ChemicalBook > CAS DataBase List > GANGLIOSIDE GD1A DISODIUM SALT

GANGLIOSIDE GD1A DISODIUM SALT

Product Name
GANGLIOSIDE GD1A DISODIUM SALT
CAS No.
12707-58-3
Chemical Name
GANGLIOSIDE GD1A DISODIUM SALT
Synonyms
GD1A;GD1A 2NA;Ganglioside B1;Ganglioside GII;GANGLIOSIDE GD1A;GD1A-GANGLIOSIDE;disialogangloside GD1a;DISIALOGANGLIOSIDE GD1A;DISIALOGANGLIOSIDE GDIA;GD1a-Ganglioside sodium
CBNumber
CB2218829
Molecular Formula
C84H146N4Na2O39
Formula Weight
1882.04098
MOL File
12707-58-3.mol
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GANGLIOSIDE GD1A DISODIUM SALT Property

storage temp. 
-20°C
solubility 
DMSO: soluble
form 
lyophilized powder
BRN 
6228822
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
29400090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G2392
Product name
Disialoganglioside GD1a from bovine brain
Purity
≥95% (TLC), lyophilized powder
Packaging
1mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
G2392
Product name
Disialoganglioside GD1a from bovine brain
Purity
≥95% (TLC), lyophilized powder
Packaging
5mg
Price
$669
Updated
2024/03/01
Cayman Chemical
Product number
15585
Product name
Ganglioside GD1a (sodium salt)
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
15585
Product name
Ganglioside GD1a (sodium salt)
Purity
≥98%
Packaging
5mg
Price
$262
Updated
2024/03/01
TRC
Product number
G235070
Product name
GangliosideGD1aDisodiumSalt
Packaging
1mg
Price
$195
Updated
2021/12/16
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GANGLIOSIDE GD1A DISODIUM SALT Chemical Properties,Usage,Production

Description

Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.

Chemical Properties

White powder

Uses

Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.

General Description

Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.

GANGLIOSIDE GD1A DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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12707-58-3, GANGLIOSIDE GD1A DISODIUM SALTRelated Search:


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  • 12707-58-3
  • C84H148N4O39
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  • Biochemicals and Reagents
  • Acidic glycosphingolipids
  • BioChemical
  • Sphingolipids
  • Lipids
  • Gangliosides