Vanillyl ethyl ether

Product Name: Vanillyl ethyl ether
CAS No.: 13184-86-6
Chemical Name: Vanillyl ethyl ether
Synonyms: FEMA 3815;DAIRY ENHANCER;VanilinEthylEther;ETHYL VANILLYL ETHER;VANILLYL ETHYL ETHER;Vanilla alcohol ether;Xianglan alcohol ether;13184-86-6 Vanillyl ethyl ether;4-[ETHOXYMETHYL]-2-METHOXYPHENOL;Phenol, 4-(ethoxymethyl)-2-methoxy-
CBNumber: CB2183240
Molecular Formula: C10H14O3
Formula Weight: 182.22
MOL File: 13184-86-6.mol

More

Less

Vanillyl ethyl ether Property

Boiling point:: 125°C/4mmHg(lit.)
Density: 1.087±0.06 g/cm3(Predicted)
refractive index: 1.5280 to 1.5320
FEMA: 3815 | VANILLYL ETHYL ETHER
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
pka: 9.73±0.20(Predicted)
color: Colorless to Almost colorless
Odor: at 20.00 % in ethyl alcohol. alcoholic rum sweet chocolate creamy vanilla spicy nutmeg smoky
Odor Type: chocolate
JECFA Number: 887
LogP: 1.46
CAS DataBase Reference: 13184-86-6
NIST Chemistry Reference: Phenol, 4-(ethoxymethyl)-2-methoxy-(13184-86-6)
EPA Substance Registry System: Phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)

More

Less

Safety

HS Code: 2909500090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: E1028
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: >98.0%(GC)
Packaging: 5g
Price: $98
Updated: 2025/07/31

AK Scientific

Product number: J96485
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Packaging: 5g
Price: $30
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: FFG0000629
Product name: VANILLYL ETHYL ETHER
Purity: 98.00%
Packaging: 5MG
Price: $503.05
Updated: 2021/12/16

Ambeed

Product number: A198590
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: 97%
Packaging: 1g
Price: $11
Updated: 2021/12/16

Ambeed

Product number: A198590
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: 97%
Packaging: 5g
Price: $30
Updated: 2021/12/16

More

Less

Vanillyl ethyl ether Chemical Properties,Usage,Production

Chemical Properties

Vanillyl ethyl ether has a phenolic, smoky odor and a strong, pungent taste.

Occurrence

Reportedly present in grape brandy (cognac), rum, whiskey and vanilla.

Uses

flavors and fragrances

Definition

ChEBI: 4-(Ethoxymethyl)-2-methoxyphenol is a member of phenols and a member of methoxybenzenes.

Preparation

In a patented process, prepared by the reaction of cyclodextrin or branched-cyclodextrin with vanillyl alcohol.

Synthesis

121-33-5

122-51-0

13184-86-6

General procedure for the synthesis of vanillyl ethyl ether from vanillin and triethyl orthoformate: 3.04 g (20.0 mmol) of vanillin, 5.93 g (40.0 mmol) of triethyl orthoformate, 15.0 mg of p-toluenesulphonic acid monohydrate, and 15.0 mg 5% palladium-carbon catalyst were added to a 100 ml autoclave (equipped with an inner tube). After displacing the internal gas of the system under nitrogen protection, it was replaced with hydrogen and filled with hydrogen at 3.0 MPa. The autoclave temperature was controlled at 130°C and the reaction was continuously stirred for 1 hour. Upon completion of the reaction, the reaction mixture was cooled and the hydrogen pressure was subsequently released. The palladium carbon catalyst was removed by filtration and the unreacted triethyl orthoformate was recovered by distillation under reduced pressure, resulting in 3.60 g of vanillyl ethyl ether (97.4% purity and 96.2% yield as determined by internal standard method). The structure of the product was confirmed by 1H-NMR (CDCl3): δ=1.37 (3H, t), 3.42 (1H, q), 3.86 (3H, s), 4.44 (2H, s), 5.92 (1H, s), 6.88 (3H, m).

References

[1] Patent: EP2813482, 2014, A1. Location in patent: Paragraph 0139; 0140

Vanillyl ethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Vanillyl ethyl ether Suppliers

Americas 2 China 103 Europe 1 Germany 2 India 2 Japan 1 United Kingdom 1 United States 16 USA 1 Global 129

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Penta Manufacturing Company

Tel: --
Fax: --
Email: sales@pentamfg.com
Country: United States
ProdList: 5076
Advantage: 65

Alfrebro LLC/ Archer Daniels Midland Company

Tel: --
Fax: --
Email: sforbis@alfrebro.com
Country: United States
ProdList: 768
Advantage: 58

Beijing Lys Chemicals Co, LTD.

Tel: --
Fax: --
Email: jiayanyong@lyschem.com
Country: United States
ProdList: 710
Advantage: 58

Excellentia International

Tel: --
Fax: --
Email: info@excellentiaint.com
Country: United States
ProdList: 567
Advantage: 58

Penta International Corporation

Tel: --
Fax: --
Email: lisaa@pentamfg.com
Country: United States
ProdList: 5042
Advantage: 58

WholeChem, LLC

Tel: --
Fax: --
Email: info@wholechem.com
Country: United States
ProdList: 814
Advantage: 58

Charkit Chemical Corporation

Tel: --
Fax: --
Email: sales@charkit.com
Country: United States
ProdList: 2993
Advantage: 65

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

More

Less

View Lastest Price from Vanillyl ethyl ether manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: Vanillyl ethyl ether 13184-86-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1
Release date: 2025-09-05

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Vanillyl ethyl ether 13184-86-6
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-20

JINING XINHE CHEMICAL CO., LTD

Product: Vanillyl ethyl ether 13184-86-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-07-19

13184-86-6, Vanillyl ethyl etherRelated Search:

Trinexapac-ethyl 2-Ethoxyethanol Vanillyl alcohol Ethylparaben Ethyl acetate ISOXADIFEN-ETHYL m-Cresol p-(2-Methoxyethyl) phenol Ethanol Guaiacol 2-Ethoxyphenol Ethylbenzene Dimethyl ether 3-Trifluoromethylphenol 4-Methoxyphenol Boron trifluoride diethyl etherate p-Cresol 4-Ethoxyphenol

VanilinEthylEther

4-HYDROXY-3-METHOXYBENZYL ETHYL ETHER

4-[ETHOXYMETHYL]-2-METHOXYPHENOL

Phenol, 4-(ethoxymethyl)-2-methoxy-

Vanilla alcohol ether

VANILLYL ETHYL ETHER

FEMA 3815

ETHYL VANILLYL ETHER

DAIRY ENHANCER

ETHYL 4-HYDROXY-3-METHOXYBENZYL ETHER

13184-86-6 Vanillyl ethyl ether

Xianglan alcohol ether

13184-86-6

13181-86-6

3184-86-6