PROCYANIDIN B3
- Product Name
- PROCYANIDIN B3
- CAS No.
- 23567-23-9
- Chemical Name
- PROCYANIDIN B3
- Synonyms
- RS533;RS 533;RS-533;PROCYANIDIN B3;Procyanidol B3;PROCYANIDIN B3 USP/EP/BP;procyanidin B3 from barley;CATECHIN-(4ALPHA->8)-CATECHIN;Procyanidin B3, 10 mM in DMSO;CATECHIN-(4ALPHA->8)-CATECHIN B3
- CBNumber
- CB2172174
- Molecular Formula
- C30H26O12
- Formula Weight
- 578.52
- MOL File
- 23567-23-9.mol
PROCYANIDIN B3 Property
- Melting point:
- 218-219℃
- Boiling point:
- 955.3±65.0 °C(Predicted)
- Density
- 1.705
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in acetone and acetonitrile
- form
- powder
- pka
- 9.29±0.60(Predicted)
- color
- White
- InChIKey
- XFZJEEAOWLFHDH-AVFWISQGSA-N
- SMILES
- [C@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2[C@@H](C2=C3O[C@H](C4=CC=C(O)C(O)=C4)[C@@H](O)CC3=C(O)C=C2O)[C@@H]1O
- CAS DataBase Reference
- 23567-23-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 29065
- Product name
- Procyanidin B3
- Packaging
- 1mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 29065
- Product name
- Procyanidin B3
- Packaging
- 10mg
- Price
- $330
- Updated
- 2024/03/01
- Product number
- 29065
- Product name
- Procyanidin B3
- Packaging
- 5mg
- Price
- $180
- Updated
- 2024/03/01
- Product number
- 361861
- Product name
- Procyanidin B3
- Packaging
- 5mg
- Price
- $765
- Updated
- 2021/12/16
- Product number
- FP65542
- Product name
- Procyanidin B3
- Packaging
- 100ug
- Price
- $50
- Updated
- 2021/12/16
PROCYANIDIN B3 Chemical Properties,Usage,Production
Uses
Procyanidin B3 is a natural product that acts as a specific HAT inhibitor. Procyanidin B3 is a polyphenol flavonoid dimer of (+)-catechin with diverse biological properties. Procyanidin B3 is a dimeric flavanol and an antifungal phenol extracted from Woodfordia uniflora.
Definition
ChEBI: A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarp Macho.
in vivo
Procyanidin B3 (100 mg/kg, p.o., 5 days a week for 4 weeks) prevents articular cartilage degeneration and heterotopic cartilage formation in a surgically-induced osteoarthritis mice model[2]. Procyanidin B3 (30 mg/kg, p.o., once daily for 4 weeks) delays the development of intervertebral disc degeneration (IVDD) in a Lipopolysaccharides (HY-D1056)-induced IVDD Sprague-Dawley rats model[2].
| Animal Model: | Lipopolysaccharides (HY-D1056)-induced IVDD (intervertebral disc degeneration) Sprague-Dawley rats model |
| Dosage: | 30 mg/kg |
| Administration: | Oral gavage (p.o.),once daily for 4 weeks |
| Result: | Prevented the loss of gelatin NP cells and structural damage of annulus fibrosus in IVDD rat model. |
| Animal Model: | Surgically-induced osteoarthritis mice model[2] |
| Dosage: | 100 mg/kg |
| Administration: | Oral gavage (p.o.), once daily, 5 days a week for 4 weeks |
| Result: | Prevented aberrant articular cartilage degeneration and heterotopic cartilage formation through suppression of the nitric oxide synthase (iNOS). |
IC 50
CBP/p300; TLR4
PROCYANIDIN B3 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PROCYANIDIN B3 manufacturers
- Product
- Procyanidin B3 23567-23-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-28
- Product
- Procyanidin B3 23567-23-9
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 100kg
- Release date
- 2019-12-23