5,5′-Dithiobis(2-nitrobenzoic acid)

ChemicalBook > CAS DataBase List > 5,5′-Dithiobis(2-nitrobenzoic acid)

5,5′-Dithiobis(2-nitrobenzoic acid)

Product Name: 5,5′-Dithiobis(2-nitrobenzoic acid)
CAS No.: 69-78-3
Chemical Name: 5,5′-Dithiobis(2-nitrobenzoic acid)
Synonyms: DTNB;Ba-2767;5,5'Ellmanns;5,5&priMe;Ellmsn'sreagent;ELLMANS' REAGENT;ELLMAN'S REAGENT;ellmann's reagent;SAPONIN BIOCHEMICAL
CBNumber: CB2215444
Molecular Formula: C14H8N2O8S2
Formula Weight: 396.35
MOL File: 69-78-3.mol

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5,5′-Dithiobis(2-nitrobenzoic acid) Property

Melting point:: 240-245 °C (dec.)(lit.)
Boiling point:: 671.9±55.0 °C(Predicted)
Density: 1.67
refractive index: 1.6900 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Yellow solid
pka: 1.57±0.25(Predicted)
color: Pale Yellow to Light Yellow
Water Solubility: Soluble in water and ethanol.
Merck: 14,3551
BRN: 1896821
Stability:: Stable. Incompatible with strong bases, strong oxidizing agents.
InChIKey: KIUMMUBSPKGMOY-UHFFFAOYSA-N
CAS DataBase Reference: 69-78-3(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 3,3'-dithiobis[6-nitro- (69-78-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: DG9650000
F: 10
TSCA: Yes
HS Code: 29309070

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D218200
Product name: 5,5′-Dithiobis(2-nitrobenzoic acid)
Purity: ReagentPlus , 99%
Packaging: 1g
Price: $32.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 322123
Product name: 5,5ʹ-Dithio-bis-(2-nitrobenzoic Acid) - CAS 69-78-3 - Calbiochem
Purity: Sulfhydryl reagent used to characterize reactive SH groups.
Packaging: 5G
Price: $140
Updated: 2024/03/01

TCI Chemical

Product number: D0944
Product name: 5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: D0944
Product name: 5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $75
Updated: 2024/03/01

Alfa Aesar

Product number: A14331
Product name: 5,5'-Dithiobis(2-nitrobenzoic acid), 99%
Packaging: 1g
Price: $34.9
Updated: 2024/03/01

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5,5′-Dithiobis(2-nitrobenzoic acid) Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Uses

Reagent for determination of sufhydryl groups.5,5'-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.

Uses

5,5′-Dithiobis(2-nitrobenzoic acid) is a water soluble reagent mainly used for the derivatization of sulfhydryl groups.

Uses

5,5′-Dithiobis(2-nitrobenzoic acid) is an membrane-impermeant thiol/disulfide exchange blocker. It is also used to quantify the number or concentration of thiol groups in a sample.

Definition

ChEBI: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.

General Description

5,5′-Dithiobis(2-nitrobenzoic acid) is also called DTNB or Ellman′s reagent. It is a water soluble reagent, which interacts with thiol groups, and can be used conveniently at neutral pH. Thiolate anion (RS^-) reacts with Ellman′s reagent (DTNB^2-), to produce 2-nitro-5-thiobenzoate anion (TNB^2-) and one mixed disulfide (R-S-TNB^-). TNB^2- has a high molar absorption coefficient, and absorbs at 412nm. This absorption is independent of pH, at pH> 7.3.

5,5′-Dithiobis(2-nitrobenzoic acid) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5,5′-Dithiobis(2-nitrobenzoic acid) manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5,5′-Dithiobis(2-nitrobenzoic acid) 69-78-3
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-24

Hebei Yanxi Chemical Co., Ltd.

Product: 5,5′-Dithiobis(2-nitrobenzoic acid) 69-78-3
Price: US $100.00-10.00/kgkg
Min. Order: 1kgkg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-09-28

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5,5′-Dithiobis(2-nitrobenzoic acid)/DTNB 69-78-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 100KG
Release date: 2021-06-01

69-78-3, 5,5′-Dithiobis(2-nitrobenzoic acid)Related Search:

Thiamine disulfide LITHIUM PERIODATE Folic acid Ethyl 2-(Chlorosulfonyl)acetate 4-Nitrobenzoic acid 2-Nitrobenzoic acid 4-Nitrophenyl chloroformate Ascoric Acid 3,3'-DICARBOXYLIC ACID DIPHENYL DISULFIDE 4,4'-Dithiodianiline METHYL PHENYL DISULFIDE 4,4'-Dinitrodiphenyl disulfide 2-Nitrobenzaldehyde DIPHENYL DISULFIDE 4-NITROTHIOPHENOL 2-NITROSOTOLUENE 2-Nitrobenzyl alcohol Thiobenzoic acid

