Patchouli oil
Chemical constituents pharmacology- Product Name
- Patchouli oil
- CAS No.
- 8014-09-3
- Chemical Name
- Patchouli oil
- Synonyms
- PATCHOULI;FEMA 2838;PATCHOULY OIL;Patchouli oil;OIL, PATCHOULY;Oils,patchouli;UNII-F3IN55X5PO;OIL OF PATCHOULY;OIL OF PATCHOULI;patchouli absolute
- CBNumber
- CB2130860
- Formula Weight
- 0
- MOL File
- Mol file
Patchouli oil Property
- Boiling point:
- 287 °C(lit.)
- Density
- 0.963 g/mL at 25 °C(lit.)
- FEMA
- 2838 | PATCHOULY OIL
- refractive index
- n20/D 1.509(lit.)
- Flash point:
- 230 °F
- Odor
- at 100.00 %. sweet herbal spicy woody fruity
- Odor Type
- woody
- CAS DataBase Reference
- 8014-09-3
- EPA Substance Registry System
- Oils, patchouli (8014-09-3)
Safety
- WGK Germany
- 3
- RTECS
- RW7126400
- Toxicity
- LD50 orl-rat: >5 g/kg FCTOD7 20,791,82
N-Bromosuccinimide Price
- Product number
- 34775
- Product name
- Patchoulioil100%Pure,Natural,meetsFGspecifications,Kosher,FEMA2
- Packaging
- 5KG
- Price
- $896.9
- Updated
- 2021/12/16
- Product number
- 34775
- Product name
- Patchoulioil100%Pure,Natural,meetsFGspecifications,Kosher,FEMA2
- Packaging
- 25KG
- Price
- $3669.12
- Updated
- 2021/12/16
Patchouli oil Chemical Properties,Usage,Production
Chemical constituents
Three terpenoids Germacrene, Patchoulol or patchouli alcohol, Norpatchoulenol found in patchouli oil are responsible for the typical patchouli scent. TLC and HPLC were used to identify the possible chemical markers for evaluating the quality of the crude drug "Pogostemoni herba" (aerial part of P. cablin), a component of Kampo medicines. In addition to the reported patchouli alcohol and 2-hydroxy-6-methyl-3-(4-methylpentanoyl)-4-pyrone, three phenylethanoids (acteoside, isoacteoside, and crenatoside) were isolated from this plant material for the first time.
pharmacology
Antimicrobial Activity
Patchouli alcohol, a major component in patchouli oil, and the extract showed higher antibacterial activity than the mixture of β-sitosterol and stigmasterol and 7,3′,4-tri-O-methyleriodictyol.54 The essential oil of P. cablin showed antibacterial activity against periodontopathic bacteria, including Actinobacillus, Capnocytophaga, Fusobacterium, Eikenella.
Antiviral activity
The anti-influenza A (H2N2) virus activity of patchouli alcohol was studied in vitro, in vivo and in silico. The CC (50) of patchouli alcohol was above 20 μM. It could inhibit influenza virus with an IC (50) of 4.03 ± 0.23 μM.
Other Activities
Patchouli oil main constituent, patchouli alcohol was found to be toxic and repellent against Formosan subterranean termites.
Chemical Properties
Patchouli oil is produced by steam distillation of the dried leaves of Pogostemon cablin (Blanco) Benth. (Lamiaceae). It is a reddish-brown to greenish-brown, more or less viscous liquid with a characteristic, slightly camphoraceous, woody balsamic odor.
d2020 0.952–0.975; n20D 1.5050–1.5150; α20D ?60 ° to ?40 °; solubility: 1 vol in not more than 10 vol of 90% ethanol at 20 °C; acid number:max. 4; ester number:max. 10.
The patchouli shrub is cultivated primarily in Indonesia. It grows to 1m, but during harvesting, it is cut back to 10–15 cm. The oil yield from preferably sundried leaves is about 2%.
Although the sesquiterpene alcohol (?)-patchoulol is the main component of patchouli oil (27–35%), this compound contributes less to the characteristic odor of the oil than (+)-norpatchoulenol present only at a concentration of 0.35–1%. Other typical constituents are (+)-α-bulnesene (13–21%), (?)-α-guaiene (11–16%), (?)-β-patchoulene (1.8–3.5%), and (?)-seychellene(1–3%).
Chemical Properties
The oil is obtained by steam distillation of properly dried leaves in approximately 1.5 to 3.0% yields. The oil has a typical camphoraceous odor and woody undernote imparted sometimes by adulteration of the oil with gurjum balsam. The classic patchouly odor is recognizable in the high-quality oil manufactured in the Malaysian state of Johore and marketed under the name of Paxamo Special Singapore.
Physical properties
Independent of its origin, the essential oil is a slightly viscous, brown liquid.
Uses
The botanical properties of patchouli oil (Pogostemon patchouli)(patchouly) are described as astringent, anti-inflammatory, decongestive, and tonic. It can be stimulant in low doses, and sedative at high doses. Its botanical attributes make it useful for acne, aged and chapped skin, and skin redness. In Asia, it was a renowned antidote against insect and snake bites. Also used as a perfume in soaps and cosmetics to impart a long-lasting aroma. This oil has a strong, sweet, musty, and very persistent fragrance. The patchouli leaves are dried and fermented prior to distilla tion. It may produce an allergic reaction in sensitive individuals.
Definition
Extractives and their physically modified derivatives. Pogostemon cablin (Pogostemon patchouli), Labiatae.
Essential oil composition
The main known constituents include benzaldehyde, eugenol, cinnamaldehyde, patchouly alcohol (a tricyclic alcohol, C15H260), two hydrocarbons (C15H24), and other minor unidentified components (Burdock, 1997).
Safety Profile
Low toxicity by ingestion and skin contact. A skin irritant. A combustible liquid. When heated to decompositionit emits acrid smoke and irritating vapors.
Patchouli oil Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Patchouli oil manufacturers
- Product
- Patchouli oil 8014-09-3
- Price
- US $0.01-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-04-20
- Product
- Patchouli Oil;Patchouli Essential Oil 8014-09-3
- Price
- US $22.00-18.00/KG
- Min. Order
- 1KG
- Purity
- 100% Pure Natural
- Supply Ability
- 2000KGs
- Release date
- 2022-01-13
- Product
- Patchouli oil 8014-09-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 500000kg
- Release date
- 2023-05-26