3-BROMOISONICOTINIC ACID METHYL ESTER
- Product Name
- 3-BROMOISONICOTINIC ACID METHYL ESTER
- CAS No.
- 59786-31-1
- Chemical Name
- 3-BROMOISONICOTINIC ACID METHYL ESTER
- Synonyms
- Methyl-3-broMoisonicotiMate;Methyl 3-bromoisonicotinate;3-broMopyridine-4-carboxylate;Methyl 3-bromoisonicotinic acid;Methyl 3-bromoisonicotinate 98%;Methyl 3-bromopyridine-4-carboxylate;Methyl 3-bromo-4-pyridinecarboxylate;3-BROMOISONICOTINIC ACID METHYL ESTER;Methyl 3-bromo-isopyridin-3-carboxylate;3-broMopyridin-4-carboxylic acid Methyl ester
- CBNumber
- CB2194316
- Molecular Formula
- C7H6BrNO2
- Formula Weight
- 216.03
- MOL File
- 59786-31-1.mol
3-BROMOISONICOTINIC ACID METHYL ESTER Property
- Boiling point:
- 247℃
- Density
- 1.579
- refractive index
- 1.56
- Flash point:
- 103℃
- storage temp.
- Inert atmosphere,Room Temperature
- form
- clear liquid
- pka
- 0.76±0.18(Predicted)
- color
- Colorless to Yellow to Orange
- CAS DataBase Reference
- 59786-31-1
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M3103
- Product name
- Methyl 3-Bromoisonicotinate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- M3103
- Product name
- Methyl 3-Bromoisonicotinate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $119
- Updated
- 2025/07/31
- Product number
- M296460
- Product name
- Methyl 3-Bromoisonicotinate
- Packaging
- 10g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- X8341
- Product name
- Methyl 3-Bromoisonicotinate
- Packaging
- 25g
- Price
- $119
- Updated
- 2021/12/16
- Product number
- FB29015
- Product name
- 3-Bromoisonicotinic acid methyl ester
- Packaging
- 10g
- Price
- $160
- Updated
- 2021/12/16
3-BROMOISONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production
Uses
Methyl 3-bromoisonicotinate is an important chemical reagent, mainly used as organic synthesis or pharmaceutical intermediates for the preparation of compounds such as alkaloids, tricyclic compounds or small molecule enzyme inhibitors.
Synthesis
67-56-1
13959-02-9
59786-31-1
3.98 g (20 mmol, 1 eq.) of 3-bromoisonicotinic acid was dissolved in 50 ml of methanol and 4 ml of concentrated sulfuric acid was added as catalyst. The reaction mixture was heated to reflux. After completion of the reaction, it was cooled to room temperature and extracted three times with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. 2.65 g (62% yield) of methyl 3-bromoisonicotinate was obtained. The structure of the product was confirmed by 1H NMR (CDCl3): δ 4.02 (s, 3H), 7.64 (d, J = 4.9 Hz, 1H), 8.63 (d, J = 4.9 Hz, 1H), 8.88 (s, 1H).
References
[1] Patent: US2005/80085, 2005, A1. Location in patent: Page/Page column 12
[2] Patent: US2010/130477, 2010, A1. Location in patent: Page/Page column 58
[3] Patent: US2011/230495, 2011, A1. Location in patent: Page/Page column 23-24
[4] Advanced Synthesis and Catalysis, 2016, vol. 358, # 20, p. 3283 - 3292
3-BROMOISONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMOISONICOTINIC ACID METHYL ESTER manufacturers
- Product
- 3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-06
- Product
- 3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-14