ChemicalBook > CAS DataBase List > 3-BROMOISONICOTINIC ACID METHYL ESTER

3-BROMOISONICOTINIC ACID METHYL ESTER

Product Name
3-BROMOISONICOTINIC ACID METHYL ESTER
CAS No.
59786-31-1
Chemical Name
3-BROMOISONICOTINIC ACID METHYL ESTER
Synonyms
Methyl-3-broMoisonicotiMate;Methyl 3-bromoisonicotinate;3-broMopyridine-4-carboxylate;Methyl 3-bromoisonicotinic acid;Methyl 3-bromoisonicotinate 98%;Methyl 3-bromopyridine-4-carboxylate;Methyl 3-bromo-4-pyridinecarboxylate;3-BROMOISONICOTINIC ACID METHYL ESTER;Methyl 3-bromo-isopyridin-3-carboxylate;3-broMopyridin-4-carboxylic acid Methyl ester
CBNumber
CB2194316
Molecular Formula
C7H6BrNO2
Formula Weight
216.03
MOL File
59786-31-1.mol
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3-BROMOISONICOTINIC ACID METHYL ESTER Property

Boiling point:
247℃
Density 
1.579
refractive index 
1.56
Flash point:
103℃
storage temp. 
Inert atmosphere,Room Temperature
form 
clear liquid
pka
0.76±0.18(Predicted)
color 
Colorless to Yellow to Orange
CAS DataBase Reference
59786-31-1
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M3103
Product name
Methyl 3-Bromoisonicotinate
Purity
>98.0%(GC)
Packaging
1g
Price
$42
Updated
2025/07/31
TCI Chemical
Product number
M3103
Product name
Methyl 3-Bromoisonicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$119
Updated
2025/07/31
TRC
Product number
M296460
Product name
Methyl 3-Bromoisonicotinate
Packaging
10g
Price
$170
Updated
2021/12/16
AK Scientific
Product number
X8341
Product name
Methyl 3-Bromoisonicotinate
Packaging
25g
Price
$119
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB29015
Product name
3-Bromoisonicotinic acid methyl ester
Packaging
10g
Price
$160
Updated
2021/12/16
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3-BROMOISONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 3-bromoisonicotinate is an important chemical reagent, mainly used as organic synthesis or pharmaceutical intermediates for the preparation of compounds such as alkaloids, tricyclic compounds or small molecule enzyme inhibitors.

Synthesis

67-56-1

13959-02-9

59786-31-1

3.98 g (20 mmol, 1 eq.) of 3-bromoisonicotinic acid was dissolved in 50 ml of methanol and 4 ml of concentrated sulfuric acid was added as catalyst. The reaction mixture was heated to reflux. After completion of the reaction, it was cooled to room temperature and extracted three times with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. 2.65 g (62% yield) of methyl 3-bromoisonicotinate was obtained. The structure of the product was confirmed by 1H NMR (CDCl3): δ 4.02 (s, 3H), 7.64 (d, J = 4.9 Hz, 1H), 8.63 (d, J = 4.9 Hz, 1H), 8.88 (s, 1H).

References

[1] Patent: US2005/80085, 2005, A1. Location in patent: Page/Page column 12
[2] Patent: US2010/130477, 2010, A1. Location in patent: Page/Page column 58
[3] Patent: US2011/230495, 2011, A1. Location in patent: Page/Page column 23-24
[4] Advanced Synthesis and Catalysis, 2016, vol. 358, # 20, p. 3283 - 3292

3-BROMOISONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMOISONICOTINIC ACID METHYL ESTER Suppliers

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View Lastest Price from 3-BROMOISONICOTINIC ACID METHYL ESTER manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-06
Dideu Industries Group Limited
Product
3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-27
Career Henan Chemical Co
Product
3-BROMOISONICOTINIC ACID METHYL ESTER 59786-31-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-14

59786-31-1, 3-BROMOISONICOTINIC ACID METHYL ESTERRelated Search:

Bromisoval 2-Bromopropane Methyl 3-bromopropionate Methyl 3-bromobenzoate 1-Bromo-2-methylpropane Chlorobromoisocyanurate 3-Bromoisonicotinic acid METHYL 2-AMINO-5-BROMO-4-PYRIDINECARBOXYLATE 5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER 3-BROMOISONICOTINIC ACID METHYL ESTER 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE Methyl 5-bromo-2-chloroisonicotinate 3-BROMO-4-(METHOXYCARBONYL)-1-METHYLPYRIDINIUM SPECS AO-801/41077573 SPECS AO-801/41077570

  • 3-BROMOISONICOTINIC ACID METHYL ESTER
  • 3-BROMOPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
  • Methyl 3-bromopyridine-4-carboxylate
  • 3-broMopyridin-4-carboxylic acid Methyl ester
  • Methyl-3-broMoisonicotiMate
  • 3-broMopyridine-4-carboxylate
  • Methyl 3-bromo-4-pyridinecarboxylate
  • Methyl 3-bromoisonicotinate
  • Methyl 3-bromoisonicotinate 98%
  • Methyl 3-bromoisonicotinic acid
  • 4-Pyridinecarboxylic acid, 3-bromo-, methyl ester
  • 3-BROMOISONICOTINIC ACID METHYL ESTER ISO 9001：2015 REACH
  • 4-Pyridinecarboxylic acid, 3-bromo-, methyl ester (9CI, ACI)
  • 3-bromo-4-Pyridinecarboxylic acid methyl ester (9CI ACI)
  • Methyl 3-bromo-isopyridin-3-carboxylate
  • 59786-31-1
  • blocks
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  • Pyridine