DTNB

ellmann's reagent

ELLMAN'S REAGENT

ELLMANS' REAGENT

BIS(3-CARBOXY-4-NITROPHENYL) DISULFIDE

3-CARBOXY-4-NITROPHENYL DISULFIDE

Ellmsn'sreagent

Bis(3-carboxy-4-nitrophenyl) disulphide~3-Carboxy-4-nitrophenyl disulphide~Ellmans

Ellmanns

5,5'-Dithobis(2-Nitrobenzoic Acid)

5,5'-DITHIO-BIS(2-NITROBENZOIC ACID) (3, 3'-6)

5.5'-Dithio-Bis-(2-NitrobenzoicAcid)A.R.

Dithiobis(2-nitrobenzoic acid)

5,5-Dithiobis(2-nitrobenzoic acid)product (DTNB)

Benzoic acid, 3,3-dithiobis6-nitro-

5-[(3-CARBOXY-4-NITROPHENYL)DITHIO]-2-NITROBENZOICACID(5,5-DITHIOBIS(2-NITROBENZOICACID))

5,5-Dithiobis(2-nitrobenzoic acid) (DTNB)

5,5'-DITHIOBIS(2-NITROBENZOIC ACID)

5,5-DITHIO-BIS(2-NITROBENZOIC ACID)

5-[(3-CARBOXY-4-NITROPHENYL)DITHIO]-2-NITROBENZOIC ACID

6,6'-DINITRO-3,3'-DITHIODIBENZOIC ACID

2,2'-DINITRO-5,5'-DITHIODIBENZOIC ACID

dithionitrobenzoicacid

(3-Carboxy-4-nitrophenyl)disulphide, DTNB, Ellman's reagent

5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]

5,5-DITHIOBIS(2-NITROBENZOIC ACID) extrapure

5,5'-Dithiobis(2-nitrobenzoic acid) Vetec(TM) reagent grade, 98%

SAPONIN BIOCHEMICAL

DTNB, 5,5'-Dithiobis-(2-nitrobenzoic acid)

DTNB Ellman's Reagent

2,2’-dinitro-5,5’-dithiodibenzoesaeure

3,3’-dithiobis(6-nitro-benzoicaci

3,3’-dithiobis(6-nitrobenzoicacid)

3,3’-dithiobis[6-nitro-benzoicaci

5,5’-dithiobis(2-nitrobenzoic

3-Carboxy-4-nitrophenyl disulfide, 6,6μ-Dinitro-3,3μ-dithiodibenzoic acid, Bis(3-carboxy-4-nitrophenyl) disulfide, DTNB, Ellmans Reagent

5,5'-Dithiobis(2-nitrobenzoic acid) ,98%

5,5'-DITHIOBIS(2-NITROBENZOICACID) RESEARCH GRADE

5,5′-Dithiobis(2-nitrobenzoic acid),3-Carboxy-4-nitrophenyl disulfide, 6,6′-Dinitro-3,3′-dithiodibenzoic acid, Bis(3-carboxy-4-nitrophenyl) disulfide, DTNB, Ellman’s Reagent

3-Carboxy-4-nitrophe

5-(3-Carboxy-4-nitrophenyl)disulfanyl-2-nitrobenzoic acid

5,5'-Dithiobis(2-nitrobenzoic acid) ,99%

Ba-2767

Di(3-carboxy-4-nitrophenyl) persulfide

Di(3-carboxy-4-nitrophenyl)persulfide

Bis(3-carboxy-4-nitrophenyl) Disulphide

Bis(3-carboxy-4-nitrophenyl) Disulfide DTNB Ellman's Reagent

5-Dithiobis(2-nitrobenzoic acid)

5,5'-disulfanediylbis(2-nitrobenzoic acid)

5,5&priMe

5,5 'twothiobis(2-Nitrobenzoic Acid

5,5'-Dithiobis(2-nitrobenzoic acid) ReagentPlus(R), 99%

Dithiobis(2-nitrobenzoic acid) research grade

5,5-Dithio-bis-(2-nitrobenzoic Acid) - CAS 69-78-3 - Calbiochem

5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]&gt

ithionitrobenzoicaci

5,5′-Dithiobis(2-nitrobenzoic acid) ISO 9001：2015 REACH

3-Carboxy-4-nitrophenyl disulfide 69-78-3