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PANCREATIC POLYPEPTIDE (BOVINE)

Product Name
PANCREATIC POLYPEPTIDE (BOVINE)
CAS No.
179986-89-1
Chemical Name
PANCREATIC POLYPEPTIDE (BOVINE)
Synonyms
PANCREATIC POLYPEPTIDE (BOVINE);Pancreatic polypeptide (pig),6-L-glutamic acid-;H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
CBNumber
CB2160531
Formula Weight
0
MOL File
Mol file
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PANCREATIC POLYPEPTIDE (BOVINE) Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0044801
Product name
PancreaticPolypeptide,bovine
Packaging
500ug
Price
$210
Updated
2021/12/16
ChemScene
Product number
CS-0044801
Product name
PancreaticPolypeptide,bovine
Packaging
1mg
Price
$330
Updated
2021/12/16
ChemScene
Product number
CS-0044801
Product name
PancreaticPolypeptide,bovine
Packaging
5mg
Price
$1100
Updated
2021/12/16
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PANCREATIC POLYPEPTIDE (BOVINE) Chemical Properties,Usage,Production

Biological Activity

Pancreatic Polypeptide, bovine is a linear polypeptide of 36 amino acids produced in the pancreas that inhibits pancreatic secretion induced by secretin and cholecystokinin. It is a neuropeptide (NPY) receptor agonist with high affinity for NPYR4.

in vitro

Pancreatic Polypeptide, bovine is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic Polypeptide (1 μM) does not alter proliferation in BRIN BD11 or 1.1B4 beta-cells, but reverses the decreased cell viability in BRIN BD11 cells induced by streptozotocin. Pancreatic Polypeptide (0.1 nM-1 μM) shows no effect on insulin secretion from isolated mouse islets, and does not affect the membrane potential and (Ca 2+ ) i levels in BRIN BD11 cells at 1 μM. Pancreatic Polypeptide, bovine inhibits secretin- and cholecystokinin-stimulated pancreatic secretion. 125 I-Pancreatic Polypeptide, bovine shows no specific binding to pancreatic acini.

in vivo

Pancreatic Polypeptide (25 nmol/kg bw, ip) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice. Pancreatic Polypeptide, bovine (BPP; 40 μg/kg) inhibits CCK -33-induced pancreatic protein output during the entire bovine Pancreatic Polypeptide infusion period, but shows no effect on biliary protein output during CCK-33 or CCK-8 infusion.

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PANCREATIC POLYPEPTIDE (BOVINE) Preparation Products And Raw materials

Raw materials

Preparation Products

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PANCREATIC POLYPEPTIDE (BOVINE) Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
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60
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
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55
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9980
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Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4814
Advantage
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Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6968
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
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58

179986-89-1, PANCREATIC POLYPEPTIDE (BOVINE)Related Search:


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