphonic acid

(R)-9-(2-phosphonylmethoxy propyl)adenine(R-PMPA)

R-PMPA of Tenofovir

Tenofovir(H2O)

Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1)

9-[(R)-2-(Phosphonomethoxy)propyl]adenine 1-hydrate

P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Hydrate

Tenofovir hydrate (GS 1278)

Tenofovir (1643601)

({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid hydrate

Tenofovir CRS

Tenofovir hydrate (1:1)

9-[(R)-2-(Phosphonomethoxy)propyl] adenine monohydrate [PMPA]

206184-49-8

C9H14N5O4PH2O

C9H16N5O5P

ALIMTA