ChemicalBook > CAS DataBase List > Porcine Insulin

Porcine Insulin

Product Name
Porcine Insulin
CAS No.
12584-58-6
Chemical Name
Porcine Insulin
Synonyms
INSULIN;Pig Insulin;insulin(pig);insulin(dog);porcineinsulin;neutralinsulin;insulinprocine;Insulin (Pork);insulin,neutral;Insulin (swine)
CBNumber
CB2176233
Molecular Formula
C256H381N65O76S6
Formula Weight
5777.54
MOL File
Mol file
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Porcine Insulin Property

storage temp. 
-20°C
solubility 
It can be solubilized in dilute acetic or hydrochloric acid, pH 2-3.
form 
powder
color 
White to Off-White
Merck 
13,5003
Stability:
Hygroscopic
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NM8895000
10
HS Code 
2937120000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I5523
Product name
Insulin from porcine pancreas
Packaging
10mg
Price
$174
Updated
2024/03/01
Sigma-Aldrich
Product number
1342300
Product name
Insulin (Pork)
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$459
Updated
2024/03/01
Alfa Aesar
Product number
J61321
Product name
Insulin, from porcine pancreas, 97%
Packaging
250mg
Price
$628
Updated
2021/12/16
Alfa Aesar
Product number
J61321
Product name
Insulin, from porcine pancreas, 97%
Packaging
25mg
Price
$234
Updated
2021/12/16
Sigma-Aldrich
Product number
Y0001717
Product name
Insulin porcine for system suitability
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001717
Price
$220
Updated
2024/03/01
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Porcine Insulin Chemical Properties,Usage,Production

Description

Porcine Insulin is a double-chain protein with a molecular mass of 5778, containing 51 amino acids (A-21 and B-30 chains) connected by a disulfide bond. Porcine Insulin has a high degree of similarity to human insulin, differing only in the 30th amino acid. porcine Insulin regulates the uptake, utilisation and storage of glucose, amino acids and fatty acids in cells and inhibits the breakdown of glycogen, proteins and lipids. Therefore, it is used to control hyperglycaemia in diabetic patients.

Chemical Properties

White or almost white powder

Uses

Insulin, from porcine pancreas, is used in the determination of the beta-cell reserve during glucose tolerance test or after a carbohydrate rich meal, as a guide for the instauration of insulin therapy, contribution to the diagnosis of insulin and non-insulin-dependent diabetes, characterisation and follow-up of states of glucose intolerance, diagnosis and study of cases of insulin resistance, diagnosis of insulinoma and other causes of hypoglycemia.

Uses

Hormone; treatment of diabetes mellitus.

Biological Functions

Insulin has anabolic properties that include the stimulation of both skeletal muscle and liver cells to incorporate glucose and convert it to glycogen, to synthesize proteins from amino acids in the blood, and to act on fat cells to enhance their uptake of glucose and the synthesis of fat. In short, insulin encourages anabolism rather than catabolism, because it promotes the synthesis of glycogen, proteins, and lipids. A deficiency of insulin, which characterizes the disease diabetes mellitus (DM), causes extreme changes in the entire metabolic pattern of individuals with DM. Patients with DM often demonstrate elevated blood glucose levels, excess glucose in the urine, and failure to properly utilize carbohydrate and lipids.

Biochem/physiol Actions

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Porcine Insulin Preparation Products And Raw materials

Raw materials

Preparation Products

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Porcine Insulin Suppliers

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View Lastest Price from Porcine Insulin manufacturers

Hebei Jiafan Trading Company Limited
Product
Insulin 12584-58-6
Price
US $5.00/Box
Min. Order
1Box
Purity
99.99%
Supply Ability
20000 boxes
Release date
2024-12-20
Shandong Huizhihan Supply Chain Co., Ltd
Product
Insulin 12584-58-6
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99.99%
Supply Ability
1000
Release date
2024-10-30
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Insulin 12584-58-6
Price
US $200.00-95.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000 Pieces Per Year
Release date
2024-05-09

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