6-Bromoindole-3-carboxaldehyde
- Product Name
- 6-Bromoindole-3-carboxaldehyde
- CAS No.
- 17826-04-9
- Chemical Name
- 6-Bromoindole-3-carboxaldehyde
- Synonyms
- 6-BROMO-3-FORMYLINDOLE;6-broMo-3-carboxaldehyde;6-BROMO-3-FORMYL-1H-INDOLE;6-BROMOINDOLE-3-CARBOXALDEHYDE;6-BROMO-1H-INDOLE-3-CARBALDEHYDE;6-BROMO-1H-INDOLE-3-CARBOXALDEHYDE;6-Bromoindole-3-carboxaldehyde >1H-Indole-3-carboxaldehyde, 6-bromo-;6-Aminoindole-3-carboxaldehyde Factory;6-Bromo-1H-indole-3-carbaldehyde, 6-Bromo-3-formylindole
- CBNumber
- CB2100063
- Molecular Formula
- C9H6BrNO
- Formula Weight
- 224.05
- MOL File
- 17826-04-9.mol
6-Bromoindole-3-carboxaldehyde Property
- Melting point:
- 202-206 °C
- Boiling point:
- 395.6±22.0 °C(Predicted)
- Density
- 1.727±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Solid
- pka
- 14.57±0.30(Predicted)
- color
- Light yellow to Brown
- CAS DataBase Reference
- 17826-04-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36-36/37/39-22
- RIDADR
- UN2811
- WGK Germany
- 3
- Hazard Note
- Harmful
- HazardClass
- 6.1
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 666416
- Product name
- 6-Bromoindole-3-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $52.2
- Updated
- 2023/06/20
- Product number
- 666416
- Product name
- 6-Bromoindole-3-carboxaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $212
- Updated
- 2023/06/20
- Product number
- B2778
- Product name
- 6-Bromoindole-3-carboxaldehyde
- Purity
- >98.0%(GC)(N)
- Packaging
- 1g
- Price
- $74
- Updated
- 2025/07/31
- Product number
- B2778
- Product name
- 6-Bromoindole-3-carboxaldehyde
- Purity
- >98.0%(GC)(N)
- Packaging
- 5g
- Price
- $251
- Updated
- 2025/07/31
- Product number
- B686563
- Product name
- 6-Bromo-1H-indole-3-carbaldehyde
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
6-Bromoindole-3-carboxaldehyde Chemical Properties,Usage,Production
Uses
6-Bromoindole-3-carboxaldehyde, also known as 6-Bromo-1H-indole-3-carbaldehyde, is a halogenated reagent used in the synthesis of indoles and their derivatives. It is also a biochemical reagent used in life science related research.
Definition
6-bromoindole-3-carboxaldehyde is a member of indoles.
Application
6-Bromo-1H-indole-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
52415-29-9
68-12-2
17826-04-9
6-Bromo-1H-indole-3-carbaldehyde was synthesized as follows: 1) N,N-dimethylformamide (10 mL) was cooled to 0 °C under nitrogen protection and phosphorus trichloride (3.2 mL, 34.6 mmol) was slowly added keeping the reaction temperature between 0 °C and 80 °C. The reaction was carried out by stirring the reaction mixture for 30 min. 2) Stir the reaction mixture at 0 °C for 30 min. 3) Slowly add a solution of N,N-dimethylformamide (28 mL) of 6-bromoindole (5.5 g, 28.1 mmol), keeping the reaction temperature between 0 °C and 10 °C. 4) The ice water bath was removed and the reaction mixture was stirred at room temperature for 2 hours. 5) The viscous reaction mixture was poured into ice water (250 g) and the pH was adjusted to about 7 with 1N sodium hydroxide solution (tested using litmus paper). 6) The mixture was allowed to stand at room temperature overnight. 7) The pink solid was collected by filtration, washed with water, and recrystallized from ethanol to give 6-bromo-1H-indole-3-carbaldehyde (1.6 g, 25% yield) as a light tan solid. 1H NMR (d6-DMSO, 400 MHz): δ 12.20 (br s, 1H), 9.91 (s, 1H), 8.31 (d, J = 3 Hz, 1H), 8.00 (d, J = 9 Hz, 1H), 7.69 (d, J = 2 Hz, 1H), 7.34 (dd, J = 8, 2 Hz, 1H).
References
[1] European Journal of Organic Chemistry, 2016, vol. 2016, # 27, p. 4621 - 4628
[2] Chinese Chemical Letters, 2010, vol. 21, # 8, p. 889 - 891
[3] Marine Drugs, 2013, vol. 11, # 5, p. 1427 - 1439
[4] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 344 - 367
[5] Angewandte Chemie - International Edition, 2014, vol. 53, # 22, p. 5600 - 5603
6-Bromoindole-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Bromoindole-3-carboxaldehyde manufacturers
- Product
- 6-Bromoindole-3-carboxaldehyde 17826-04-9
- Price
- US $9.85/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 m
- Release date
- 2024-11-29
- Product
- 6-Aminoindole-3-carboxaldehyde Factory 17826-04-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 largest production capacity Factory
- Release date
- 2019-04-03
- Product
- 6-Bromoindole-3-carboxaldehyde 17826-04-9
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- 99%
- Supply Ability
- G/KG/T
- Release date
- 2019-12-20